Abstract: Exemplary embodiments are disclosed of systems and methods for remotely controlling locomotives with gestures. In an exemplary embodiment, a system is configured for allowing an operator(s) to remotely control operation of a locomotive with gesture(s) made by an operator(s). The system includes at least one processor configured to be operable for visually recognizing gesture(s) made by an operator(s) in one or more images captured by at least one camera. A locomotive control unit is configured to be operable for controlling the operation of the locomotive according to the visually recognized gesture(s) made by the operator(s).

Abstract: The invention relates to compounds of formula (I): or a salt thereof, wherein R1, G, L1, L2, L3, and Y are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are inhibitors of one, or both of, ?v?1 integrin and ?v?6 integrin that are useful for treating fibrosis such as in nonalcoholic steatohepatitis (NASH), idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

Abstract: Exemplary embodiments are disclosed of systems and methods for remotely controlling locomotives with gestures. In an exemplary embodiment, a system is configured for allowing an operator(s) to remotely control operation of a locomotive with gesture(s) made by an operator(s). The system includes at least one processor configured to be operable for visually recognizing gesture(s) made by an operator(s) in one or more images captured by at least one camera. A locomotive control unit is configured to be operable for controlling the operation of the locomotive according to the visually recognized gesture(s) made by the operator(s).

Abstract: Exemplary embodiments are disclosed of systems and methods for remotely controlling locomotives with gestures. In an exemplary embodiment, a system is configured for allowing an operator(s) to remotely control operation of a locomotive with gesture(s) made by an operator(s). The system includes at least one processor configured to be operable for visually recognizing gesture(s) made by an operator(s) in one or more images captured by at least one camera. A locomotive control unit is configured to be operable for controlling the operation of the locomotive according to the visually recognized gesture(s) made by the operator(s).

Abstract: Apparatus uses engineered collection media to recover mineral particles in a mineral extraction process, e.g., for processing a tailings stream at the end of a flotation separation process. The engineered collection media are added to slurry/tailings containing the mineral particles. The engineered collection media have collection surfaces coated with a chemical selected for attracting the mineral particles to the collection surfaces so the engineered collection media becomes mineral laden media in the slurry/tailings in a loading stage. The apparatus include three stages: removing unwanted material from mineral laden media; using a stripping agent to strip the mineral particles from the mineral laden media; and separating the engineered collection media from the mineral particles and the stripping agent. The stripping agent is reused for stripping, and the engineered collection media are returned to the loading stage. The engineered collection media can have a smooth or foam-like surface.

Abstract: Apparatus uses engineered collection media to recover mineral particles in a mineral extraction process, e.g., for processing a tailings stream at the end of a flotation separation process. The engineered collection media are added to slurry/tailings containing the mineral particles. The engineered collection media have collection surfaces coated with a chemical selected for attracting the mineral particles to the collection surfaces so the engineered collection media becomes mineral laden media in the slurry/tailings in a loading stage. The apparatus include three stages: removing unwanted material from mineral laden media; using a stripping agent to strip the mineral particles from the mineral laden media; and separating the engineered collection media from the mineral particles and the stripping agent. The stripping agent is reused for stripping, and the engineered collection media are returned to the loading stage. The engineered collection media can have a smooth or foam-like surface.

Abstract: Apparatus uses engineered collection media to recover mineral particles in a mineral extraction process, e.g., for processing a tailings stream at the end of a flotation separation process. The engineered collection media are added to slurry/tailings containing the mineral particles. The engineered collection media have collection surfaces coated with a chemical selected for attracting the mineral particles to the collection surfaces so the engineered collection media becomes mineral laden media in the slurry/tailings in a loading stage. The apparatus include three stages: removing unwanted material from mineral laden media; using a stripping agent to strip the mineral particles from the mineral laden media; and separating the engineered collection media from the mineral particles and the stripping agent. The stripping agent is reused for stripping, and the engineered collection media are returned to the loading stage. The engineered collection media can have a smooth or foam-like surface.

Abstract: A hand tool having hinged nipping or cutting blades and handles that are squeezed to effect the cutting or nipping action, at least one of the handles being profiled in cross section to accept and retain a slide-on cushion.

Abstract: A hand tool having hinged nipping or cutting blades and handles that are squeezed to effect the cutting or nipping action, at least one of the handles being profiled in cross section to accept and retain a slide-on cushion.

Abstract: An apparatus for measuring velocity of a fluid passing through a pipe is provided. The apparatus includes a spatial array of sensors having at least two sensors disposed at different axial locations along the pipe, wherein the sensors provide at least one signal indicative of a stochastic parameter associated with a characteristic of the fluid, wherein the characteristic includes at least one of unsteady temperature, density, consistency, transparency, conductivity, capacitance, resistivity, and inductance. A signal processor is also provided, wherein the signal processor is configured to receive the at least one signal and determine the velocity of the fluid using the at least one signal.

Abstract: An apparatus for measuring at least one parameter associated with a fluid flowing within a pipe includes a single sheet of piezoelectric film material wrapped around at least a portion of the pipe and an array of sensors disposed at different locations on the film material. Each of the sensors provides a signal indicative of pressure within the pipe at a corresponding axial and/or circumferential location of the pipe. The sensors are selectively configurable to provide the pressure signals. The signals are processed to determine the parameter. The array of sensors is configurable in response to different criteria. The criteria includes at least one of the parameter of the fluid to be output, an input signal specifying sensors to be selected, a predetermined configuration based on the parameter to be determined, and in response to a previously determined parameter of the fluid.

Abstract: A method and apparatus for measuring a parameter of a flow passing through a pipe is provided, wherein the apparatus includes at least two spatial array of sensors disposed at different axial locations along the pipe, wherein each of the sensors provide a signal indicative of unsteady pressure created by coherent structures convecting with the flow within the pipe at a corresponding axial location of the pipe. The apparatus also includes a signal processor configured to determine the flow rate at the circumference location of each sensor array in response to the respective measured unsteady pressures. The signal processor compares the velocity of the flow at each respective location and provides a signal indicative the presence of solids settled at the bottom of the pipe and/or the level of the settled solids in the pipe, in response to an uncharacteristic increase in the velocity of a lower portion of the flow in comparison to the velocity measured above the lower portion of the flow.

Abstract: An apparatus for measuring velocity of a fluid passing through a pipe is provided. The apparatus includes a spatial array of sensors having at least two sensors disposed at different axial locations along the pipe, wherein the sensors provide at least one signal indicative of a stochastic parameter associated with a characteristic of the fluid, wherein the characteristic includes at least one of unsteady temperature, density, consistency, transparency, conductivity, capacitance, resistivity, and inductance. A signal processor is also provided, wherein the signal processor is configured to receive the at least one signal and determine the velocity of the fluid using the at least one signal.

Abstract: A method and apparatus for determining at least one characteristic of a fluid flowing within a pipe is provided and includes at least one sensing device. The at least one sensing device includes a first sensor segment having a first segment polarity and being associated with a first outer portion of the pipe and a second sensor segment having a second segment polarity and being associated with a second outer portion of the pipe, wherein the first sensor segment and the second sensor segment generate sensor data responsive to the fluid flowing within the pipe. The apparatus further includes a processing device communicated with the at least one sensing device, wherein the processing device receives the sensor data and processes the sensor data to determine the at least one characteristic of the fluid.

Abstract: A apparatus 10,110,170 is provided that measures the speed of sound and/or vortical disturbances propagating in a single phase fluid flow and/or multiphase mixture to determine parameters, such as mixture quality, particle size, vapor/mass ratio, liquid/vapor ratio, mass flow rate, enthalpy and volumetric flow rate of the flow in a pipe, by measuring acoustic and/or dynamic pressures. The apparatus includes a spatial array of unsteady pressure sensors 15-18 placed at predetermined axial locations x1-xN disposed axially along the pipe 14. The pressure sensors 15-18 provide acoustic pressure signals P1(t)-PN(t) to a signal processing unit 30 which determines the speed of sound amix propagating through of the process flow 12 flowing in the pipe 14. The pressure sensors are piezoelectric film sensors that are mounted or clamped onto the outer surface of the pipe at the respective axial location.

Abstract: Methods and systems for enabling and supporting patient compliance with a health treatment program or with health-related instructions from a caregiver are described. An interactive feedback loop is implemented that enhances and improves on present methods of monitoring and supporting patient compliance with treatment programs, particularly for patients with chronic conditions. A patient enters various types of data (e.g., biometric readings, diary entries, responses to surveys and health assessments, etc.) to a health data management system that includes a patient compliance monitoring system. The patient is encouraged to enter as much data as is practical and as frequently as possible. The feedback loop of the present invention provides compliance messages to the patient in a timely manner that are responsive to the data entered by the patient. The messages are customized, supportive, and timely.

Abstract: An apparatus and method of processing flow meter data to filter out signal noise is provided. The method includes defining the flow meter data is a k-? plane, wherein the k-? plane includes a first k-plane quadrant separated from a second k-plane quadrant by a predetermined axis. The flow meter data includes a first data set disposed within the first k-plane quadrant and a second data set disposed within the second k-plane quadrant. The first data set and the second data set are disposed symmetrically about the predetermined axis and subtracting the first data set from the second data set to obtain a resultant data set.

Abstract: A large diameter optical waveguide, grating, and laser includes a waveguide 10 having at least one core 12 surrounded by a cladding 14, the core propagating light in substantially a few transverse spatial modes; and having an outer waveguide dimension d2 of said waveguide being greater than about 0.3 mm. At least one Bragg grating 16 may be impressed in the waveguide 10. The waveguide 10 may be axially compressed which causes the length L of the waveguide 10 to decrease without buckling. The waveguide 10 may be used for any application where a waveguide needs to be compression tuned, e.g., compression-tuned fiber gratings and lasers or other applications. Also, the waveguide 10 exhibits lower mode coupling from the core 12 to the cladding 14 and allows for higher optical power to be used when writing gratings 16 without damaging the waveguide 10. The shape of the waveguide 10 may have other geometries (e.g.

Abstract: There is described a method for converting oripavine to hydromorphone or a physiologically acceptable salt thereof such as hydromorphone hydrochloride involving generation of 8,14-dihydrooripavine utilising diimine.

Abstract: The present invention is concerned with methods for improved production of reticuline. More particularly, the present invention relates to the use of a mutagenized Papaver somniferum poppy plant to produce (S)-reticuline in higher yield. The invention also relates to methods for extracting and purifying reticuline.