Patents by Inventor Tim Heiseler

Tim Heiseler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • General strategy for antibody library screening
    Patent number: 9733240
    Abstract: A generally applicable method for the selective covalent attachment of a reporter molecule to a replicating entity that allows one to obtain specific binders from a single round of library screening is disclosed. For example, selective biotinylation of phage particles and yeast cells displaying a binder to any given target can be achieved via application of a coupled enzyme reaction that includes a peroxidase, an oxidase and a catalase.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: August 15, 2017
    Assignee: Merck Patents GmbH
    Inventors: Stefan Becker, Tim Heiseler, Alexander Maass, Harald Kolmar
  • GENERAL STRATEGY FOR ANTIBODY LIBRARY SCREENING
    Publication number: 20140357514
    Abstract: A generally applicable method for the selective covalent attachment of a reporter molecule to a replicating entity that allows one to obtain specific binders from a single round of library screening is disclosed. For example, selective biotinylation of phage particles and yeast cells displaying a binder to any given target can be achieved via application of a coupled enzyme reaction that includes a peroxidase, an oxidase and a catalase.
    Type: Application
    Filed: December 14, 2012
    Publication date: December 4, 2014
    Inventors: Stefan Becker, Tim Heiseler, Alexander Maass, Harald Kolmar