Patents by Inventor Timothy A. Esbenshade

Timothy A. Esbenshade has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating pain
    Patent number: 8940762
    Abstract: The present invention is directed to methods of treating pain by administering a therapeutically effective amount of an ?7 nAChR ligand or a pharmaceutically acceptable salt thereof, to a mammal in need of treatment thereof and to pharmaceutical compositions comprising such a compound or salt.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: January 27, 2015
    Assignee: AbbVie Inc.
    Inventors: Chih-Hung Lee, Michael R. Schrimpf, Timothy A. Esbenshade, Chang Z. Zhu
  • Macrocyclic benzofused pyrimidine derivatives
    Patent number: 8735411
    Abstract: Macrocyclic benzofused pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions and disorders using such compounds and compositions are described herein.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: May 27, 2014
    Assignee: AbbVie Inc.
    Inventors: Robert J. Altenbach, Huaqing Liu, Irene Drizin, Marlon D. Cowart, Neil Wishart, David J. Babinski, Robert J. Gregg, Timothy A. Esbenshade, Gin C. Hsieh, Jorge D. Brioni, Marie P. Honore, Lawrence A. Black, Chen Zhao, Brian D. Wakefield, Kathryn J. Hancock
  • Treatment of schizophrenia and related disorders
    Patent number: 8252801
    Abstract: The invention relates to a method of administering histamine H3 antagonist and an antipsychotic therapeutic agent, compositions comprising a histamine H3 antagonist and an antipsychotic therapeutic agent, and a related article of manufacture.
    Type: Grant
    Filed: June 3, 2010
    Date of Patent: August 28, 2012
    Assignee: Abbott Laboratories
    Inventors: Lynne E. Rueter, Kaitlin E. Browman, Jorge D. Brioni, Marlon D. Cowart, Timothy A. Esbenshade, Gerard B. Fox
  • Method for pain treatment
    Patent number: 7985745
    Abstract: This invention discloses a method of treating pain by administering histamine H4 receptor ligands and compositions comprising the same.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: July 26, 2011
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Robert J. Altenbach, Huaqing Liu, Irene Drizin, Neil Wishart, David J. Babinski, Robert J. Gregg, Arthur A. Hancock, Kathryn J. Hancock, legal representative, Timothy A. Esbenshade, Gin C. Hsieh, Jorge D. Brioni, Marie P. Honore, Lawrence A. Black, Chen Zhao, Brian D. Wakefield
  • Methods for Treating Pain
    Publication number: 20110178121
    Abstract: The present invention is directed to methods of treating pain by administering a therapeutically effective amount of an ?7 nAChR ligand or a pharmaceutically acceptable salt thereof, to a mammal in need of treatment thereof and to pharmaceutical compositions comprising such a compound or salt.
    Type: Application
    Filed: December 22, 2010
    Publication date: July 21, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Chih-Hung Lee, Michael R. Schrimpf, Timothy A. Esbenshade, Chang Z. Zhu
  • Method for Pain Treatment
    Publication number: 20080194538
    Abstract: This invention discloses a method of treating pain by administering histamine H4 receptor ligands and compositions comprising the same.
    Type: Application
    Filed: September 28, 2007
    Publication date: August 14, 2008
    Inventors: Marlon D. Cowart, Robert J. Altenbach, Huaqing Liu, Irene Drizin, Neil Wishart, David J. Babinski, Robert J. Gregg, Arthur A. Hancock, Timothy A. Esbenshade, Gin C. Hsieh, Jorge D. Brioni, Marie P. Honore, Lawrence A. Black, Chen Zhao, Brian D. Wakefield, Kathryn J. Hancock
  • Macrocyclic Benzofused Pyrimidine Derivatives
    Publication number: 20080188452
    Abstract: Macrocyclic benzofused pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions and disorders using such compounds and compositions are described herein.
    Type: Application
    Filed: September 28, 2007
    Publication date: August 7, 2008
    Inventors: Robert J. Altenbach, Huaqing Liu, Irene Drizin, Marlon D. Cowart, Neil Wishart, David J. Babinski, Robert J. Gregg, Arthur A. Hancock, Kathryn J. Hancock, Timothy A. Esbenshade, Gin C. Hsieh, Jorge D. Brioni, Marie P. Honore, Lawrence A. Black, Chen Zhao, Brian D. Wakefield
  • DETERMINATION OF HISTAMINE-3 BIOACTIVITY
    Publication number: 20080159958
    Abstract: The invention relates to an in vivo method for determining the bioactivity of chemical compounds as histamine-3 receptor (H3R) ligands, and provides animal models to determine such bioactivity. The invention further relates to methods for screening therapeutic compounds demonstrating a desired property, using such methods and models described.
    Type: Application
    Filed: December 5, 2007
    Publication date: July 3, 2008
    Applicant: Abbott Laboratories
    Inventors: Richard J. Radek, R. Scott Bitner, Marlon D. Cowart, Jorge D. Brioni, Timothy A. Esbenshade