Abstract: Provided herein is a system and method for performing a magnetic resonance imaging scan using a MR scanner. The method can comprise receiving via a user interface a MR imaging protocol categorizable into a MR scan type of a predefined set of MR scan types. Further, the method can comprise querying a database by providing to the database scan information permitting the database to identify the MR scan type of the MR imaging protocol. The method can further comprise receiving from the database statistical information on the MR scan type which can include statistics on modifications of individual scan parameters of the MR scan type, and providing the statistical information to the user interface. Modifications of the MR imaging protocol can be received from the user interface, resulting in a modified MR imaging protocol, according to which the MR imaging scan can be performed.

Abstract: A method for reconstructing a fluorescence image of the interior of a turbid medium is provided. The method comprises the step: accommodating a turbid medium (1) to which a fluorescent contrast agent has been administered in a measurement volume (4). The fluorescent contrast agent is capable of emitting light in a first range of wavelengths upon irradiation with light. The method further comprises: performing attenuation measurements at a plurality of different wavelengths (?i, . . .

Abstract: In optical tomography, a calibration of the data may be necessary for image reconstruction. According to an exemplary embodiment of the present invention, the object of interest is used for calibration, wherein the image data is acquired during a highly oxygenated phase of the object of interest and wherein the calibration data is acquired during a low oxygenated phase of the object of interest. This may provide for an improved calibration, resulting in improved image quality.

Abstract: The invention relates to a method of imaging an interior of a turbid medium, a device for imaging an interior of a turbid medium, and a medical image acquisition device. A turbid medium is accommodated in a receiving volume (5), light from a light source is coupled into (10) and out of the receiving volume and detected (15) after which a dataset is obtained from the detected light (20). The dataset is then communicated to an image reconstruction algorithm (30) and an image of an interior of the turbid medium is reconstructed based on the detected light (35). According to the invention the dataset is changed prior to communicating the dataset to the image reconstruction algorithm into a further dataset (25), with a further dataset satisfying an input assumption underlying the image reconstruction algorithm.

Abstract: The invention relates to a method of determining a spatial distribution of magnetic particles in an examination zone, in which a magnetic field is generated that has a first sub-zone of lower magnetic field strength and a second sub-zone of higher magnetic field strength. The positions of the two sub-zones are changed, as a result of which the magnetization in the examination zone changes. Measured values that depend on the change in magnetization are acquired. A reference response function by means of which measured values can be determined mathematically from a spatial distribution of magnetic particles is then determined by means of at least extensive magnetic specimen distribution. Finally, the spatial distribution of magnetic particles is reconstructed from the measured values by means of the reference response function.

Abstract: A combined magnetic resonance (MR) and radiation therapy system (10) includes a bore-type magnet (12) with a magnet radiation translucent region (16) which allows radiation beams to travel radially through the magnet and a split-type gradient coil (18) includes a gradient coil radiation translucent region (20) aligned to the magnet radiation translucent region (16). A radiation source (24), disposed laterally to the magnet, administers a radiation dose through the magnet and gradient coil radiation translucent regions (16, 20) to an examination region (14). A dosage unit (66) determines the actual radiation dose delivered to each voxel of a target volume (30) and at least one non-target volume based on a pre-treatment, intra-treatment, and/or post-treatment image representation of the target volume (30) and the at least one non-target volume. A planning processor (60) updates at least one remaining radiation dose of a radiation therapy plan based on the determined actual radiation dose.

Abstract: A device for determining a concentration-related quantity of a fluorescent contrast agent applied to an object (2), in particular a turbid medium. Said device generally comprises a source (4) of electromagnetic radiation for irradiating the object (2) at an excitation wavelength and at least one first detecting means (6, 7.1, 7.2, . . . , 8) for detecting fluorescent electromagnetic radiation emitted by the contrast agent at a fluorescence wavelength, said first detecting means producing fluorescence intensity data (F). The proposed device further comprises at least one second detecting means (6, 7.1, 7.2, . . .

Abstract: The invention relates to a projection values processing apparatus (1) for processing acquired projection values. A first image is reconstructed from acquired projection values under consideration of a reconstruction assumption by a reconstruction unit (13). A simulated projection values determining unit (14) determines simulated projection values by simulating a projection through the reconstructed first image under consideration of the reconstruction assumption, and inconsistency values are determined for the acquired projection values by an inconsistency determining unit (15), wherein an inconsistency value is indicative of a degree of inconsistency of a respective acquired projection value with the reconstruction assumption, by comparing the acquired projection values and the simulated projection values.

Abstract: An imaging system for imaging of a turbid medium comprises a radiation source to illuminate an object to be imaged. A detection system detects radiation from the object and includes a separation module which separates and distinguishes radiation components having respective wavelength ranges. An analysis module forms a comparison of respective radiation components. An image dataset is reconstructed on the basis of the comparison of respective radiation components. The comparison may involve the ratio of the levels of the high-wavelength radiation component to the low-wavelength radiation component, the relative difference of the levels of high-wavelength radiation component to the detected radiation, and the relative difference of the levels of the high-wavelength radiation component to the low-wavelength radiation component.

Abstract: A method for reconstructing a fluorescence image of the interior of a turbid medium is provided. The method comprises the step: accommodating a turbid medium (1) to which a fluorescent contrast agent has been administered in a measurement volume (4). The fluorescent contrast agent is capable of emitting light in a first range of wavelengths upon irradiation with light. The method further comprises: performing attenuation measurements at a plurality of different wavelengths (?i, . . .

Abstract: It is an object of the invention to provide spiral computer tomography which has a high image quality. It relates to a reconstruction method for computer tomography of the heart, wherein the image is reconstructed from a data component of recordings of a partial detector path of a detector device and from a data component of recordings of a full detector path of the detector device, and to a computer tomograph having a beam source, a drive arrangement for driving the beam source in a spiral path around an object, a detector device for recording the radiation from the beam source which passes at least partially through the object, and a control device for reconstructing data components of a partial detector path and a full detector path.

Abstract: A method for assessing measurement quality in acquisition of an image of the interior of a medium (1) is provided. The method comprises the steps: subsequently irradiating the medium (1) with light from a plurality of different source positions (s) and, for each source position, detecting light emanating from the medium in a plurality of different detection positions (d) for acquisition of an image of the interior of the medium (1). The method further comprises the step: providing information about whether the measurement quality is deteriorated by exploiting signal symmetry under reversal of the light path.

Abstract: A method for reconstructing a fluorescence image of the interior of a turbid medium is provided. Initial Green's functions for the light propagation in the turbid medium for irradiation light are calculated from the diffusion equation based on an initial assumption for the optical properties of the turbid medium. Optical properties are reconstructed as a function of the position in the interior of the turbid medium based on the results of an attenuation measurement. Updated Green's functions for the light propagation in the turbid medium for irradiation light are calculated from the diffusion equation based on the reconstructed optical properties of the turbid medium. Updated Green's functions for the light propagation in the turbid medium for fluorescence light are calculated from the diffusion equation based on the reconstructed optical properties of the turbid medium and based on an assumed contrast agent distribution.

Abstract: A device (1) for imaging the interior of an optically turbid medium is provided. The device comprises a receptacle (3; 103) structured to accommodate an optically turbid medium for examination and an optically matching medium filling a space between an inner surface (6; 106) of the receptacle (3; 103) and the optically turbid medium. The device comprises at least one light source generating light to be coupled into the receptacle (3; 103) and at least one detector for detecting light emanating from the receptacle (3; 103). A coupling surface (10; 110) optically coupled to the inner surface (6; 106) of the receptacle and a coupling member (11; 111) optically coupled to the light source and the detector are provided.

Abstract: An imaging system for imaging a turbid medium comprises a radiation source to illuminate an object to be imaged. A detection system to detect radiation from the object to produce a plurality of detected radiation levels at respective positions relative to the object. A distinction is made between (i) a central radiation component having passed mainly through an inner region of the object and (ii) a boundary radiation component having passed mainly through a boundary region of the object. On the basis of a comparison of the central radiation component and the boundary radiation component the optical properties, notably optical scattering and optical absorption are derived. From the detected radiation from the object and the optical properties an image of the interior or the object is reconstructed.

Abstract: The invention relates to a method of determining a spatial distribution of magnetic particles in an examination area, in which a magnetic field is generated which has a first part-region having a relatively low magnetic field strength and a second part-region having a relatively high magnetic field strength. The position of the two part-regions is changed, as a result of which the magnetization in the examination area changes, and real measured values which depend on the change in magnetization are recorded. A dependence distribution which depends on a spatial distribution of magnetic particles is then determined such that a sum which comprises as summands a) the difference of the real measured values from fictitious measured values which are determined by applying a transfer function to the dependence distribution, and b) the product of a regularization parameter and of a regularization value which is determined by applying the regularization functional to the dependence distribution, is minimized.

Abstract: The increasing cone angle of current high-end and future CT systems leads to a decrease in image quality if approximate cone-beam reconstruction methods are used. According to an exemplary embodiment of the present invention, an iterative four-dimensional cardiac CT reconstruction is provided, in which phase volumes are selected from the four-dimensional data set, each having the same spatial volume at different phase points. Corresponding voxels inside these phase volumes are then forward projected onto the same projection. After calculation of a different projection, these voxels are updated. This may provide for an efficient implementation of an iterative four-dimensional cardiac cone-beam CT reconstruction.

Abstract: A radiographic imaging apparatus includes a radiation detector (16) and a radiation source (12) which projects a non-parallel beam of radiation into field of view (14). A footprint of each voxel (v) which is projected on the detector (16) is corrected based on the position of the voxel (v) in the field of view (14) in relation to the radiation detector (16) and the radiation source (12). The contributions from substantially parallel redundant projections are further combined based on a fractional distance frac from a center point (82) of the voxel (v) to a center of each of the adjacent redundant projections.

Abstract: The invention relates to a method of imaging an interior of a turbid medium, a device for imaging an interior of a turbid medium, and a medical image acquisition device. A turbid medium is accommodated in a receiving volume (5), light from a light source is coupled into (10) and out of the receiving volume and detected (15) after which a dataset is obtained from the detected light (20). The dataset is then communicated to an image reconstruction algorithm (30) and an image of an interior of the turbid medium is reconstructed based on the detected light (35). According to the invention the dataset is changed prior to communicating the dataset to the image reconstruction algorithm into a further dataset (25), with a further dataset satisfying an input assumption underlying the image reconstruction algorithm.

Abstract: The invention relates to a system, a medical image acquisition system, and a method for imaging an interior of a turbid medium (25). The invention also relates to a marker (60) for use in the method for imaging an interior of a turbid medium (25). The system, the medical image acquisition system, and the method may be used for obtaining an image of an interior of a turbid medium (25) by: accommodation of a turbid medium (25) inside a receiving volume (20); irradiation of the receiving volume (20) with light from a light source; detection of light emanating from the receiving volume (20) as a result of irradiating the receiving volume (20) with light from the light source through the use of a photodetector unit. The detected light is then used to reconstruct an image of an interior of the turbid medium (25).