Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.

Abstract: A bioreactor system for preparing a cardiac organoid chamber and for subsequent testing thereof is described herein and shown in the exemplary drawing figures. The bioreactor system includes a first vessel having a hollow interior and an open top. A first cover is mated with the open top of the first vessel. The first cover has a first opening formed therein. The system further includes a cannula having a lumen that extends from an open first end to an open second end. The cannula is disposed within the first opening of the first cover such that a portion of the cannula lies below the first cover and for insertion into the hollow interior of the first vessel. A porous ring is coupled to the cannula at or proximate the open second end thereof. The system also includes a balloon catheter having an inflatable balloon at a distal end of a catheter shaft. The balloon catheter is adapted to pass through the lumen of the cannula when the balloon is in a deflated state.

Abstract: A glass having from greater than or equal to about 0.1 mol. % to less than or equal to about 20 mol. % Ho2O3, and one or more chromophores selected from V, Cr, Mn, Fe, Co, Ni, Se, Pr, Nd, Er, Yb, and combinations thereof. The amount of Ho2O3 (mol. %) is greater than or equal to 0.7 (CeO2 (mol. %)+Pr2O3 (mol. %)+Er2O3 (mol. %)). The glass can include one or more fluorescent ions selected from Cu, Sn, Ce, Eu, Tb, Tm, and combinations thereof in addition to, or in place of the chromophores. The glass can also include multiple fluorescent ions.

Abstract: A combustor includes an inlet flow conditioner. The inlet flow conditioner includes a sleeve that circumferentially surrounds a portion of a fuel nozzle assembly and that extends from a forward end of a combustion liner to an inner surface of an end cover. The sleeve defines a plurality of apertures circumferentially spaced about the sleeve. A portion of the inner surface of the end cover and the sleeve define a head end volume of the combustor. An inlet to a premix passage of at least one fuel nozzle of the fuel nozzle assembly is disposed within and is in fluid communication with the head end volume.

Abstract: A task scheduling system that can be used to improve task assignment for multiple satellites, and thereby improve resource allocation in the execution of a task. In some implementations, configuration data for one or more satellites is obtained. Multiple objectives corresponding to a task to be performed using the satellites, and resource parameters associated with executing the task to be performed using the satellites are identified. A score for each objective included in the multiple objectives is computed by the terrestrial scheduler based on the resource parameters and the configuration data for the one or more satellites. The multiple objectives are assigned to one or more of the satellites. Instructions are provided to the one or more satellites that cause the one or more satellites to execute the task according to the assignment of the objectives to the one or more satellites.

Abstract: An assembly for removing a bushing is provided including a mandrel having a size and shape similar to the bushing and a receiver having a hollow interior cavity. A fastener extends through an opening formed in both the mandrel and the receiver. A socket attachment has a first opening configured to removably couple to a first end of the fastener and a second opening configured to removably couple to a torque delivery tool. A biasing mechanism arranged adjacent a second end of the fastener is configured to generate a biasing force to drive the mandrel against a bushing in response to a coupling of the socket attachment and the fastener.

Abstract: A pharmaceutical solution for a medication delivery apparatus, especially a metered dose inhaler, is described. The pharmaceutical solution comprises: (a) a liquefied propellant component consisting essentially of and preferably consisting entirely of 1,1-difluoroethane (R-152a); (b) ethanol; and (c) a drug component dissolved in the propellant/ethanol mixture consisting of at least one drug selected from the group consisting of beclomethasone dipropionate (BDP) and fluticasone propionate (FP).

Abstract: The present invention relates to the signaling of channel quality information in a multi-beam transmission system, wherein a plurality of beams are simultaneously transmitted and a plurality of sets of channel quality information are transmitted for controlling independently the transmission rate on the different beams. Determined are beams with a different quality resulting in different effects of errors in the transmissions of the channel quality information for the beams. Said different effects are exploited for reducing a signaling overhead of the channel quality information for the beams.

Abstract: An endcover assembly for a combustor includes an endcover and a fuel nozzle rigidly connected to the endcover. The fuel nozzle includes a plurality of tubes that extends axially through a first plate, a fuel plenum and a second plate where each tube includes an inlet defined upstream of the first plate and an outlet disposed downstream from the second plate. The endcover assembly further includes an inlet flow conditioner having a forward end connected to the endcover and an aft end axially spaced from the forward end. The inlet flow conditioner circumferentially surrounds at least a portion of the fuel nozzle. A support plate is joined to the aft end of the inlet flow conditioner. Each tube of the fuel nozzle extends through a corresponding tube hole defined by the support plate. The fuel nozzle is connected to the support plate.

Abstract: Disclosed herein are methods and systems for treating a waste substance containing perfluoro- and polyfluoroalkyl substances (PFAS). The method includes combining the PFAS with a first amendment in a reactor to create a combination, heating and pressurizing the combination to hydrothermal conditions, and holding the combination at hydrothermal conditions for a holding time sufficient to at least partially mineralize the PFAS to create a treated combination.

Abstract: Described herein are snow removal machines having at least one auxiliary snow moving member. According to some embodiments, the snow removal machines comprise: an auger assembly for directing snow rearwards to be received by a discharge chute, the auger assembly having auger blade(s) coupled to an auger axle for rotation therewith about a first axis defined by the auger axle; an auxiliary snow moving assembly for directing snow rearwards to be received by the discharge chute, the auxiliary snow moving assembly having snow moving member(s) coupled to an auxiliary axle for rotation therewith about a second axis defined by the auxiliary axle, wherein the auxiliary axle is lower and rearwards of the auger axle towards the discharge chute; and an auxiliary drive assembly configured to rotationally couple the auxiliary axle to the auger axle such that rotation of the auxiliary axle is driven by rotation of the auger axle.

Abstract: The present disclosure provides assemblies for cooling a liquid fuel cartridge unit within a combustor head end. In one embodiment, the cooling is accomplished passively as air from the head end air plenum is directed into a cooling channel radially outward of a liquid fuel delivery conduit. In another embodiment, the cooling of the liquid fuel cartridge unit is accomplished actively as air is directed through a first air flow conduit radially inward of the liquid fuel delivery conduit and then redirected through a second air flow conduit radially outward of the liquid fuel delivery conduit.

Abstract: Blockchain-based proof of presentation of content on a media channel, including: generating, upon receiving a request to generate, at least first, second, and third parameters, wherein the first and second parameters are input parameters and the third parameter is calculated as an output parameter of a one-way cryptographic function; generating a first type of block by incorporating the first and third parameters into the first type of block; validating the first type of block and the blockchain; appending the first type of block to the blockchain when both the first type of block and the blockchain are declared valid; and embedding the second parameter into the content that is to be made available on the media channel to produce tainted content.

Abstract: A system for calculating a heat index includes a temperature sensor, a humidity sensor, and at least two microphones. The sensors and microphones are in communication with a microprocessor, and the microprocessor is configured to analyze data from the microphones to estimate wind speed and to calculate a heat index using data from the temperature sensor, humidity sensor and the estimated wind speed.

Abstract: A delivery vehicle with a core surrounded by a digestible polymer shell having a melting and/or softening point above the body temperature of an animal or human, and where the core has a lipid and/or lipophilic active ingredient dispersed in a continuous polymer matrix. The delivery vehicle can be used to release lipid and/or lipophilic active ingredients, such as pharmaceuticals, nutraceuticals, supplements, traditional/herbal medicine, or combinations thereof, after a predetermined lag time following ingestion.

Abstract: A method and system for drawing a stack graph that includes a timeline and one or more stack lines based on a set of event data. A stack line may be associated with an event target and may include one or more event overlays that represent event objects. In one implementation, event overlays may include a visual characteristic that identifies an event source associated with the event object of the event overlay.

Abstract: Articles, such as sanitary tissue products, including fibrous structures, and more particularly articles including fibrous structures having a plurality of fibrous elements wherein the article exhibits differential cellulose content throughout the thickness of the article and methods for making same are provided.

Abstract: Particulate ultra high molecular weight polyethylene (pUHMWPE) are disclosed having an intrinsic viscosity (IV) of at least 4 dl/g, a molecular weight distribution Mw/Mn of less than 4.0, a median particle size D50 of between 50 and 200 ?m, a residual Ti-content of less than 10 ppm, a residual Si-content of less than 50 ppm, and a total ash content of less than 1000 ppm.

Abstract: A wireless communications system is described which comprises a base station, a relay device, and a terminal device. The terminal device is operable to receive from the base station an allocation of uplink resources for transmitting uplink data to the relay device, and to transmit uplink data to the relay device using the uplink resources allocated to the terminal device. The relay device is operable to receive the transmitted uplink data from the terminal device on the allocated resources, to receive an allocation of uplink resources for relaying the received uplink data to the base station, and to transmit the received uplink data to the base station using the uplink resources allocated to the relay device.

Abstract: An IoT hub comprising one or more servers and databases is configured to automatically assign Internet of Things (IoT) enabled devices to IoT solutions based on a subnet to which the IoT devices are connected. A user interface is configured to enable a user to define subnets within the customer's network environment and assign each subnet to an IoT solution. Upon the user setting up an IoT device's network connection to a network device, such as a router, the IoT device transmits its network information to the IoT hub. The IoT hub can then automatically assign the IoT device to a specific IoT solution without further user input or predict which IoT solution to utilize for that IoT device based on known parameters.