Abstract: Methods of determining a risk of mortality are disclosed. In one arrangement, the method comprises receiving patient data representing information about a cancer patient. A mathematical model of mortality risk is used to determine the risk of mortality of the cancer patient based on the received patient data. The mathematical model models a relationship determined from training data between the risk of mortality and values of at least 16 model parameters.

Abstract: The present invention relates to a liquisolid pharmaceutical formulation comprising a porous carrier and an active pharmaceutical ingredient loaded onto a surface of the porous carrier, wherein the active pharmaceutical ingredient is dispersed in propylene carbonate or a mixture of propylene carbonate and a further solvent and the dispersion of the active pharmaceutical ingredient and propylene carbonate or a mixture of propylene carbonate and a further solvent is loaded onto the external surface and the internal surface located inside the pores of the porous carrier thereby forming a liquisolid system, and to a process for manufacturing such a liquisolid pharmaceutical formulation.

Abstract: The application relates to methods of assessing whether a cancer patient is at high risk or low risk of mortality, as well as methods of predicting the treatment response to an anti-cancer therapy in a cancer patient. The methods of the invention find application in the selection of patients for clinical trials, the selection of patients for treatment with anti-cancer therapies, monitoring cancer patients during treatment with an anti-cancer therapy, and evaluating the results of clinical trials for anti-cancer therapies, for example.

Abstract: The invention relates to a receptacle (4) for receiving a sample (5) during an optical analysis of the sample (5), wherein the receptacle (4) comprises a bottom (19) which is at least partially transparent so that the sample (5) within the receptacle (4) can be optically analyzed by an image sensor (6) from below the bottom (19) and wherein the bottom (19) is very thin thereby improving contrast and sharpness of the images generated by the image sensor (6). Further, the invention relates to a system for optically analyzing a sample (5).

Abstract: A computer-implemented knowledge acquisition system which enables user to easily create and share electronic study material is disclosed. The system includes a content creation module which can be configured to receive question data and answer data input by a first user and create a package content file using the input data. The content creation module includes a multimedia library from which images, video, and audio can be selected for inclusion in the package content file. The system also has a package distribution module which allows users to send the package content files to one or more users using a variety of transferring techniques.

Abstract: A computer-implemented knowledge acquisition system which enables user to easily create and share electronic study material is disclosed. The system includes a content creation module which can be configured to receive question data and answer data input by a first user and create a package content file using the input data. The content creation module includes a multimedia library from which images, video, and audio can be selected for inclusion in the package content file. The system also has a package distribution module which allows users to send the package content files to one or more users using a variety of transferring techniques.