Abstract: Methods of delivering and using an annuloplasty ring to reshape a valve annulus are disclosed. The methods include obtaining an annuloplasty ring having an elastic inner core member. The elastic inner core member can be defined by a multi-stranded braided cable. The inner core member has an unstressed closed or open ring shape and a first elastic modulus that enables the core member to be compressed from the unstressed ring shape into a stressed narrow shape and enables the annuloplasty ring to reshape a native heart valve annulus. The methods can include converting the annuloplasty ring from the unstressed ring shape into the stressed narrow shape, passing the annuloplasty ring through an access tube positioned with a distal tip adjacent a native valve annulus, and expelling the annuloplasty ring from the distal tip of the access tube so that it self-converts back towards the unstressed ring shape.

Abstract: Methods of delivering and using an annuloplasty ring to reshape a valve annulus are disclosed. The methods include obtaining an annuloplasty ring having an elastic inner core member. The elastic inner core member can be defined by a multi-stranded braided cable. The inner core member has an unstressed closed or open ring shape and a first elastic modulus that enables the core member to be compressed from the unstressed ring shape into a stressed narrow shape and enables the annuloplasty ring to reshape a native heart valve annulus. The methods can include converting the annuloplasty ring from the unstressed ring shape into the stressed narrow shape, passing the annuloplasty ring through an access tube positioned with a distal tip adjacent a native valve annulus, and expelling the annuloplasty ring from the distal tip of the access tube so that it self-converts back towards the unstressed ring shape.

Abstract: An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. In addition, selective placement of point-welds or other such control points locally control other parameters such as the amount and direction of displacement as the ring undergoes external loading. Cable with well-placed control points result in a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as for example 1 cm×1 cm, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle and allowing for asymmetrical deflection to be designed into the product.

Abstract: Methods of delivering and using an annuloplasty ring to reshape a valve annulus are disclosed. The methods include obtaining an annuloplasty ring having an elastic inner core member. The elastic inner core member can be defined by a multi-stranded braided cable. The inner core member has an unstressed closed or open ring shape and a first elastic modulus that enables the core member to be compressed from the unstressed ring shape into a stressed narrow shape and enables the annuloplasty ring to reshape a native heart valve annulus. The methods can include converting the annuloplasty ring from the unstressed ring shape into the stressed narrow shape, passing the annuloplasty ring through an access tube positioned with a distal tip adjacent a native valve annulus, and expelling the annuloplasty ring from the distal tip of the access tube so that it self-converts back towards the unstressed ring shape.

Abstract: An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the triscuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. In addition, selective placement of point-welds or other such control points locally control other parameters such as the amount and direction of displacement as the ring undergoes external loading. Cable with well-placed control points result in a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as for example 1 cm×1 cm, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle and allowing for asymmetrical deflection to be designed into the product.

Abstract: An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the triscuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. In addition, selective placement of point-welds or other such control points locally control other parameters such as the amount and direction of displacement as the ring undergoes external loading. Cable with well-placed control points result in a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as for example 1 cm×1 cm, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle and allowing for asymmetrical deflection to be designed into the product.

Abstract: An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. In addition, selective placement of point-welds or other such control points locally control other parameters such as the amount and direction of displacement as the ring undergoes external loading. Cable with well-placed control points result in a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as for example 1 cm×1 cm, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle and allowing for asymmetrical deflection to be designed into the product.

Abstract: A bionanochip cartridge for analysis of multiple samples or analytes is provided herein, and the cartridge is dimensioned to take advantage of existing robotic microtiter plate handling equipment. Fluidics are specially designed to provide a small footprint and to prevent cross contamination.

Abstract: A bionanochip cartridge for analysis of multiple samples or analytes is provided herein, and the cartridge is dimensioned to take advantage of existing robotic microtiter plate handling equipment. Fluidics are specially designed to provide a small footprint and to prevent cross contamination.

Abstract: Neural net method of computing oral cancer risk based on inputs such as age, gender, smoking status, morphological characteristics of sampled cells, and levels of biomarkers in samples cells.

Abstract: An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. In addition, selective placement of point-welds or other such control points locally control other parameters such as the amount and direction of displacement as the ring undergoes external loading. Cable with well-placed control points result in a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as for example 1 cm×1 cm, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle and allowing for asymmetrical deflection to be designed into the product.