Abstract: Systems and methods for the automated demineralization of bone and decellularization of soft tissue include a mixing assembly communicatively coupled with a control and reporting system. The mixing assembly includes a housing that supports a cannister sub-assembly forming a mixing chamber having a reagent inlet, a reagent outlet, and an internal fluid agitator. A motor is operably coupled with the agitator and configured to spin the agitator in first and second directions relative to the cannister, thereby agitating fluid contained within the mixing chamber. At least one pump is configured to progressively inject measured quantities of a plurality of reagents into the mixing chamber. The associated control and reporting system includes a user terminal that displays a graphical user interface enabling a user to initiate an automated demineralization or decellularization procedure in which the mixing assembly demineralizes tissue placed within the mixing chamber. Other embodiments are also disclosed.

Abstract: Methods and apparatuses, including computer program products, are described for assigning a risk profile to a guarantee product and charging associated fees. Risk profiles are established, each based on a risk level. A first risk profile is assigned to the guarantee product based on an initial allocation of assets in a linked investment account. A periodic determination is made as to whether the guarantee product is in compliance with the first risk profile due to initial asset allocation changes, including determining whether the asset allocation satisfies the risk level of the first risk profile. A second risk profile is assigned whenever the guarantee product is no longer in compliance with the first risk profile based on the current allocation of assets.

Abstract: Methods and apparatuses, including computer program products, are described for charging of fees associated with a guarantee product. A computing device calculates a fee associated with the guarantee product, wherein the guarantee product is linked to a first investment account. The computing device deducts the calculated fee from a second account if deduction of the fee from the second account can be completed. The computing device deducts the calculated fee from the first investment account if deduction from the second account cannot be completed, and a guarantee associated with the guarantee product is adjusted based on deduction of the calculated fee from the first investment account.