Patents by Inventor Tim Leiner

Tim Leiner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12089977
    Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analyzing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.
    Type: Grant
    Filed: May 11, 2021
    Date of Patent: September 17, 2024
    Assignee: Pie Medical Imaging B.V.
    Inventors: Ivana Isgum, Majd Zreik, Tim Leiner, Jean-Paul Aben
  • Publication number: 20210334963
    Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analyzing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.
    Type: Application
    Filed: May 11, 2021
    Publication date: October 28, 2021
    Applicant: Pie Medical Imaging B.V.
    Inventors: Ivana Isgum, Majd Zreik, Tim Leiner, Jean-Paul Aben
  • Patent number: 11004198
    Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analysing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: May 11, 2021
    Assignee: Pie Medical Imaging B.V.
    Inventors: Ivana Isgum, Majd Zreik, Tim Leiner
  • Publication number: 20190333216
    Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analysing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.
    Type: Application
    Filed: July 11, 2019
    Publication date: October 31, 2019
    Applicant: Pie Medical Imaging B.V.
    Inventors: Ivana Isgum, Majd Zreik, Tim Leiner
  • Patent number: 10395366
    Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analyzing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: August 27, 2019
    Assignee: Pie Medical Imaging B.V.
    Inventors: Ivana Isgum, Majd Zreik, Tim Leiner
  • Publication number: 20190139219
    Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analysing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.
    Type: Application
    Filed: January 7, 2019
    Publication date: May 9, 2019
    Applicant: Pie Medical Imaging B.V.
    Inventors: Ivana Isgum, Majd Zreik, Tim Leiner
  • Patent number: 10176575
    Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analyzing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: January 8, 2019
    Assignee: Pie Medical Imaging B.V.
    Inventors: Ivana Isgum, Majd Zreik, Tim Leiner
  • Publication number: 20180276817
    Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analysing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.
    Type: Application
    Filed: March 23, 2018
    Publication date: September 27, 2018
    Applicant: UMC Utrecht Holding B.V.
    Inventors: Ivana Isgum, Majd Zreik, Tim Leiner
  • Patent number: 6479996
    Abstract: A magnetic resonance imaging method involves acquisition of sets of magnetic resonance signals from several scan-volumes of an object. According to the invention different spatial approaches are taken in the scanning of the respective scan-volumes. In particular_respective scan-volumes include different numbers of scan-slices or scan slices of respective scan-volumes have different slice-thickness or scan-slices of respective scan-volumes have different fields-of-view or scan-slices of respective scan-volumes have different numbers of scanned points in k-space.
    Type: Grant
    Filed: July 10, 2000
    Date of Patent: November 12, 2002
    Assignee: Koninklijke Philips Electronics
    Inventors: Romhild Martijn Hoogeveen, Diana Maria Francisca Geraats, Tim Leiner, Kai Yiu J. A. M. Ho