Patents by Inventor Timothy Bell
Timothy Bell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240068924Abstract: A method for enhancing gating performance of a cell sorter to prepare an enriched specimen for optical tomography cell analysis includes introducing a specimen into a FACS to generate 2D event data; generating a first scatterplot of the 2D data; identifying target objects; constructing a boundary within the first scatterplot to produce a first gate; counting target objects within the first gate; comparing the number of target objects within the first gate to a first predetermined value and adjusting the first gate as necessary. A boundary around a set of target objects is constructed in a second scatterplot to produce a subset second gate and target objects within the second gate are counted and the count compared to a second predetermined value. When a boundary around target objects meets specifications the first and second gates are stored in memory and used to enrich patient specimens.Type: ApplicationFiled: August 29, 2022Publication date: February 29, 2024Inventors: Daniel J. Sussman, Timothy Bell, Frances Ginn Howard, Jonus Reyna
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Patent number: 11827070Abstract: A mounting apparatus for vehicle suspension ball joints that are firmly affixed for operation, are easily adjustable in a generally vertical direction for precise tuning of suspension geometry for dynamic performance in multiple axes using an array of cylindrical shims tuned to match fastener distance and height with a socket that has mounting bolts that engage a scalloped cap.Type: GrantFiled: December 30, 2021Date of Patent: November 28, 2023Assignee: Maverick Undercar Performance, Inc.Inventors: Timothy Bell, Steve Strasburg
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Publication number: 20230289407Abstract: A method for a system and method for morphometric detection of malignancy associated change (MAC) is disclosed including the acts of obtaining a sample; imaging cells to produce 3D cell images for each cell; measuring a plurality of different structural biosignatures for each cell from its 3D cell image to produce feature data; analyzing the feature data by first using cancer case status as ground truth to supervise development of a classifier to test the degree to which the features discriminate between cells from normal or cancer patients; using the analyzed feature data to develop classifiers including, a first classifier to discriminate normal squamous cells from normal and cancer patients, a second classifier to discriminate normal macrophages from normal and cancer patients, and a third classifier to discriminate normal bronchial columnar cells from normal and cancer patients.Type: ApplicationFiled: December 12, 2022Publication date: September 14, 2023Inventors: Michael G. Meyer, Laimonas Kelbauskas, Rahul Katdare, Daniel J. Sussman, Timothy Bell, Alan C. Nelson
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Patent number: 11551043Abstract: A method for a system and method for morphometric detection of malignancy associated change (MAC) is disclosed including the acts of obtaining a sample; imaging cells to produce 3D cell images for each cell; measuring a plurality of different structural biosignatures for each cell from its 3D cell image to produce feature data; analyzing the feature data by first using cancer case status as ground truth to supervise development of a classifier to test the degree to which the features discriminate between cells from normal or cancer patients; using the analyzed feature data to develop classifiers including, a first classifier to discriminate normal squamous cells from normal and cancer patients, a second classifier to discriminate normal macrophages from normal and cancer patients, and a third classifier to discriminate normal bronchial columnar cells from normal and cancer patients.Type: GrantFiled: February 28, 2019Date of Patent: January 10, 2023Assignee: VISIONGATE, INC.Inventors: Michael G. Meyer, Laimonas Kelbauskas, Rahul Katdare, Daniel J. Sussman, Timothy Bell, Alan C. Nelson
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Publication number: 20220336073Abstract: To enable detection of a plurality of capsule ingestions, the ingestible capsules include a transmitter and processing hardware to generate and transmit the signals. Each ingestible capsule obtains a serial number for distinguishing between the ingestible capsules, and generates a signal indicating that the capsule has been ingested. The signal includes a series of pulses having a particular pulse space and indicating the serial number. Each ingestible capsule transmits the signal to a receiver via the transmitter, where each ingestible capsule is identified based on at least one of: the particular pulse space and the serial number for the ingestible capsule.Type: ApplicationFiled: March 22, 2022Publication date: October 20, 2022Inventors: Brent Arnold Myers, Perry Frogge, Timothy Bell, Eric Buffkin
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Patent number: 11428692Abstract: A method for enhancing gating performance of a cell sorter to prepare an enriched specimen for optical tomography cell analysis includes introducing a specimen into a FACS to generate 2D event data; generating a first scatterplot of the 2D data; identifying target objects; constructing a boundary within the first scatterplot to produce a first gate; counting target objects within the first gate; comparing the number of target objects within the first gate to a first predetermined value and adjusting the first gate as necessary. A boundary around a set of target objects is constructed in a second scatterplot to produce a subset second gate and target objects within the second gate are counted and the count compared to a second predetermined value. When a boundary around target objects meets specifications the first and second gates are stored in memory and used to enrich patient specimens.Type: GrantFiled: July 11, 2018Date of Patent: August 30, 2022Inventors: Daniel J. Sussman, Timothy Bell, Frances Ginn Howard, Jonus Reyna
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Publication number: 20220203789Abstract: A mounting apparatus for vehicle suspension ball joints that are firmly affixed for operation, are easily adjustable in a generally vertical direction for precise tuning of suspension geometry for dynamic performance in multiple axes using an array of cylindrical shims tuned to match fastener distance and height with a socket that has mounting bolts that engage a scalloped cap.Type: ApplicationFiled: December 30, 2021Publication date: June 30, 2022Applicant: Maverick Undercar Performance, Inc.Inventors: Timothy Bell, Steve Strasburg
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Publication number: 20210049425Abstract: A method for a system and method for morphometric detection of malignancy associated change (MAC) is disclosed including the acts of obtaining a sample; imaging cells to produce 3D cell images for each cell; measuring a plurality of different structural biosignatures for each cell from its 3D cell image to produce feature data; analyzing the feature data by first using cancer case status as ground truth to supervise development of a classifier to test the degree to which the features discriminate between cells from normal or cancer patients; using the analyzed feature data to develop classifiers including, a first classifier to discriminate normal squamous cells from normal and cancer patients, a second classifier to discriminate normal macrophages from normal and cancer patients, and a third classifier to discriminate normal bronchial columnar cells from normal and cancer patients.Type: ApplicationFiled: February 28, 2019Publication date: February 18, 2021Applicant: VISIONGATE, INC.Inventors: Michael G. Meyer, Laimonis Kelbauskas, Rahul Katdare, Daniel J. Sussman, Timothy Bell, Alan C. Nelson
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Publication number: 20200018704Abstract: A method for enhancing gating performance of a cell sorter to prepare an enriched specimen for optical tomography cell analysis includes introducing a specimen into a FACS to generate 2D event data; generating a first scatterplot of the 2D data; identifying target objects; constructing a boundary within the first scatterplot to produce a first gate; counting target objects within the first gate; comparing the number of target objects within the first gate to a first predetermined value and adjusting the first gate as necessary. A boundary around a set of target objects is constructed in a second scatterplot to produce a subset second gate and target objects within the second gate are counted and the count compared to a second predetermined value. When a boundary around target objects meets specifications the first and second gates are stored in memory and used to enrich patient specimens.Type: ApplicationFiled: July 11, 2018Publication date: January 16, 2020Applicant: VISIONGATE, INC.Inventors: Daniel J. Sussman, Timothy Bell, Frances Ginn Howard, Jonus Reyna
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Patent number: 9594072Abstract: A cytological analysis test for 3D cell classification from a specimen. The method includes isolating and preserving a cell from the specimen and enriching the cell before embedding the enriched cell into an optical medium. The embedded cell is injected into a capillary tube where pressure is applied until the cell appears in a field of view of a pseudo-projection viewing subsystem to acquire a pseudo-projection image. The capillary tube rotates about a tube axis to provide a set of pseudo-projection images for each embedded cell which are reconstructed to produce a set of 3D cell reconstructions. Reference cells are classified and enumerated and a second cell classifier detects target cells. An adequacy classifier compares the number of reference cells against a threshold value of enumerated reference cells to determine specimen adequacy.Type: GrantFiled: June 30, 2015Date of Patent: March 14, 2017Assignee: VISIONGATE, INC.Inventors: Michael G. Meyer, Rahul Katdare, Chris Presley, Timothy Bell
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Publication number: 20170003267Abstract: A cytological analysis test for 3D cell classification from a specimen. The method includes isolating and preserving a cell from the specimen and enriching the cell before embedding the enriched cell into an optical medium. The embedded cell is injected into a capillary tube where pressure is applied until the cell appears in a field of view of a pseudo-projection viewing subsystem to acquire a pseudo-projection image. The capillary tube rotates about a tube axis to provide a set of pseudo-projection images for each embedded cell which are reconstructed to produce a set of 3D cell reconstructions. Reference cells are classified and enumerated and a second cell classifier detects target cells. An adequacy classifier compares the number of reference cells against a threshold value of enumerated reference cells to determine specimen adequacy.Type: ApplicationFiled: June 30, 2015Publication date: January 5, 2017Applicant: VISIONGATE, INC.Inventors: Michael G. Meyer, Rahul Katdare, Chris Presley, Timothy Bell
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Patent number: 8136188Abstract: A combination pipe cutter and can lid opener comprising a means for cutting and a means for opening a can having a lid. The combination pipe cutter and can lid opener comprises two handles, one having a holder to hold a pipe and the other having a blade, wherein the blade is utilized to cut the pipe in the holder. The insides of the handles comprise semicircular openings having gripping teeth for opening the lid of a container. To open the lid of the container, the semicircular cutouts of the first handle and second handle are positioned around the perimeter of the lid, wherein the gripping teeth cooperatively engage the lid thereby opening the container by turning the combination pipe cutter and can lid opener.Type: GrantFiled: May 7, 2008Date of Patent: March 20, 2012Inventor: Timothy Bell
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Patent number: 7732797Abstract: A device and method for detecting the presence or absence of an object which has repetitive motion are disclosed comprising, a receiver for receiving a signal from the object, and circuitry for determining the presence or absence of the object to be detected, wherein the circuitry records the signal from the receiver as a pattern of data during at least part of the repetitive motion of the object, compares the data with a previously recorded data pattern and, produces an output signal based on the comparison. The signal may be received during discrete time intervals, and may be light which can be transmitted with varying intensity. The circuitry may determine the value of signal received at a receiver and produce a binary value. The signal received at the receiver can be reflected from the object to be detected.Type: GrantFiled: September 7, 2005Date of Patent: June 8, 2010Assignee: Renishaw PLCInventors: Victor Gordon Stimpson, Colin Timothy Bell, William Kenneth Davies, Paul Maxted
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Publication number: 20100021588Abstract: A grain-based food product is provided which is formed from a premix compacted granules having a narrow particle size distribution. The premix flows easily, does not clump, and reduces dust.Type: ApplicationFiled: September 29, 2009Publication date: January 28, 2010Applicants: PepsiCo, Inc., E.I.Du Pont De Nemours And CompanyInventors: Robert Chatel, Yongsoo Chung, Ann Marie Baker, Thomas S. Wolters, Timothy A. Bell, Steven W. Couch
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Publication number: 20090277310Abstract: A combination pipe cutter and can lid opener comprising a means for cutting and a means for opening a can having a lid. The combination pipe cutter and can lid opener comprises two handles, one having a holder to hold a pipe and the other having a blade, wherein the blade is utilized to cut the pipe in the holder. The insides of the handles comprise semicircular openings having gripping teeth for opening the lid of a container. To open the lid of the container, the semicircular cutouts of the first handle and second handle are positioned around the perimeter of the lid, wherein the gripping teeth cooperatively engage the lid thereby opening the container by turning the combination pipe cutter and can lid opener.Type: ApplicationFiled: May 7, 2008Publication date: November 12, 2009Inventor: Timothy Bell
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Publication number: 20090068314Abstract: A grain-based food product is provided which is formed from a premix compacted granules having a narrow particle size distribution. The premix flows easily, does not clump, and reduces dust.Type: ApplicationFiled: September 12, 2007Publication date: March 12, 2009Inventors: Robert Chatel, Yongsoo Chung, Ann Marie Baker, Thomas S. Wolters, Timothy A. Bell, Steven W. Couch
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Publication number: 20070040304Abstract: The invention provides a treated powder having improved loose bulk density comprising a silanized inorganic powder treated with a long chain fatty acid or salts thereof, wherein the amount of the long chain fatty acid is about 0.25% to about 2 wt %, based on the total weight of the treated powder.Type: ApplicationFiled: July 13, 2006Publication date: February 22, 2007Inventors: Timothy Bell, Joy Bloom
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Publication number: 20060278547Abstract: A package for an elongate surgical device, such as a catheter, includes an elongate tube formed into a coil configuration with a first coil portion disposed adjacent to a second coil portion. A thermal weld bonds the coil portions in a fixed relationship and with a strength sufficient to prevent peeling the first coil portion from the second coil portion. The surgical device can then be loaded into the tube, pouched and sterilized for ultimate distribution. In an associated method, the tube is coiled on a turntable and moved relative to heating stations where the thermal bonds can be formed.Type: ApplicationFiled: July 6, 2006Publication date: December 14, 2006Inventors: Howard Rowe, Timothy Bell, Larry Bonzomet, William Patton
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Publication number: 20060072997Abstract: The present invention is directed to a system and a method to unload bulk powders from large bulk containers. The system and method are particularly useful for unloading bulk cohesive powders.Type: ApplicationFiled: August 8, 2005Publication date: April 6, 2006Inventors: Timothy Bell, Peter Clark, John Connolly, Catherine Wilson, Andrew Mitchell, James Mothersbaugh
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Patent number: D693125Type: GrantFiled: September 24, 2012Date of Patent: November 12, 2013Inventor: Timothy A. Bell