Abstract: A liquid resistant barrier for structural openings such as doors, windows, vents, or the like for use during floods or storms is disclosed. A barrier frame is placed within and about the periphery of the opening, with a gasket located on the structural side, to form a seal. A barrier frame cover, with a corresponding barrier frame cover gasket, is placed over the barrier frame and compression fittings used to hold them together. The gaskets form a seal that is impermeable to liquids and the barrier frame cover prevents damage by flotsam or dynamic pressure.