Abstract: The disclosed technology is generally directed to graph queries with reduced latencies. In one example of the technology, there is a cross-tenancy collaboration between two different tenancies: a first tenancy that is homed in a first geographical region and a second tenancy that is homed in a second geographical region. In the first geographical region, a first set of graph data is stored. The first set of the graph data is associated with the first tenancy. A portion of the first set of the graph data to be copied from the first geographical region to the second geographical region is determined. In response to determining the portion of the first set of the graph data, a copy of the portion of the first set of the graph data is stored in the second geographical region.

Abstract: The present invention is directed to devices and methods that efficiently and safely kill pathogens in blood functions by the generation of metal ions in situ. Such metal ions include silver ions, copper ions, and gold ions; however, additional metals can be employed for generation of ions in situ, including platinum, iridium, and zinc. The activity of the devices and methods of the present invention is extremely broad, and can kill pathogenic bacteria, viruses, and fungi. The activity of the devices and methods of the present invention does not depend on specific interactions between the device and the surface of the pathogen being killed. Additionally, the activity of the devices and methods is not subject to the development of resistance by the pathogen, such as can occur subsequent to the administration of conventional antibacterial, antifungal, or antiviral agents.

Abstract: A device for killing blood-borne pathogens, and a method of using the device to effectively remove the blood-borne pathogens from a body of a human or an animal is claimed. The device comprises a wire that is inserted into a bloodstream of a patient, which releases metallic ions which effectively kill the pathogens. There are several embodiments, each of which has a combination of covered and uncovered portions of the wire. The wire is electrically connected to both a source of power and a power supply with printed circuit board or controller/software, which controls the intensity and duration of the treatment.

Abstract: A device for killing blood-borne pathogens, and a method of using the device to effectively remove the blood-borne pathogens from a body of a human or an animal is claimed. The device comprises a wire that is inserted into a bloodstream of a patient, which releases metallic ions which effectively kill the pathogens. There are several embodiments, each of which has a combination of covered and uncovered portions of the wire. The wire is electrically connected to both a source of power and a power supply with a printed circuit board or a controller/software, which controls an intensity and a duration of a treatment.

Abstract: A device for killing blood-borne pathogens, and a method of using this device to effectively remove blood-borne pathogens from the body of a human or animal is claimed. The device comprises a wire that is inserted into the blood stream of a patient, which releases metallic ions which effectively kill the pathogens. There are several embodiments, each of which has a combination of covered and uncovered portions of the wire. The wire is electrically connected to both a source of power and a Power Supply with PCB or controller/software, which controls the intensity and during of the treatment.

Abstract: The present invention relates to formulations comprising A) sphinganine and B) at least one active ingredient selected from the group creatine, creatinine, caffeine, carnitine, biotin, arjunolic acid, xymenynic acid, minoxidil, arginine and derivatives thereof.

Abstract: The invention relates to a process for the production of 4-aminobutyric acid, also referred to as gamma-aminobutyric acid, in short GABA, to a process for the production of an extract comprising 4-aminobutyric acid, to a process for the preparation of a cosmetic formulation comprising 4-aminobutyric acid, and to the use of Cyanidium caldarium cells or cell components in cosmetic applications.

Abstract: The invention relates to the use of sphinganine for improving the visual appearance of skin and hair, for caring for, for protecting and/or for stimulating the growth of skin and hair.

Abstract: The invention relates to genetically modified Pichia ciferrii cells, to the use thereof and to a method of producing sphingoid bases and sphingolipids.

Abstract: The invention relates to genetically modified Pichia ciferrii cells, to the use thereof and to a method of producing sphingoid bases and sphingolipids.

Abstract: The invention relates to genetically modified Pichia ciferrii cells, to the use thereof and to a method of producing sphingoid bases and sphingolipids.

Abstract: The invention relates to novel enzymes that provide acetylated sphingoid bases.

Abstract: The present invention relates to formulations comprising A) sphinganine and B) at least one active ingredient selected from the group creatine, creatinine, caffeine, carnitine, biotin, arjunolic acid, xymenynic acid, minoxidil, arginine and derivatives thereof.

Abstract: The invention relates to novel enzymes that provide acetylated sphingoid bases.

Abstract: The invention relates to the use of a protein homologous to a MeaB protein for increasing the enzymatic activity of a 3-hydroxycarboxylic acid-CoA mutase, a fusion protein comprising a 3-hydroxycarboxylic acid-CoA mutase and a protein sequence homologous to a MeaB protein and an enzymatic method for producing 2-hydroxyisobutryric acid.

Abstract: The invention relates to a cosmetic formulation and to its use.

Abstract: The invention relates to a process for the production of 4-aminobutyric acid, also referred to as gamma-aminobutyric acid, in short GABA, to a process for the production of an extract comprising 4-aminobutyricacid, to a process for the preparation of a cosmetic formulation comprising 4-aminobutyricacid, and to the use of Cyanidium caldarium cells or cell components in cosmetic applications.

Abstract: The invention relates to genetically modified Pichia ciferrii cells, to the use thereof and to a method of producing sphingoid bases and sphingolipids.

Abstract: The invention relates to the use of sphinganine for improving the visual appearance of skin and hair, for caring for, for protecting and/or for stimulating the growth of skin and hair.

Abstract: The invention relates to the use of 13-hydroxy-9,11-octadecadienoic acid for tanning human skin and methods associated therewith.