Patents by Inventor Tim Gaekens

Tim Gaekens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nalmefene prodrugs
    Patent number: 8440686
    Abstract: The present invention relates to ester prodrugs of nalmefene of formula (I), pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment of substance abuse disorders such as alcohol abuse and alcohol dependence and impulse control disorders such as pathological gambling and addiction to shopping.
    Type: Grant
    Filed: April 23, 2009
    Date of Patent: May 14, 2013
    Assignee: Janssen Pharmaceutica NV
    Inventors: Michel Joseph Maurice André Guillaume, Tim Gaekens
  • PRO-DRUGS OF (E)-7-(3-(2-AMINO-1-FLUOROETHYLIDENE)PIPERIDIN-1-YL)-1-CYCLOPROPYL-6-FLUORO-8-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
    Publication number: 20110172193
    Abstract: The present invention is directed to pro-drugs of (E)-7-(3-(2-amino-1-fluoroethylidene)piperidin-1-yl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, pharmaceutical compositions containing them and the use of said pro-drugs and pharmaceutical compositions as antimicrobial agents against pathogenic microorganisms, particularly against resistant microbes.
    Type: Application
    Filed: January 3, 2011
    Publication date: July 14, 2011
    Inventors: Mark MACIELAG, Gary Eichenbaum, Tim Gaekens, Michel Guillaume, Brian Shook
  • NALMEFENE DI-ESTER PRODRUGS
    Publication number: 20110053971
    Abstract: The present invention relates to prodrugs of nalmefene of formula (I), pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment of substance abuse disorders such as alcohol abuse and alcohol dependence and impulse control disorders such as pathological gambling and addiction to shopping.
    Type: Application
    Filed: April 23, 2009
    Publication date: March 3, 2011
    Applicant: JANSSEN PHARMACEUTICA NV
    Inventors: Michel Joseph Maurice André Guillaume, Tim Gaekens
  • NALMEFENE PRODRUGS
    Publication number: 20110034502
    Abstract: The present invention relates to ester prodrugs of nalmefene of formula (I), pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment of substance abuse disorders such as alcohol abuse and alcohol dependence and impulse control disorders such as pathological gambling and addiction to shopping.
    Type: Application
    Filed: April 23, 2009
    Publication date: February 10, 2011
    Inventors: Michel Joseph, Maurice, Andre Guillaume, Tim Gaekens