Patents by Inventor Tim Leiner
Tim Leiner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12089977Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analyzing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.Type: GrantFiled: May 11, 2021Date of Patent: September 17, 2024Assignee: Pie Medical Imaging B.V.Inventors: Ivana Isgum, Majd Zreik, Tim Leiner, Jean-Paul Aben
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Publication number: 20210334963Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analyzing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.Type: ApplicationFiled: May 11, 2021Publication date: October 28, 2021Applicant: Pie Medical Imaging B.V.Inventors: Ivana Isgum, Majd Zreik, Tim Leiner, Jean-Paul Aben
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Patent number: 11004198Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analysing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.Type: GrantFiled: July 11, 2019Date of Patent: May 11, 2021Assignee: Pie Medical Imaging B.V.Inventors: Ivana Isgum, Majd Zreik, Tim Leiner
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Publication number: 20190333216Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analysing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.Type: ApplicationFiled: July 11, 2019Publication date: October 31, 2019Applicant: Pie Medical Imaging B.V.Inventors: Ivana Isgum, Majd Zreik, Tim Leiner
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Patent number: 10395366Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analyzing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.Type: GrantFiled: January 7, 2019Date of Patent: August 27, 2019Assignee: Pie Medical Imaging B.V.Inventors: Ivana Isgum, Majd Zreik, Tim Leiner
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Publication number: 20190139219Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analysing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.Type: ApplicationFiled: January 7, 2019Publication date: May 9, 2019Applicant: Pie Medical Imaging B.V.Inventors: Ivana Isgum, Majd Zreik, Tim Leiner
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Patent number: 10176575Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analyzing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.Type: GrantFiled: March 23, 2018Date of Patent: January 8, 2019Assignee: Pie Medical Imaging B.V.Inventors: Ivana Isgum, Majd Zreik, Tim Leiner
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Publication number: 20180276817Abstract: Methods and systems are provided for assessing the presence of functionally significant stenosis in one or more coronary arteries, further known as a severity of vessel obstruction. The methods and systems can implement a prediction phase that comprises segmenting at least a portion of a contrast enhanced volume image data set into data segments corresponding to wall regions of the target organ, and analysing the data segments to extract features that are indicative of an amount of perfusion experiences by wall regions of the target organ. The methods and systems can obtain a feature-perfusion classification (FPC) model derived from a training set of perfused organs, classify the data segments based on the features extracted and based on the FPC model, and provide, as an output, a prediction indicative of a severity of vessel obstruction based on the classification of the features.Type: ApplicationFiled: March 23, 2018Publication date: September 27, 2018Applicant: UMC Utrecht Holding B.V.Inventors: Ivana Isgum, Majd Zreik, Tim Leiner
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Patent number: 6479996Abstract: A magnetic resonance imaging method involves acquisition of sets of magnetic resonance signals from several scan-volumes of an object. According to the invention different spatial approaches are taken in the scanning of the respective scan-volumes. In particular_respective scan-volumes include different numbers of scan-slices or scan slices of respective scan-volumes have different slice-thickness or scan-slices of respective scan-volumes have different fields-of-view or scan-slices of respective scan-volumes have different numbers of scanned points in k-space.Type: GrantFiled: July 10, 2000Date of Patent: November 12, 2002Assignee: Koninklijke Philips ElectronicsInventors: Romhild Martijn Hoogeveen, Diana Maria Francisca Geraats, Tim Leiner, Kai Yiu J. A. M. Ho