Patents by Inventor Tim Bolle

Tim Bolle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10765521
    Abstract: An artificial cartilage is provided whereby a fixed negative charged hydrogel has been infused within a restrictive swelling network, which limits and restricts the thickness of the artificial cartilage. At least 60% of the volume of the artificial cartilage is composed of the restricted and swollen hydrogel. The restrictive swelling network restricts the hydrogel to swell not more than 10% with respect to its maximum swelling capacity, i.e. a swelling capacity to swell 10-fold more is retained. The hydrogel within the restrictive swelling network has an equilibrium stiffness between 0.5 and 2 MPa to resist external loads applied to the top surface layer or the bottom surface layer of the artificial cartilage. The hydrogel has a fixed negative charge density of ?0.17 to ?0.23 mEg/ml and is capable of swelling between 2-15 times compared to the volume of the hydrogel without being restricted.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: September 8, 2020
    Assignees: Technische Universiteit Eindhoven, RWTH Aachen
    Inventors: Corrinus Cornelis van Donkelaar, Keita Ito, Tim Bolle
  • Publication number: 20190231534
    Abstract: An artificial cartilage is provided whereby a fixed negative charged hydrogel has been infused within a restrictive swelling network, which limits and restricts the thickness of the artificial cartilage. At least 60% of the volume of the artificial cartilage is composed of the restricted and swollen hydrogel. The restrictive swelling network restricts the hydrogel to swell not more than 10% with respect to its maximum swelling capacity, i.e. a swelling capacity to swell 10-fold more is retained. The hydrogel within the restrictive swelling network has an equilibrium stiffness between 0.5 and 2 MPa to resist external loads applied to the top surface layer or the bottom surface layer of the artificial cartilage. The hydrogel has a fixed negative charge density of ?0.17 to ?0.23 mEg/ml and is capable of swelling between 2-15 times compared to the volume of the hydrogel without being restricted.
    Type: Application
    Filed: October 19, 2017
    Publication date: August 1, 2019
    Inventors: Corrinus Cornelis van Donkelaar, Keita Ito, Tim Bolle