Abstract: The present invention relates to methods for detecting a change in chromosomal structure. These methods employ labeled probes that bind nucleic acids. For example, these probes may be comprised of nucleic acids or nucleic acid analogs and a detectable label.

Abstract: An apparatus for processing biological samples comprising means for processing at least one biological sample accommodated on at least one carrier member (15) in a chamber, characterised in that at least one reservoir (18) able to accommodate a fluid is arranged on a surface inside the chamber adjacent to and/or facing a substantial part of the at least one biological sample. Preferably the apparatus comprises a bottom member (12) arranged to support at least one carrier member (15) carrying at least one biological sample and a lid (14) including at least one fluid reservoir (18). The reservoir filled with water provides humidity to the chamber and impedes drying out of the sample.

Abstract: The present invention relates to probes for use in various applications. For example, these probes may be used to detect, quantify, identify, or analyze nucleic acid molecules or other molecules that bind to the probes. The invention also encompasses compositions and kits containing the probes and methods of using the probes.