Abstract: A modular super-calculation architecture comprises a plurality of electronic calculation modules communicating with each other in a network and liquid cooled. Each electronic calculation module includes a calculation node, one or more autonomous liquid cooling devices, an electric power device, a box-like container that encloses and protects inside it at least the calculation node, the electric power device, and the one or more liquid cooling devices. Each electronic calculation module is independent hydraulically, electrically, in terms of network communication and mechanically at least from the other electronic calculation modules, and can be inserted and/or removed or substituted hot from said architecture.