Patents by Inventor Timo Ylikomi

Timo Ylikomi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A METHOD FOR DRYING CELL-FREE TISSUE EXTRACT IN A HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND A DRIED HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND CELL-FREE TISSUE EXTRACT
    Publication number: 20190343889
    Abstract: The present disclosure relates to method for drying cell-free tissue extract in a hydrogel comprising nanofibrillar cellulose, the method comprising providing a hydrogel comprising nanofibrillar cellulose, providing cell-free tissue extract comprising a mixture of bioactive substances, providing polyethylene glycol, providing trehalose, mixing the hydrogel, the cell-free tissue extract, the polyethylene glycol and the trehalose to obtain a mixture, and freeze drying the mixture to obtain a cell-free tissue extract in the dried hydrogel comprising nanofibrillar cellulose. The present disclosure relates to a dried hydrogel comprising nanofibrillar cellulose, cell-free tissue extract comprising a mixture of bioactive substances, polyethylene glycol and trehalose, wherein the moisture content of the dried hydrogel is 10% (w/w) or less.
    Type: Application
    Filed: December 15, 2017
    Publication date: November 14, 2019
    Inventors: Kari Luukko, Timo Ylikomi, Jertta-Riina Sarkanen
  • Methods and means for soft tissue engineering
    Patent number: 9056084
    Abstract: Cellfree adipose tissue extracts, implants including the same and methods for the preparation thereof. The extracts and implants are capable of inducing adipogenesis and angiogenesis and are, thus, useful in applications including soft tissue repair and engineering and angiogenesis induction, e.g., in wound healing, treatment of burn injuries and ischemic conditions.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: June 16, 2015
    Inventors: Timo Ylikomi, Jertta-Riina Sarkanen
  • IN VITRO CARDIOVASCULAR MODEL
    Publication number: 20140206029
    Abstract: The present invention relates to a tubule forming platform and an in vitro cardiovascular model for use in pharmacological studies. Furthermore, the invention relates to methods for the preparation said platform and model, and to a method of determining a biological activity of a test substance in said platform and cardiovascular model. Still further, the invention relates to an implantable cardiac structure for use in the treatment of cardiac disorders.
    Type: Application
    Filed: June 14, 2012
    Publication date: July 24, 2014
    Applicant: TAMPEREEN YLIOPISTO
    Inventors: Katriina Aalto-Setälä, Tuula Heinonen, Erja Kerkelä, Jertta-Riina Sarkanen, Hanna Vuorenpää, Timo Ylikomi
  • METHODS AND MEANS FOR SOFT TISSUE ENGINEERING
    Publication number: 20110151005
    Abstract: Cellfree adipose tissue extracts, implants including the same and methods for the preparation thereof. The extracts and implants are capable of inducing adipogenesis and angiogenesis and are, thus, useful in applications including soft tissue repair and engineering and angiogenesis induction, e.g., in wound healing, treatment of burn injuries and ischemic conditions.
    Type: Application
    Filed: March 4, 2011
    Publication date: June 23, 2011
    Inventors: Timo YLIKOMI, Jertta-Riina Sarkanen
  • Use of inhibitors of 24-hydroxylase in the treatment of cancer
    Publication number: 20060074109
    Abstract: The present invention relates to a method of treating cancer in a subject. The method comprises administering to a subject suffering from cancer a therapeutically effective amount of a 24-hydroxylase inhibitor. In certain embodiments, the 24-hydroxylase inhibitor can be coadministered with calcitriol.
    Type: Application
    Filed: September 26, 2005
    Publication date: April 6, 2006
    Inventors: William Polvino, Timo Ylikomi, Yan-Ru Lou, Merja Ahonen, Pentti Tuohimaa, Susanna Miettinen