Abstract: An exemplary ablation system is provided. The system is designed for safe and efficacious energy delivery into tissue by, for example, emitting energy in a controlled, repeatable manner that allows for feedback and energy emission titration based on sensed parameters (e.g., tissue temperature) measured during ablation. The system may include a switching antenna for both heating of target tissue and radiometry to monitor the temperature of the heated tissue. For example, the switching antenna may include a monopole formed by proximal and distal radiating elements, such that the proximal radiating element includes a short to defeat a choke action of the proximal radiating element. The system further includes a processor for calculating the temperature of the target tissue and estimating volume of the ablation lesion based on the target tissue temperature.

Abstract: Perfusion systems and methods are provided for increasing peripheral blood flow to reduce limb ischemia, in which an extracorporeal pump having a controller, and catheter/tubing set, employed alone or in conjunction with an interventional or circulatory assist device, withdraws blood from a patient's vasculature and reintroduces that blood at another location within the patient's vasculature at a controlled local pressure or flow rate, without interfering with operation of the interventional or circulatory assist device or surgical intervention.

Abstract: An exemplary ablation system is provided. The system is designed for safe and efficacious energy delivery into tissue by, for example, emitting energy in a controlled, repeatable manner that allows for feedback and energy emission titration based on sensed parameters (e.g., tissue temperature) measured during ablation. The system may include a switching antenna for both heating of target tissue and radiometry to monitor the temperature of the heated tissue. For example, the switching antenna may include a monopole formed by proximal and distal radiating elements, such that the proximal radiating element includes a short to defeat a choke action of the proximal radiating element. The system further includes a processor for calculating the temperature of the target tissue and estimating volume of the ablation lesion based on the target tissue temperature.

Abstract: Perfusion systems and methods are provided for increasing peripheral blood flow to reduce limb ischemia, in which an extracorporeal pump having a controller, and catheter/tubing set, employed alone or in conjunction with an interventional or circulatory assist device, withdraws blood from a patient's vasculature and reintroduces that blood at another location within the patient's vasculature at a controlled local pressure or flow rate, without interfering with operation of the interventional or circulatory assist device or surgical intervention.

Abstract: Perfusion systems and methods are provided for increasing peripheral blood flow to reduce limb ischemia, in which an extracorporeal pump having a controller, and catheter/tubing set, employed alone or in conjunction with an interventional or circulatory assist device, withdraws blood from a patient's vasculature and reintroduces that blood at another location within the patient's vasculature at a controlled local pressure or flow rate, without interfering with operation of the interventional or circulatory assist device or surgical intervention.

Abstract: Systems and methods for measuring and monitoring intracavitary tissue temperature. The system may include a catheter shaft with a circuit board disposed therein, the circuit board having an array of sensors disposed thereon. The catheter shaft may have an opening and an expandable structure surrounding the opening to provide a field of view of the intracavitary tissue for the array of sensors through the opening. The system may include a software-based programming system run on a computer such that a clinician may review information indicative of temperature of the intracavitary tissue, and be alerted if the temperature exceeds a predetermined threshold.

Abstract: Described herein are methods and systems for performing a procedure for ovarian rebalancing. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may also be useful in the treatment of infertility associated with PCOS.

Abstract: Systems and methods for measuring and monitoring intracavitary tissue temperature. The system may include a catheter shaft with a circuit board disposed therein, the circuit board having an array of sensors disposed thereon. The catheter shaft may have an opening and an expandable structure surrounding the opening to provide a field of view of the intracavitary tissue for the array of sensors through the opening. The system may include a software-based programming system run on a computer such that a clinician may review information indicative of temperature of the intracavitary tissue, and be alerted if the temperature exceeds a predetermined threshold.

Abstract: Described herein are methods and systems for performing a procedure for ovarian rebalancing. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may also be useful in the treatment of infertility associated with PCOS.

Abstract: An exemplary ablation system is provided. The system is designed for safe and efficacious energy delivery into tissue by, for example, emitting energy in a controlled, repeatable manner that allows for feedback and energy emission titration based on sensed parameters (e.g., tissue temperature) measured during ablation. The system may include a switching antenna for both heating of target tissue and radiometry to monitor the temperature of the heated tissue. For example, the switching antenna may include a monopole formed by proximal and distal radiating elements, such that the proximal radiating element includes a short to defeat a choke action of the proximal radiating element. The system further includes a processor for calculating the temperature of the target tissue and estimating volume of the ablation lesion based on the target tissue temperature.

Abstract: Systems and methods for measuring and monitoring intracavitary tissue temperature. The system may include a catheter shaft with a circuit board disposed therein, the circuit board having an array of sensors disposed thereon. The catheter shaft may have an opening and an expandable structure surrounding the opening to provide a field of view of the intracavitary tissue for the array of sensors through the opening. The system may include a software-based programming system run on a computer such that a clinician may review information indicative of temperature of the intracavitary tissue, and be alerted if the temperature exceeds a predetermined threshold.

Abstract: Devices and methods for perfusing a patient's vasculature are provided. The device preferably includes a cannula with a port and a retractable sheath disposed over the port of the cannula. When the cannula is positioned within the patient's vasculature, the retractable sheath may be retracted to expose the port to divert blood flow towards another portion of the patient's vasculature, for example, to prevent ischemia of the patient's lower extremities. The device may be used during heart surgery, percutaneous heart or circulatory procedures, or other cardiac interventional procedures and may be used in conjunction with another device such as an extracorporeal membrane oxygenation (“ECMO”) machine.

Abstract: Described herein are methods and systems for performing a procedure for ovarian rebalancing. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may also be useful in the treatment of infertility associated with PCOS.

Abstract: Systems and methods for measuring and monitoring intracavitary tissue temperature. The system may include a catheter shaft with a circuit board disposed therein, the circuit board having an array of sensors disposed thereon. The catheter shaft may have an opening and an expandable structure surrounding the opening to provide a field of view of the intracavitary tissue for the array of sensors through the opening. The system may include a software-based programming system run on a computer such that a clinician may review information indicative of temperature of the intracavitary tissue, and be alerted if the temperature exceeds a predetermined threshold.

Abstract: A system for the treatment of Alzheimer's disease is provided by moving cerebrospinal fluid containing particles know to contribute to onset of Alzheimer's disease from a source of cerebrospinal fluid to the stomach or bladder, where the particles are safely digested by gastric acid or excreted, the system including an implantable pump, an inlet catheter, an outlet catheter, and a one-way valve. The system further includes at least one filter to filter harmful particles from the cerebrospinal fluid and return the filtered cerebrospinal fluid back to the source of cerebrospinal fluid, where the harmful particles blocked by the filter may be rinsed off the filter and transported to the stomach or bladder.

Abstract: Systems and methods for measuring and monitoring intracavitary tissue temperature. The system may include a catheter shaft with a circuit board disposed therein, the circuit board having an array of sensors disposed thereon. The catheter shaft may have an opening and an expandable structure surrounding the opening to provide a field of view of the intracavitary tissue for the array of sensors through the opening. The system may include a software-based programming system run on a computer such that a clinician may review information indicative of temperature of the intracavitary tissue, and be alerted if the temperature exceeds a predetermined threshold.

Abstract: A system for the treatment of Alzheimer's disease is provided by moving cerebrospinal fluid containing particles know to contribute to onset of Alzheimer's disease from a source of cerebrospinal fluid to the stomach or bladder, where the particles are safely digested by gastric acid or excreted, the system including an implantable pump, an inlet catheter, an outlet catheter, and a one-way valve. The system further includes at least one filter to filter harmful particles from the cerebrospinal fluid and return the filtered cerebrospinal fluid back to the source of cerebrospinal fluid, where the harmful particles blocked by the filter may be rinsed off the filter and transported to the stomach or bladder.

Abstract: A system for the treatment of Alzheimer's disease is provided by moving cerebrospinal fluid containing particles know to contribute to onset of Alzheimer's disease from a source of cerebrospinal fluid to the stomach or bladder, where the particles are safely digested by gastric acid or excreted, the system including an implantable pump, an inlet catheter, an outlet catheter, and a one-way valve. The system further includes at least one filter to filter harmful particles from the cerebrospinal fluid and return the filtered cerebrospinal fluid back to the source of cerebrospinal fluid, where the harmful particles blocked by the filter may be rinsed off the filter and transported to the stomach or bladder.

Abstract: A system for the treatment of Alzheimer's disease is provided by moving cerebrospinal fluid containing particles know to contribute to onset of Alzheimer's disease from a source of cerebrospinal fluid to the stomach or bladder, where the particles are safely digested by gastric acid or excreted, the system including an implantable pump, an inlet catheter, an outlet catheter, and a one-way valve. The system further includes at least one filter to filter harmful particles from the cerebrospinal fluid and return the filtered cerebrospinal fluid back to the source of cerebrospinal fluid, where the harmful particles blocked by the filter may be rinsed off the filter and transported to the stomach or bladder.

Abstract: A method for performing cardiovascular and surgical procedures includes providing a conduit in the form of a graft/canula placed using balloon dilatation catheter and providing a fixing mechanism for the graft/canula. At least one opening is formed through a wall of the heart substantially at the apex. The escape of blood is prevented through the use of the fixing mechanism. Each of these steps is performed while the heart is beating.