Patents by Inventor Tim Nielsen
Tim Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150323637Abstract: The invention relates to a method of MR imaging of at least a portion of a body (10) placed in a main magnetic field Bo within the examination volume of a MR device. It is an object of the invention to enable MR imaging with reliable motion detection and high image quality.Type: ApplicationFiled: February 4, 2013Publication date: November 12, 2015Inventors: GABRIELE MARIANNE BECK, TIM NIELSEN, ARJAN WILLEM SIMONETTI, GWENAEL HENRI HERIGAULT, MATHIJS VISSER
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Publication number: 20150212182Abstract: The invention provides for a magnetic resonance imaging system (200, 300) for acquiring magnetic resonance data (242, 244). A processor (230) for controlling the magnetic resonance imaging system executes instructions (250, 252, 254, 256, 258) which cause the processor to repeatedly: control (100) the magnetic resonance imaging system to acquire a portion of the magnetic resonance data, wherein each portion of the magnetic resonance data comprises navigator data (244); create (102) a set of navigator vectors by extracting the navigator data from each portion of the magnetic resonance data; construct (104) a dissimilarity matrix (246, 400, 700, 800, 900, 1000, 1100, 1400, 1500) by calculating a metric between each of the set of navigator vectors; generate (106) a matrix classification (248) of the dissimilarity matrix using a classification algorithm; and control (108) the magnetic resonance imaging system to modify acquisition of the magnetic resonance data using the matrix classification.Type: ApplicationFiled: September 2, 2013Publication date: July 30, 2015Applicant: KONINKLIKE PHILIPS N.V.Inventors: Tim Nielsen, Peter Börnert
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Publication number: 20140348407Abstract: The present invention is directed to a limited angle tomography in combination with a filtered back projection using a special filter operator X. The filter operator X used within the present invention makes it possible to perform region of interest reconstructions although delivering high quality reconstruction images as generated by high effort SART methods. The used filter operator is purely and solely mathematically determined and defined by the spatial geometry which is used for the limited angle tomography. Without having the need to perform several iterations, the present invention directly calculates a solution, i.e. reconstructed image, equivalent to known iteratively construction methods. Although, incomplete projection data p may only be used, the present invention provides for a high image quality.Type: ApplicationFiled: August 27, 2012Publication date: November 27, 2014Applicant: KONINKLIJKE PHILIPS N.V.Inventors: Tim Nielsen, Sebastian Hitziger, Michael Grass
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Patent number: 8666137Abstract: The invention relates to a projection values processing apparatus (1) for processing acquired projection values. A first image is reconstructed from acquired projection values under consideration of a reconstruction assumption by a reconstruction unit (13). A simulated projection values determining unit (14) determines simulated projection values by simulating a projection through the reconstructed first image under consideration of the reconstruction assumption, and inconsistency values are determined for the acquired projection values by an inconsistency determining unit (15), wherein an inconsistency value is indicative of a degree of inconsistency of a respective acquired projection value with the reconstruction assumption, by comparing the acquired projection values and the simulated projection values.Type: GrantFiled: September 1, 2010Date of Patent: March 4, 2014Assignee: Koninklijke Philips N.V.Inventors: Tim Nielsen, Thomas Koehler, Bernhard Brendel
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Publication number: 20140055135Abstract: A magnetic resonance imaging (MRI) system including a memory for storing machine executable instructions and a processor for controlling the magnetic resonance imaging system. The MRI system for performing a plurality of MRI scans for acquiring magnetic resonance data from a target volume of a patient in accordance with respective predefined scan geometries. The execution of the machine executable instructions causes the processor to control the MRI system to at least: perform a first calibration scan; perform a second calibration scan; generate geometry transformation data; determine a deviation of the target volume caused by a movement of the patient; update each of the predefined scan geometries and the second scan geometry as a function of the geometry transformation data; and perform at least one MRI scan of the plurality of MRI scans to acquire image data in accordance with the respective updated predefined scan geometry.Type: ApplicationFiled: August 21, 2013Publication date: February 27, 2014Applicant: KONINKLIJKE PHILIPS N. V.Inventors: Tim NIELSEN, Peter BOERNERT, Julien SENEGAS
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Publication number: 20130265044Abstract: Provided herein is a system and method for performing a magnetic resonance imaging scan using a MR scanner. The method can comprise receiving via a user interface a MR imaging protocol categorizable into a MR scan type of a predefined set of MR scan types. Further, the method can comprise querying a database by providing to the database scan information permitting the database to identify the MR scan type of the MR imaging protocol. The method can further comprise receiving from the database statistical information on the MR scan type which can include statistics on modifications of individual scan parameters of the MR scan type, and providing the statistical information to the user interface. Modifications of the MR imaging protocol can be received from the user interface, resulting in a modified MR imaging protocol, according to which the MR imaging scan can be performed.Type: ApplicationFiled: December 7, 2011Publication date: October 10, 2013Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Julien Senegas, Jens Von Berg, Eric Cohen-Solal, Sebastian Peter Michael Dries, Michael Chun-Chieh Lee, Tim Nielsen, Stefanie Remmele, Torbjorn Vik
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Patent number: 8520921Abstract: A method for reconstructing a fluorescence image of the interior of a turbid medium is provided. The method comprises the step: accommodating a turbid medium (1) to which a fluorescent contrast agent has been administered in a measurement volume (4). The fluorescent contrast agent is capable of emitting light in a first range of wavelengths upon irradiation with light. The method further comprises: performing attenuation measurements at a plurality of different wavelengths (?i, . . .Type: GrantFiled: March 20, 2009Date of Patent: August 27, 2013Assignee: Koninklijke Philips Electronics N.V.Inventors: Ronny Ziegler, Andy Ziegler, Tim Nielsen
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Patent number: 8406840Abstract: In optical tomography, a calibration of the data may be necessary for image reconstruction. According to an exemplary embodiment of the present invention, the object of interest is used for calibration, wherein the image data is acquired during a highly oxygenated phase of the object of interest and wherein the calibration data is acquired during a low oxygenated phase of the object of interest. This may provide for an improved calibration, resulting in improved image quality.Type: GrantFiled: September 7, 2006Date of Patent: March 26, 2013Assignee: Koninklijke Philips Electronics N.V.Inventors: Tim Nielsen, Thomas Koehler
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Patent number: 8374409Abstract: The invention relates to a method of imaging an interior of a turbid medium, a device for imaging an interior of a turbid medium, and a medical image acquisition device. A turbid medium is accommodated in a receiving volume (5), light from a light source is coupled into (10) and out of the receiving volume and detected (15) after which a dataset is obtained from the detected light (20). The dataset is then communicated to an image reconstruction algorithm (30) and an image of an interior of the turbid medium is reconstructed based on the detected light (35). According to the invention the dataset is changed prior to communicating the dataset to the image reconstruction algorithm into a further dataset (25), with a further dataset satisfying an input assumption underlying the image reconstruction algorithm.Type: GrantFiled: December 17, 2007Date of Patent: February 12, 2013Assignee: Koninklijke Philips Electronics N.V.Inventors: Robert Jochemsen, Tim Nielsen
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Patent number: 8355771Abstract: The invention relates to a method of determining a spatial distribution of magnetic particles in an examination zone, in which a magnetic field is generated that has a first sub-zone of lower magnetic field strength and a second sub-zone of higher magnetic field strength. The positions of the two sub-zones are changed, as a result of which the magnetization in the examination zone changes. Measured values that depend on the change in magnetization are acquired. A reference response function by means of which measured values can be determined mathematically from a spatial distribution of magnetic particles is then determined by means of at least extensive magnetic specimen distribution. Finally, the spatial distribution of magnetic particles is reconstructed from the measured values by means of the reference response function.Type: GrantFiled: December 6, 2005Date of Patent: January 15, 2013Assignee: Koninklijke Philips Electronics N.V.Inventors: Bernhard Gleich, Jurgen Weizenecker, Tim Nielsen
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Publication number: 20120184841Abstract: A combined magnetic resonance (MR) and radiation therapy system (10) includes a bore-type magnet (12) with a magnet radiation translucent region (16) which allows radiation beams to travel radially through the magnet and a split-type gradient coil (18) includes a gradient coil radiation translucent region (20) aligned to the magnet radiation translucent region (16). A radiation source (24), disposed laterally to the magnet, administers a radiation dose through the magnet and gradient coil radiation translucent regions (16, 20) to an examination region (14). A dosage unit (66) determines the actual radiation dose delivered to each voxel of a target volume (30) and at least one non-target volume based on a pre-treatment, intra-treatment, and/or post-treatment image representation of the target volume (30) and the at least one non-target volume. A planning processor (60) updates at least one remaining radiation dose of a radiation therapy plan based on the determined actual radiation dose.Type: ApplicationFiled: September 16, 2010Publication date: July 19, 2012Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Tim Nielsen, Peter Boernert, Falk Uhlemann, Johannes Adrianus Overweg
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Patent number: 8204579Abstract: A device for determining a concentration-related quantity of a fluorescent contrast agent applied to an object (2), in particular a turbid medium. Said device generally comprises a source (4) of electromagnetic radiation for irradiating the object (2) at an excitation wavelength and at least one first detecting means (6, 7.1, 7.2, . . . , 8) for detecting fluorescent electromagnetic radiation emitted by the contrast agent at a fluorescence wavelength, said first detecting means producing fluorescence intensity data (F). The proposed device further comprises at least one second detecting means (6, 7.1, 7.2, . . .Type: GrantFiled: June 25, 2007Date of Patent: June 19, 2012Assignee: Koninklijke Philips Electronics N.V.Inventors: Tim Nielsen, Thomas Koehler
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Publication number: 20120148136Abstract: The invention relates to a projection values processing apparatus (1) for processing acquired projection values. A first image is reconstructed from acquired projection values under consideration of a reconstruction assumption by a reconstruction unit (13). A simulated projection values determining unit (14) determines simulated projection values by simulating a projection through the reconstructed first image under consideration of the reconstruction assumption, and inconsistency values are determined for the acquired projection values by an inconsistency determining unit (15), wherein an inconsistency value is indicative of a degree of inconsistency of a respective acquired projection value with the reconstruction assumption, by comparing the acquired projection values and the simulated projection values.Type: ApplicationFiled: September 1, 2010Publication date: June 14, 2012Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Tim Nielsen, Thomas Koehler, Bernhard Brendel
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Patent number: 7986411Abstract: An imaging system for imaging of a turbid medium comprises a radiation source to illuminate an object to be imaged. A detection system detects radiation from the object and includes a separation module which separates and distinguishes radiation components having respective wavelength ranges. An analysis module forms a comparison of respective radiation components. An image dataset is reconstructed on the basis of the comparison of respective radiation components. The comparison may involve the ratio of the levels of the high-wavelength radiation component to the low-wavelength radiation component, the relative difference of the levels of high-wavelength radiation component to the detected radiation, and the relative difference of the levels of the high-wavelength radiation component to the low-wavelength radiation component.Type: GrantFiled: December 12, 2007Date of Patent: July 26, 2011Assignee: Koninklijke Philips Electronics N.V.Inventors: Ronny Ziegler, Tim Nielsen
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Publication number: 20110026851Abstract: A method for reconstructing a fluorescence image of the interior of a turbid medium is provided. The method comprises the step: accommodating a turbid medium (1) to which a fluorescent contrast agent has been administered in a measurement volume (4). The fluorescent contrast agent is capable of emitting light in a first range of wavelengths upon irradiation with light. The method further comprises: performing attenuation measurements at a plurality of different wavelengths (?i, . . .Type: ApplicationFiled: March 20, 2009Publication date: February 3, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Ronny Ziegler, Andy Ziegler, Tim Nielsen
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Patent number: 7856079Abstract: It is an object of the invention to provide spiral computer tomography which has a high image quality. It relates to a reconstruction method for computer tomography of the heart, wherein the image is reconstructed from a data component of recordings of a partial detector path of a detector device and from a data component of recordings of a full detector path of the detector device, and to a computer tomograph having a beam source, a drive arrangement for driving the beam source in a spiral path around an object, a detector device for recording the radiation from the beam source which passes at least partially through the object, and a control device for reconstructing data components of a partial detector path and a full detector path.Type: GrantFiled: November 7, 2005Date of Patent: December 21, 2010Assignee: Koninklijke Philips Electronics N.V.Inventors: Tim Nielsen, Michael Grass
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Publication number: 20100272331Abstract: A method for assessing measurement quality in acquisition of an image of the interior of a medium (1) is provided. The method comprises the steps: subsequently irradiating the medium (1) with light from a plurality of different source positions (s) and, for each source position, detecting light emanating from the medium in a plurality of different detection positions (d) for acquisition of an image of the interior of the medium (1). The method further comprises the step: providing information about whether the measurement quality is deteriorated by exploiting signal symmetry under reversal of the light path.Type: ApplicationFiled: December 10, 2008Publication date: October 28, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Bernhard Johannes Brendel, Tim Nielsen, Levinus Pieter Bakker, Henricus Wilhelm Peter Van Der Heijden
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Publication number: 20100249606Abstract: A method for reconstructing a fluorescence image of the interior of a turbid medium is provided. Initial Green's functions for the light propagation in the turbid medium for irradiation light are calculated from the diffusion equation based on an initial assumption for the optical properties of the turbid medium. Optical properties are reconstructed as a function of the position in the interior of the turbid medium based on the results of an attenuation measurement. Updated Green's functions for the light propagation in the turbid medium for irradiation light are calculated from the diffusion equation based on the reconstructed optical properties of the turbid medium. Updated Green's functions for the light propagation in the turbid medium for fluorescence light are calculated from the diffusion equation based on the reconstructed optical properties of the turbid medium and based on an assumed contrast agent distribution.Type: ApplicationFiled: March 22, 2010Publication date: September 30, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: RONNY ZIEGLER, TIM NIELSEN
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Publication number: 20100238441Abstract: A device (1) for imaging the interior of an optically turbid medium is provided. The device comprises a receptacle (3; 103) structured to accommodate an optically turbid medium for examination and an optically matching medium filling a space between an inner surface (6; 106) of the receptacle (3; 103) and the optically turbid medium. The device comprises at least one light source generating light to be coupled into the receptacle (3; 103) and at least one detector for detecting light emanating from the receptacle (3; 103). A coupling surface (10; 110) optically coupled to the inner surface (6; 106) of the receptacle and a coupling member (11; 111) optically coupled to the light source and the detector are provided.Type: ApplicationFiled: October 13, 2008Publication date: September 23, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Thomas Koehler, Tim Nielsen, Bernhard Brendel, Andy Ziegler, Ronny Ziegler, Levinus Pieter Bakker, Martinus Bernardus Van Der Mark
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Publication number: 20100104149Abstract: An imaging system for imaging a turbid medium comprises a radiation source to illuminate an object to be imaged. A detection system to detect radiation from the object to produce a plurality of detected radiation levels at respective positions relative to the object. A distinction is made between (i) a central radiation component having passed mainly through an inner region of the object and (ii) a boundary radiation component having passed mainly through a boundary region of the object. On the basis of a comparison of the central radiation component and the boundary radiation component the optical properties, notably optical scattering and optical absorption are derived. From the detected radiation from the object and the optical properties an image of the interior or the object is reconstructed.Type: ApplicationFiled: October 8, 2007Publication date: April 29, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Tim Nielsen, Thomas Koehler