Patents by Inventor Tim Sattelkau

Tim Sattelkau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation for a cyclohexanecarboxylic acid derivative and intermediates
    Patent number: 8143442
    Abstract: A process for the preparation of a compound of formula (Ia): which are useful as intermediates in the preparation of i.a. pharmaceutically active compounds.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: March 27, 2012
    Assignee: Hoffmann-LA Roche Inc.
    Inventors: Gerard John Harnett, Ursula Hoffmann, Michael Jansen, Reinhard Reents, Tim Sattelkau, Dennis A. Smith, Helmut Stahr
  • Process for the preparation of indoles
    Patent number: 7858811
    Abstract: A process for the preparation of indoles, e.g. 1,2,3,9-tetrahydro-carbazol-4-one and derivatives thereof.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: December 28, 2010
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Bernhard Knipp, Ralf Kucznierz, Tim Sattelkau, Thomas Zeibig
  • Ibandronate polymorph
    Patent number: 7714158
    Abstract: The present invention relates to a new polymorph crystal form of 3-(N-methyl-N-pentyl) amino-1-hydroxypropane-1 1-diphosphonic acid monosodium salt monohydrate (Ibandronate) with the following formula.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: May 11, 2010
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Uwe Eiermann, Bernd Junghans, Bernhard Knipp, Tim Sattelkau
  • PREPARATION FOR A CYCLOHEXANECARBOXYLIC ACID DERIVATIVE AND INTERMEDIATES
    Publication number: 20090253928
    Abstract: A process for the preparation of a compound of formula (Ia): which are useful as intermediates in the preparation of i.a. pharmaceutically active compounds.
    Type: Application
    Filed: March 31, 2009
    Publication date: October 8, 2009
    Inventors: Gerard John Harnett, Ursula Hoffmann, Michael Jansen, Reinhard Reents, Tim Sattelkau, Dennis A. Smith, Helmut Stahr
  • Ibandronate polymorph
    Patent number: 7582789
    Abstract: The present invention relates to a new crystalline polymorph of 3-(N-methyl-N-pentyl) amino-1-hydroxypropane-1,1-diphosphonic acid monosodium salt monohydrate (Ibandronate) with the following formula
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: September 1, 2009
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Uwe Eiermann, Bernd Junghans, Bernhard Knipp, Tim Sattelkau
  • Process for the preparation of indoles
    Publication number: 20070112054
    Abstract: A process for the preparation of indoles, e.g. 1,2,3,9-tetrahydro-carbazol-4-one and derivatives thereof.
    Type: Application
    Filed: November 14, 2006
    Publication date: May 17, 2007
    Inventors: Bernhard Knipp, Ralf Kucznierz, Tim Sattelkau, Thomas Zeibig
  • Tricyclic lactam and sultam derivatives and their use as histone deacetylase inhibitors
    Patent number: 7091229
    Abstract: A compound of formula (I) wherein A and B are optionally substituted cyclohexenyl or phenyl groups, X is carbonyl or sulfonyl, and Y is 5–7 atoms-linker, is useful as histone deacetylase inhibitors, particularly for inhibiting cell proliferation.
    Type: Grant
    Filed: January 24, 2002
    Date of Patent: August 15, 2006
    Assignee: Hoffman-La Roche Inc.
    Inventors: Guy Georges, Adelbert Grossmann, Olaf Mundigl, Wolfgang von der Saal, Tim Sattelkau
  • Ibandronate polymorph
    Publication number: 20060172976
    Abstract: The present invention relates to a new crystalline polymorph of 3-(N-methyl-N-pentyl) amino-1-hydroxypropane -1,1-diphosphonic acid monosodium salt monohydrate (Ibandronate) with the following formula
    Type: Application
    Filed: January 24, 2006
    Publication date: August 3, 2006
    Inventors: Uwe Eiermann, Bernd Junghans, Bernhard Knipp, Tim Sattelkau
  • Ibandronate polymorph
    Publication number: 20060172975
    Abstract: The present invention relates to a new polymorph crystal form of 3-(N-methyl-N-pentyl)amino-1-hydroxypropane-1 1-diphosphonic acid monosodium salt monohydrate (Ibandronate) with the following formula
    Type: Application
    Filed: January 24, 2006
    Publication date: August 3, 2006
    Inventors: Uwe Eiermann, Bernd Junghans, Bernhard Knipp, Tim Sattelkau
  • Aromatic dicarboxylic acid derivatives
    Publication number: 20040214862
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: May 17, 2004
    Publication date: October 28, 2004
    Inventors: Ulrike Leser-Reiff, Tim Sattelkau, Gerd Zimmermann
  • Tetrahydropyridine derivatives, their preparation and their use as cell proliferation inhibitors
    Patent number: 6800638
    Abstract: A compound of the formula (I) wherein A, R1, R2 and X have the meanings defined in the specification, process of manufacturing such as compound and a pharmaceutical composition with HDAC inhibitor activity and anti-cell proliferation activity containing such a compound.
    Type: Grant
    Filed: June 23, 2003
    Date of Patent: October 5, 2004
    Assignee: Hoffman-La Roche Inc.
    Inventors: Guy Georges, Adelbert Grossman, Olaf Mundigl, Wolfgang von der Saal, Tim Sattelkau
  • Aromatic dicarboxylic acid derivatives
    Patent number: 6784173
    Abstract: Compounds of formula I wherein A, R1 and R2 are defined in the specification. These compounds are useful as HDAC inhibitors. Also disclosed are methods of making and using said compounds.
    Type: Grant
    Filed: June 11, 2002
    Date of Patent: August 31, 2004
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ulrike Leser-Reiff, Tim Sattelkau, Gerd Zimmermann
  • Tricyclic lactam and sultam derivatives and their use as histone deacetylase inhibitors
    Publication number: 20040077698
    Abstract: A compound of formula (I) wherein A and B are optionally substituted cyclohexenyl or phenyl groups, X is carbonyl or sulfonyl, and Y is 5-7 atoms-linker, is useful as histone deacetylase inhibitors, particularly for inhibiting cell proliferation.
    Type: Application
    Filed: July 24, 2003
    Publication date: April 22, 2004
    Inventors: Guy Georges, Adelbert Grossmann, Olaf Mundigl, Wolfgang von der Saal, Tim Sattelkau
  • Tetrahydropyridine derivatives, their preparation and their use as cell proliferation inhibitors
    Publication number: 20040053960
    Abstract: A compound of the formula (I) wherein A, R1, R2 and X have the meanings defined in the specification, process of manufacturing such as compound and a pharmaceutical composition with HDAC inhibitor activity and anti-cell proliferation activity containing such a compound.
    Type: Application
    Filed: June 23, 2003
    Publication date: March 18, 2004
    Inventors: Guy Georges, Adelbert Grossman, Olaf Mundigl, Wolfgang von der Saal, Tim Sattelkau
  • Tetralone derivatives
    Patent number: 6531472
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts, wherein R1, R2, R3, R4, R5, X and Y have the meanings defined in the specification. The compounds have histone deacetylase (HDAC) inhibitory activity which is useful in cancer treatment. Also provided is a process for making a compound of formula I by reacting a compound of formula III with a compound of formula IV wherein A is a displaceable group and PG is a protecting group.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: March 11, 2003
    Assignee: Hoffman-La Roche Inc.
    Inventors: Guy Georges, Adelbert Grossmann, Tim Sattelkau, Wolfgang Schaefer, Ulrich Tibes
  • Tricyclic alkylhydroxamate derivatives
    Patent number: 6512123
    Abstract: Compounds of formula I wherein R1, R2, A, X, Y and Z have the meanings provided in the specification, and their enantiomers, diastereoisomers, racemates, pharmaceutically acceptable salts and mixtures thereof. These compounds have HDAC inhibitory activity for inhibiting cell proliferation. Also provided is a process of manufacturing these compounds.
    Type: Grant
    Filed: April 22, 2002
    Date of Patent: January 28, 2003
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Adelbert Grossmann, Wolfgang von der Saal, Tim Sattelkau, Ulrich Tibes
  • Aromatic dicarboxylic acid derivatives
    Publication number: 20030013757
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: June 11, 2002
    Publication date: January 16, 2003
    Inventors: Ulrike Leser-Reiff, Tim Sattelkau, Gerd Zimmermann
  • Tricyclic alkylhydroxamate derivatives
    Publication number: 20020183513
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: April 22, 2002
    Publication date: December 5, 2002
    Inventors: Adelbert Grossmann, Wolfgang von der Saal, Tim Sattelkau, Ulrich Tibes
  • Tetralone derivatives
    Publication number: 20020065282
    Abstract: The present invention provides compounds of formula I 1
    Type: Application
    Filed: December 4, 2001
    Publication date: May 30, 2002
    Inventors: Guy Georges, Adelbert Grossmann, Tim Sattelkau, Wolfgang Schaefer, Ulrich Tibes