Abstract: Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: (I) wherein Ring A, Ring B, Ring C, R1, R2, R3, R4, R5, L, m, n, and p are as defined herein. The compounds are modulators of G-protein coupled receptor 88 (GPR88). Also disclosed are pharmaceutical compositions comprising the compounds; and the compounds for use in the treatment of diseases mediated by GPR88, including Tourette's Syndrome, Huntington's Disease (HD), Addiction, Parkinson's Disease (PD), Schizophrenia, Alzheimer's disease, and Attention Deficit Hyperactivity Disorder (ADHD).

Abstract: A biological specimen of a subject is handled and tracked for a procedure involving that specimen. Prior to initiation of the procedure, a first procedure data structure (PDS) is generated. The first PDS binds an identifier corresponding to the subject with an indicator of a procedure to be performed on the specimen and identifiers of a specimen container and a specimen holder that physically contacts the biological specimen, as well as a scheduled time for the procedure. A schedule of a plurality of PDSs including the first PDS, is displayed on a display device of a graphical user interface. Following initiation of the procedure, the first PDS is updated based on user input, and after the procedure, at least a portion of the first PDS, as updated, is stored in a database in conjunction with other PDSs respectively associated with other completed procedures.

Abstract: A system for separating particles or cells by magnetic ratcheting has a vector of spaced apart magnetic bars on a substrate. The system can be used to separate and concentrate magnetic objects based on iron oxide content. For cells, different phenotypes may be separated based on surface expression of proteins or molecules that are bound to magnetic beads. A magnetic field generator generates a cycling magnetic field that acts to separate magnetic particles or cells from non-magnetic particles or cells in a solution.

Abstract: An agricultural vehicle is described having a chassis and a cab mounted on the chassis. A suspension system for reducing the accelerations transmitted from the vehicles tires or tracks through the frame, into the cab, and ultimately through to the operator is provided. By reducing the accelerations, the ride quality is greatly improved, allowing operators to operate a vehicle for longer periods of time without excessive fatigue.

Abstract: An agricultural vehicle is described having a chassis and a cab mounted on the chassis. A suspension system for reducing the accelerations transmitted from the vehicles tires or tracks through the frame, into the cab, and ultimately through to the operator is provided. By reducing the accelerations, the ride quality is greatly improved, allowing operators to operate a vehicle for longer periods of time without excessive fatigue.

Abstract: A light source with an integral surface of revolution to project an emergency warning light signal for a vehicle in a substantially horizontal 360° arc. A centrally positioned mirror assembly has a plurality of light sources spaced about the mirror assembly.