Abstract: The invention disclosed herein relates to a device for applying thermal therapy, treatment or comfort to a patient or user which includes a container having an upper side and lower side with a space therebetween containing a chemical composition adapted to provide a thermal effect, and a plurality of discrete attachment areas which generally define a central location in the container. The device has a nest configuration and automatically conforms to the user's geometry upon application of weight thereon. The discrete attachment areas are positioned to define an inner peripheral base portion and outer peripheral portion in the device which collectively form the nest configuration. The device is particularly useful in thermal treatment for infants.