Patents by Inventor Timothy Beech

Timothy Beech has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING
    Publication number: 20240327909
    Abstract: Embodiments of the present application relates to methods and compositions for increasing fluorescent dye signal intensity during sequencing by synthesis. In particular, the compositions and methods described herein involve the use aqueous scan mixtures including one or more water-soluble macrocycles that can form host-guest complexes with the dyes.
    Type: Application
    Filed: March 27, 2024
    Publication date: October 3, 2024
    Inventors: Xiaolin Wu, Pietro Gatti Lafranconi, Timothy Beech, Carlo Bravin, Benedict Mackworth, Thomas Tongue, Philip Balding
  • PALLADIUM CATALYST COMPOSITIONS AND METHODS FOR SEQUENCING BY SYNTHESIS
    Publication number: 20240247311
    Abstract: The present application relates to palladium catalyst composition and uses in sequencing by synthesis. In particular, the Pd catalyst composition comprises one or more macrocycles (e.g., cyclodextrin or analogs thereof) as additives for improving thermal or oxidative stability of the active Pd(0) species.
    Type: Application
    Filed: December 20, 2023
    Publication date: July 25, 2024
    Inventors: Cassio Pedroso, Adyasha Panigrahi, Angelica Mariani, Adam Carver, Raphaëlle Hours, Preeti Chandrachud, Antoine Francais, Tushar Apsunde, Kathryn Hattingh, Timothy Beech, Daniel Solis, Elliot J. Lawrence
  • TRANSITION-METAL CATALYST COMPOSITIONS AND METHODS FOR SEQUENCING BY SYNTHESIS
    Publication number: 20240229131
    Abstract: The present application relates to compositions and methods for sequencing by synthesis. A blocking group of a nucleotide may be removed by a transition metal catalyst, the transition metal catalyst activated by a non-reducing ligand and a reducing agent.
    Type: Application
    Filed: December 20, 2023
    Publication date: July 11, 2024
    Inventors: Angelica Mariani, Timothy Beech, Antoine Francais, Adyasha Panigrahi, Kathryn Hattingh, Elena Cressina