Patents by Inventor Timothy Burn

Timothy Burn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DETECTION OF PATIENTS AT RISK FOR DEVELOPING INTEGRIN ANTAGONIST/ AGONIST MEDIATED DISEASE STATES
    Publication number: 20020081624
    Abstract: This invention relates to the detection of patients at risk for developing integrin antagonist/agonist mediated disease states. This invention relates to assays useful for the detection in a patient bodily fluid sample of drug-dependent antibodies which bind to integrins, or intergrin-associated proteins or complexes thereof in the presence of an integrin antagonist/agonist. This invention also relates to assays useful for the detection in a patient bodily fluid sample of drug-dependent antibodies (DDABS) that bind to integrins, including the platelet glycoprotein IIb/IIIa (GPIIb/IIIa), in the presence of a integrin agonist and/or antagonist. This invention also relates to procedures for identifying integrin antagonists/agonists that are less prone to elicit integrin antagonist/agonist mediated disease states.
    Type: Application
    Filed: January 26, 1999
    Publication date: June 27, 2002
    Inventors: JEFFREY T. BILLHEIMER, DIETMAR A. SEIFFERT, LEAH A. BRETH, TIMOTHY BURN, IRA B. DICKER, HENRY J. GEORGE, JEANNINE M. HOLLIS, GREGORY F. HOLLIS, JENNIFER E. KOCHIE, KARYN T. O'NEIL
  • Polycystic kidney disease gene and protein
    Patent number: 6071717
    Abstract: The present invention involves isolated nucleic acid encoding human PKD1, and sequences derived therefrom. The invention also encompasses vectors comprising these nucleic acids, host cells transformed with the vectors, and methods for producing PKD1 protein or fragments thereof. In another aspect, the invention involves isolated oligonucleotides that hybridize only to the authentic expressed PKD1 gene, and not to PKD1 homologues. In yet another aspect, the invention involves isolated mutant PKD1 genes, and their cDNA cognates. Further provided are isolated oligonucleotides that discriminate between normal and mutant versions of the PKD1 gene. Methods and compositions for treating APKD or disease conditions having the characteristics of APKD are also provided.
    Type: Grant
    Filed: June 4, 1996
    Date of Patent: June 6, 2000
    Assignees: Genzyme Corporation, Johns Hopkins University
    Inventors: Katherine Klinger, Timothy Burn, Timothy Connors, William Dackowski, Gregory Germino, Feng Qian, Gregory Landes
  • Human chromosome 16 genes, compositions, methods of making and using same
    Patent number: 6028173
    Abstract: This invention provides an isolated human netrin polypeptide. Netrins define a family of diffusable factors involved in axon outgrowth.
    Type: Grant
    Filed: June 17, 1996
    Date of Patent: February 22, 2000
    Assignee: Genzyme Corporation
    Inventors: Gregory Landes, Timothy Burn, Timothy Connors, William Dackowski, Terence Van Raay, Katherine Klinger