Patents by Inventor Timothy A. Bertram

Timothy A. Bertram has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOLATED RENAL CELLS AND USES THEREOF
    Publication number: 20240108657
    Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
    Type: Application
    Filed: October 10, 2023
    Publication date: April 4, 2024
    Inventors: Sharon C. Presnell, Andrew T. Bruce, Shay M. Wallace, Sumana Choudhury, Russell W. Kelley, Manuel J. Jayo, Jessica J. Reinsch, Patricia D. Tatsumi, Timothy A. Bertram, Eric S. Werdin, Oluwatoyin A. Knight, H. Scott Rapoport, Roger M. Ilagan
  • Bioactive renal cells for the treatment of chronic kidney disease
    Patent number: 11931383
    Abstract: The present invention concerns methods of using bioactive renal cell populations to provide regenerative effects to a native kidney for the treatment of chronic kidney disease.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: March 19, 2024
    Assignee: ProKidney
    Inventors: Deepak Jain, Timothy A. Bertram
  • ENRICHED BIOACTIVE RENAL CELL POPULATIONS, CHARACTERISTICS AND USES THEREOF
    Publication number: 20240003878
    Abstract: Methods of identifying an enriched heterogeneous renal cell population having therapeutic potential, enriched heterogeneous renal cell populations having therapeutic potential and uses for same.
    Type: Application
    Filed: November 12, 2021
    Publication date: January 4, 2024
    Inventors: Timothy A. BERTRAM, Deepak JAIN
  • TREATMENT OF KIDNEY DISEASE IN SUBJECTS WITH KIDNEY AND/OR URINARY TRACT ANOMALIES
    Publication number: 20220202867
    Abstract: Provided herein arm, inter alia, methods, cell populations, and compositions for treating chronic kidney disease in subjects with a congenital anomaly of a kidney and/or urinary tract.
    Type: Application
    Filed: May 1, 2020
    Publication date: June 30, 2022
    Inventors: Timothy Bertram, Deepak Jain
  • SMART SCHEDULING FOR AUTONOMOUS MACHINE OPERATION
    Publication number: 20220129000
    Abstract: This disclosure provides an autonomous machine system having a scheduling controller configured to determine one or more windows of availability over a time period when the autonomous machine is allowed to operate to perform one or more operational tasks; determine a total operation time over the time period; and determine an operating schedule for a work region that assigns one or more operational tasks to the one or more windows of availability based on the total operation time. The autonomous machine may be commanded to operate in the work region according to the operating schedule.
    Type: Application
    Filed: March 19, 2020
    Publication date: April 28, 2022
    Inventors: Ryan Douglas Ingvalson, Alexander Steven Frick, Jason Thomas Kraft, Timothy Bertram Cleveland
  • BIOACTIVE RENAL CELLS FOR THE TREATMENT OF CHRONIC KIDNEY DISEASE
    Publication number: 20220031755
    Abstract: The present invention concerns methods of using bioactive renal cell populations to provide regenerative effects to a native kidney for the treatment of chronic kidney disease.
    Type: Application
    Filed: August 17, 2021
    Publication date: February 3, 2022
    Inventors: Deepak Jain, Timothy A. Bertram
  • COMPOSITIONS COMPRISING CELL-DELIVERED VESICLES AND USES THEREOF
    Publication number: 20210386786
    Abstract: Provided herein are, inter alia, extracellular products (e.g., vesicles such as microvesicles, e.g., exosomes) produced by renal cells (such as bioactive renal cells, e.g., selected renal cells). Methods of altering components (such as miRNAs or proteins) of vesicles produced by cells, as well as methods of producing vesicles comprising various compounds are also included.
    Type: Application
    Filed: August 28, 2019
    Publication date: December 16, 2021
    Inventors: Timothy A. Bertram, Deepak Jain
  • Bioactive renal cells for the treatment of chronic kidney disease
    Patent number: 11123372
    Abstract: The present invention concerns methods of using bioactive renal cell populations to provide regenerative effects to a native kidney for the treatment of chronic kidney disease.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: September 21, 2021
    Assignee: ProKidney
    Inventors: Deepak Jain, Timothy A. Bertram
  • BIOACTIVE RENAL CELLS FOR THE TREATMENT OF CHRONIC KIDNEY DISEASE
    Publication number: 20210283182
    Abstract: The present invention concerns methods of using bioactive renal cell populations to provide regenerative effects to a native kidney for the treatment of chronic kidney disease.
    Type: Application
    Filed: July 29, 2016
    Publication date: September 16, 2021
    Inventors: Deepak Jain, Timothy A. Bertram
  • BIOACTIVE RENAL CELLS
    Publication number: 20210238600
    Abstract: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
    Type: Application
    Filed: February 9, 2021
    Publication date: August 5, 2021
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric S. Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Jr., Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • Bioactive renal cells
    Patent number: 11066666
    Abstract: The present invention concerns bioactive renal cells populations, renal cell constructs, and methods of making and using the same.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: July 20, 2021
    Assignee: inRegen
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • INJECTABLE CELL AND SCAFFOLD COMPOSITIONS
    Publication number: 20200405913
    Abstract: Provided herein are, inter alia, therapeutic formulations containing active agents, such as bioactive cell populations, and methods of making and using the same.
    Type: Application
    Filed: March 26, 2018
    Publication date: December 31, 2020
    Inventors: Deepak Jain, Timothy A. Bertram
  • IMMUNOPRIVILEGED BIOACTIVE RENAL CELLS FOR THE TREATMENT OF KIDNEY DISEASE
    Publication number: 20200216816
    Abstract: Provided herein are, inter alia, compositions and methods for using genetically modified bioactive renal cell populations to provide regenerative effects to a native kidney for the treatment of chronic kidney disease. In certain embodiments, the aim is to effectively provide a “universal donor” immune-privileged renal cell population where gene editing is used to generate a modified allogeneic renal cell population to be administered to patients without immunosuppression.
    Type: Application
    Filed: June 21, 2018
    Publication date: July 9, 2020
    Inventors: Timothy A. BERTRAM, Deepak JAIN
  • ISOLATED RENAL CELLS AND USES THEREOF
    Publication number: 20190117695
    Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
    Type: Application
    Filed: October 15, 2018
    Publication date: April 25, 2019
    Inventors: Sharon C. Presnell, Andrew T. Bruce, Shay M. Wallace, Sumana Choudhury, Russell W. Kelley, Manuel J. Jayo, Jessica J. Reinsch, Patricia D. Tatsumi, Timothy Bertram, Eric S. Werdin, Oluwatoyin A. Knight, H. Scott Rapoport, Roger M. Ilagan
  • Isolated renal cells and uses thereof
    Patent number: 10105392
    Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: October 23, 2018
    Assignee: INREGEN
    Inventors: Sharon C. Presnell, Andrew Bruce, Shay M. Wallace, Sumana Choudhury, Russell W. Kelley, Manuel J. Jayo, Jessica J. Reinsch, Patricia D. Tatsumi, Timothy A. Bertram, Eric S. Werdin, Oluwatoyin A. Knight, H. Scott Rapoport, Roger M. Ilagan
  • BIOACTIVE RENAL CELLS
    Publication number: 20180282726
    Abstract: The present invention concerns bioactive renal cells populations, renal cell constructs, and methods of making and using the same.
    Type: Application
    Filed: March 19, 2018
    Publication date: October 4, 2018
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darrell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • Bioactive renal cells
    Patent number: 10077442
    Abstract: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: September 18, 2018
    Assignee: inRegen
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • Bioactive renal cells
    Patent number: 10030242
    Abstract: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: July 24, 2018
    Assignee: InRegen
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • CELL SCAFFOLD CONSTRUCTS
    Publication number: 20180071074
    Abstract: The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
    Type: Application
    Filed: May 18, 2017
    Publication date: March 15, 2018
    Inventors: John W. Ludlow, Manuel J. Jayo, Joydeep Basu, Timothy A. Bertram, Christopher W. Genheimer, Kelly I. Guthrie, Roger M. Ilagan, Deepak Jain, Oluwatoyin A. Knight, Richard Payne, Sarah F. Quinlan, H. Scott Rapoport, Namrata D. Sangha
  • BIOACTIVE RENAL CELLS FOR THE TREATMENT OF CHRONIC KIDNEY DISEASE
    Publication number: 20180055885
    Abstract: The present invention concerns methods of using bioactive renal cell populations to provide regenerative effects to a native kidney for the treatment of chronic kidney disease.
    Type: Application
    Filed: July 28, 2017
    Publication date: March 1, 2018
    Inventors: Deepak Jain, Timothy A. Bertram