Patents by Inventor Tim Bartels

Tim Bartels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130309690
    Abstract: The present invention provides the surprising finding that alpha-synuclein exists in vivo as a folded tetramer. Provided are various methods and technologies that arise from this finding, including methods and kits for identifying individuals susceptible to or suffering from certain diseases, disorders or conditions associated with stability of alpha-synuclein tetramers, and/or individuals likely (or not) to respond to therapy with agents that alter level and/or stability of alpha-synuclein tetramers.
    Type: Application
    Filed: November 4, 2011
    Publication date: November 21, 2013
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., BRANDEIS UNIVERSITY
    Inventors: Dagmar Ringe, Gregory A. Petsko, Dennis J. Selkoe, Tim Bartels
  • Publication number: 20130289022
    Abstract: Disclosed herein are methods and related compositions for identifying compounds that stabilize natively folded tetrameric ?-synuclein. These methods and compositions are useful for the treatment and diagnosis of ?-synuclein-associated diseases and disorders.
    Type: Application
    Filed: November 4, 2011
    Publication date: October 31, 2013
    Applicant: BRANDEIS UNIVERSITY
    Inventors: Dagmar Ringe, Gregory A. Petsko, Dennis J. Selkoe, Tim Bartels