Patents by Inventor Tim Tesmer

Tim Tesmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Barcoding Nucleic Acids
    Publication number: 20210189382
    Abstract: Methods of barcoding nucleic acids, such as genomic DNA, are provided herein. In some embodiments, a fragment of genomic DNA may comprise a first and a second barcode.
    Type: Application
    Filed: February 24, 2021
    Publication date: June 24, 2021
    Inventors: Takao Kurihara, Emmanuel Kamberov, Tim Tesmer, John Langmore
  • Barcoding nucleic acids
    Patent number: 10961529
    Abstract: Methods of barcoding nucleic acids, such as genomic DNA, are provided herein. In some embodiments, a fragment of genomic DNA may comprise a first and a second barcode.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: March 30, 2021
    Assignee: Takara Bio USA, Inc.
    Inventors: Takao Kurihara, Emmanuel Kamberov, Tim Tesmer, John Langmore
  • Methods and compositions for repair of DNA ends by multiple enzymatic activities
    Patent number: 10301660
    Abstract: Provided herein are compositions for and methods of generating ligation-competent nucleic acids. In some aspects, the compositions comprise Exonuclease III, T4 DNA Polymerase, Klenow, and/or T4 polynucleotide kinase.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: May 28, 2019
    Assignee: TAKARA BIO USA, INC.
    Inventors: Emmanuel Kamberov, John Langmore, Tim Tesmer, Marta Gonzalez-Plasky
  • Barcoding Nucleic Acids
    Publication number: 20190153434
    Abstract: Methods of barcoding nucleic acids, such as genomic DNA, are provided herein. In some embodiments, a fragment of genomic DNA may comprise a first and a second barcode.
    Type: Application
    Filed: November 7, 2018
    Publication date: May 23, 2019
    Inventors: Takao Kurihara, Emmanuel Kamberov, Tim Tesmer, John Langmore
  • Barcoding nucleic acids
    Patent number: 10155942
    Abstract: Methods of barcoding nucleic acids, such as genomic DNA, are provided herein. In some embodiments, a fragment of genomic DNA may comprise a first and a second barcode.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: December 18, 2018
    Assignee: Takara Bio USA, Inc.
    Inventors: Takao Kurihara, Emmanuel Kamberov, Tim Tesmer, John Langmore
  • METHODS AND COMPOSITIONS FOR GENERATING AND AMPLIFYING DNA LIBRARIES FOR SENSITIVE DETECTION AND ANALYSIS OF DNA METHYLATION
    Publication number: 20180030527
    Abstract: The present invention regards a variety of methods and compositions for obtaining epigenetic information, such as DNA methylation patterns, through the preparation, amplification and analysis of Methylome libraries.
    Type: Application
    Filed: June 12, 2017
    Publication date: February 1, 2018
    Inventors: Vladimir L. MAKAROV, Emmanuel KAMBEROV, Tong SUN, Jonathan H. PINTER, Brendan J. TARRIER, Eric E. BRUENING, Takao KURIHARA, Tim TESMER, Joseph M'Mwirichia
  • Methods and compositions for generating and amplifying DNA libraries for sensitive detection and analysis of DNA methylation
    Patent number: 9708652
    Abstract: The present invention regards a variety of methods and compositions for obtaining epigenetic information, such as DNA methylation patterns, through the preparation, amplification and analysis of Methylome libraries.
    Type: Grant
    Filed: April 9, 2013
    Date of Patent: July 18, 2017
    Assignee: RUBICON GENOMICS, INC.
    Inventors: Vladimir L. Makarov, Emmanuel Kamberov, Tong Sun, Jonathan H. Pinter, Brendan J. Tarrier, Eric E. Bruening, Takao Kurihara, Tim Tesmer, Joseph M'Mwirichia
  • METHODS AND COMPOSITIONS FOR REPAIR OF DNA ENDS BY MULTIPLE ENZYMATIC ACTIVITIES
    Publication number: 20160289723
    Abstract: Provided herein are compositions for and methods of generating ligation-competent nucleic acids. In some aspects, the compositions comprise Exonuclease III, T4 DNA Polymerase, Klenow, and/or T4 polynucleotide kinase.
    Type: Application
    Filed: March 30, 2016
    Publication date: October 6, 2016
    Applicant: Rubicon Genomics, Inc.
    Inventors: Emmanuel KAMBEROV, John LANGMORE, Tim TESMER, Marta GONZALEZ-PLASKY
  • DEGRADABLE ADAPTORS FOR BACKGROUND REDUCTION
    Publication number: 20160257985
    Abstract: The present disclosure provides systems, processes, articles of manufacture, and compositions that relate to the use of degradable adaptors for background reduction in various nucleic acid manipulations. In particular, adaptors are provided that can be degraded to an extent that the degradation products are incapable or are substantially incapable from participating in subsequent reactions, such as ligation, primer extension, amplification, and sequencing reactions.
    Type: Application
    Filed: November 18, 2014
    Publication date: September 8, 2016
    Applicant: RUBICON GENOMICS, INC.
    Inventors: Emmanuel Kamberov, John Langmore, Tim Tesmer
  • BARCODING NUCLEIC ACIDS
    Publication number: 20150284712
    Abstract: Methods of barcoding nucleic acids, such as genomic DNA, are provided herein. In some embodiments, a fragment of genomic DNA may comprise a first and a second barcode.
    Type: Application
    Filed: November 5, 2013
    Publication date: October 8, 2015
    Applicant: Rubicon Genomics, Inc.
    Inventors: Takao Kurihara, Emmanuel Kamberov, Tim Tesmer, John Langmore
  • Methods and compositions for generating and amplifying DNA libraries for sensitive detection and analysis of DNA methylation
    Patent number: 8440404
    Abstract: The present invention regards a variety of methods and compositions for obtaining epigenetic information, such as DNA methylation patterns, through the preparation, amplification and analysis of Methylome libraries.
    Type: Grant
    Filed: March 3, 2005
    Date of Patent: May 14, 2013
    Assignee: Rubicon Genomics
    Inventors: Vladimir L. Makarov, Emmanuel Kamberov, Tong Sun, Jonathon H. Pinter, Brendan J. Tarrier, Eric E. Bruening, Takao Kurihara, Tim Tesmer, Joseph M'Mwirichia
  • Methods and compositions for generating and amplifying DNA libraries for sensitive detection and analysis of DNA methylation
    Publication number: 20050202490
    Abstract: The present invention regards a variety of methods and compositions for obtaining epigenetic information, such as DNA methylation patterns, through the preparation, amplification and analysis of Methylome libraries. In several aspects of the present invention, there are methods based on methylation-dependent enrichment or depletion of genomic DNA isolated from cellular and cell-free sources. In additional embodiments, there are methods and compositions for single-step high throughput preparations of Methylome libraries.
    Type: Application
    Filed: March 3, 2005
    Publication date: September 15, 2005
    Inventors: Vladimir Makarov, Emmanuel Kamberov, Tong Sun, Jonathon Pinter, Brendan Tarrier, Eric Bruening, Takao Kurihara, Tim Tesmer, Joseph M'Mwirichia