Patents by Inventor Tim Tolker-Nielsen

Tim Tolker-Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12114659
    Abstract: The invention relates to a method for controlling of a biofilm, for removing a formed biofilm and/or for controlling a growth of microorganisms, preferably bacteria, in an aqueous environment of an industrial manufacturing process comprising cellulosic fibre material. In the method a composition comprising a compound selected from a group consisting of 3-[(4-methylphenyl)sulphonyl]-2-propenenitrile and 4-amino-N-2-thiazolyl-benzenesulphonamide is administered to the aqueous environment of the process.
    Type: Grant
    Filed: July 26, 2022
    Date of Patent: October 15, 2024
    Assignees: Kemira Oyj, University of Copenhagen
    Inventors: Jaakko Simell, Marko Kolari, Michael Givskov, Tim Tolker-Nielsen, Morten Levin Rybtke, Jens Bo Andersen
  • Publication number: 20230321043
    Abstract: The present invention relates to c-di-GMP lowering chemical compounds having anti- biofilm properties. In particular, the present invention relates to anti-biofilm compounds or salts or tautomers thereof for use in treatment and/or prevention of bacterial biofilm infection in human subjects caused by biofilm-forming bacteria of the genus Pseudomonas, in particular Pseudomonas spp. including P. aeruginosa. Methods of treating such infections in human subjects are contemplated as well. The present inventions further relates to the use of an anti-biofilm compound or a salt or tautomer thereof for dispersing biofilms in industrial water systems.
    Type: Application
    Filed: August 27, 2021
    Publication date: October 12, 2023
    Inventors: Michael Givskov, Tim Tolker-Nielsen, Jens Bo Andersen, Tim Holm-Jakobsen, Louise Dahl Hultqvist, Carl Martin Peter Nilsson, Thomas Eiland Nielsen, Katrine Qvortrup
  • Publication number: 20220361497
    Abstract: The invention relates to a method for controlling of a biofilm, for removing a formed biofilm and/or for controlling a growth of microorganisms, preferably bacteria, in an aqueous environment of an industrial manufacturing process comprising cellulosic fibre material. In the method a composition comprising a compound selected from a group consisting of 3-[(4-methylphenyl)sulphonyl]-2-propenenitrile and 4-amino-N-2-thiazolyl-benzenesulphonamide is administered to the aqueous environment of the process.
    Type: Application
    Filed: July 26, 2022
    Publication date: November 17, 2022
    Inventors: Jaakko Simell, Marko Kolari, Michael Givskov, Tim Tolker-Nielsen, Morten Levin Rybtke, Jens Bo Andersen
  • Patent number: 11490621
    Abstract: Disclosed is a method for controlling a biofilm, for removing a formed biofilm and/or for controlling a growth of microorganisms, preferably bacteria, in an aqueous environment of an industrial manufacturing process including cellulosic fibre material. In the method, a composition including a compound selected from a group consisting of 3-[(4-methylphenyl)sulphonyl]-2-propenenitrile and 4-amino-N-2-thiazolyl-benzenesulphonamide is administered to the aqueous environment of the process.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: November 8, 2022
    Assignees: Kemira Oyj, University of Copenhagen
    Inventors: Jaakko Simell, Marko Kolari, Michael Givskov, Tim Tolker-Nielsen, Morten Levin Rybtke, Jens Bo Andersen
  • Publication number: 20210127677
    Abstract: Disclosed is a method for controlling a biofilm, for removing a formed biofilm and/or for controlling a growth of microorganisms, preferably bacteria, in an aqueous environment of an industrial manufacturing process including cellulosic fibre material. In the method, a composition including a compound selected from a group consisting of 3-[(4-methylphenyl)sulphonyl]-2-propenenitrile and 4-amino-N-2-thiazolyl-benzenesulphonamide is administered to the aqueous environment of the process.
    Type: Application
    Filed: August 28, 2018
    Publication date: May 6, 2021
    Applicants: Kemira Oyj, University of Copenhagen
    Inventors: Jaakko Simell, Marko Kolari, Michael Givskov, Tim Tolker-Nielsen, Morten Levin Rybtke, Jens Bo Andersen
  • Publication number: 20160220736
    Abstract: The present invention relates to modified polymer surfaces capable of releasing bioactive agents and a method for preventing cell growth on a surface. Thus, one aspect of the invention relates to a medical device comprising a device substrate having a surface, a polymer coating attached to said surface, and a bioactive agent covalently attached to said polymer coating, and wherein said bioactive agent is covalently attached to said polymer coating via at least one ester or carboxylic acid anhydride moiety sensitive to cleavage by an enzyme. Another aspect of the present invention relates to a method of inhibiting or preventing cell growth on a surface comprising modifying said surface with a polymer coating comprising a bioactive agent covalently attached to said polymer coating.
    Type: Application
    Filed: September 3, 2014
    Publication date: August 4, 2016
    Inventors: Thomas Eiland Nielsen, Vitaly V. Komnatnyy, Michael Givskov, Tim Tolker-Nielsen