Patents by Inventor Timothy C. Barden

Timothy C. Barden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FAAH inhibitors
    Patent number: 9657012
    Abstract: The present disclosure relates to compounds useful as inhibitors of the enzyme Fatty Acid Amide Hydrolase (FAAH). The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the compositions in the treatment or prevention of various disorders. Compounds of the invention are described in Table 1.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: May 23, 2017
    Assignee: Ironwood Pharmaceuticals, Inc.
    Inventors: Colleen Hudson, Timothy C. Barden, James Jia, Ara Mermerian, Bo Peng, Jane Yang, Xiang Y. Yu, Kevin Sprott, Angelika Fretzen
  • FAAH Inhibitors
    Publication number: 20150175599
    Abstract: The present disclosure relates to compounds useful as inhibitors of the enzyme Fatty Acid Amide Hydrolase (FAAH). The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the compositions in the treatment or prevention of various disorders. Compounds of the invention are described in Table 1.
    Type: Application
    Filed: December 22, 2011
    Publication date: June 25, 2015
    Applicant: Ironwood Pharmaceuticals, Inc.
    Inventors: Colleen Hudson, Timothy C. Barden, James Jia, Ara Mermerian, Bo Peng, Jane Yang, Xiang Y. Yu, Kevin Sprott, Angelika Fretzen
  • ORGANOMETAL BENZENEPHOSPHONATE COUPLING AGENTS
    Publication number: 20090292135
    Abstract: The invention relates to chemical genera of organometal benzenephosphonates useful in cross-coupling organic synthesis, having general formula: where R is selected from boron, zinc, tin and silicon residues.
    Type: Application
    Filed: May 9, 2006
    Publication date: November 26, 2009
    Applicant: Ironwood Pharmaceuticals, Inc.
    Inventors: Timothy C. Barden, Peter Lee, Eduardo J. Martinez, Wayne C. Schairer, John J. Talley, JingJing Yang
  • BIPHENYLAZETIDINONE CHOLESTEROL ABSORPTION INHIBITORS
    Publication number: 20090131395
    Abstract: The invention relates to a chemical genus of 4-biphenyl-1-phenylazetidin-2-ones useful in the treatment of hypercholesterolemia and other disorders. The compounds have the general formula I: Pharmaceutical compositions and methods for treating cholesterol- and lipid-associated diseases are also disclosed.
    Type: Application
    Filed: May 5, 2006
    Publication date: May 21, 2009
    Applicant: MICROBIA, INC.
    Inventors: Stephen Antonelli, Regina Lundrigan, Eduardo J. Martinez, Wayne C. Schairer, John J. Talley, Timothy C. Barden, JingJing Yang, Daniel P. Zimmer
  • Processes for Production of 4-(Biphenylyl)Azetidin-2-One Phosphonic Acids
    Publication number: 20090099355
    Abstract: The present invention relates to processes for the production of 4-(biphenylyl)azetidin-2-one phosphonic acid derivatives of formula
    Type: Application
    Filed: May 25, 2006
    Publication date: April 16, 2009
    Applicant: MICROBIA, INC.
    Inventors: Stephen Antonelli, Timothy C. Barden, Peter Lee, Eduardo J. Martinez, Wayne C. Schairer, John J. Talley
  • Processes For Production of Phenolic 4-Biphenylylazetidin-2-Ones
    Publication number: 20080200669
    Abstract: The present invention relates to processes for the production of phenolic 4-biphenylylazetidin-2-one derivatives of formula
    Type: Application
    Filed: May 11, 2006
    Publication date: August 21, 2008
    Applicant: Microbia, Inc.
    Inventors: Timothy C. Barden, Peter Lee, Eduardo J. Martinez, Wayne C. Schairer, John J. Talley
  • 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONES
    Publication number: 20080167255
    Abstract: 4-Biarylyl-1-phenylazetidin-2-ones useful for the treatment of hypercholesterolemia are disclosed. The compounds are of the general formula in which represents an aryl or heteroaryl residue; Ar represents an aryl residue; U is a two to six atom chain; and the R's represent substituents.
    Type: Application
    Filed: December 11, 2007
    Publication date: July 10, 2008
    Applicant: MICROBIA, INC.
    Inventors: Eduardo J. Martinez, John J. Talley, Stephen Antonelli, Timothy C. Barden, Regina Lundrigan-Soucy, Wayne C. Schairer, Jing-Jing Yang, Daniel P. Zimmer, Brian Cali, Mark G. Currie, Peter S. Yorgey
  • 4-Biarylyl-1-phenylazetidin-2-ones
    Patent number: 7320972
    Abstract: 4-Biarylyl-1-phenylazetidin-2-ones useful for the treatment of hypercholesterolemia are disclosed. The compounds are of the general formula in which represents an aryl or heteroaryl residue; Ar represents an aryl residue; U is a two to six atom chain; and the R's represent substituents.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: January 22, 2008
    Assignee: Microbia, Inc.
    Inventors: Eduardo Martinez, John J. Talley, Stephen Antonelli, Timothy C. Barden, Regina Lundrigan-Soucy, Wayne C. Schairer, Jing-Jing Yang, Daniel P. Zimmer, Brian Cali, Mark G. Currie, Peter S. Yorgey
  • 9-[(substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines
    Patent number: 5371076
    Abstract: The invention provides compounds of the formula: ##STR1## wherein R, R.sup.1, R.sup.2 and W are defined in the specification. These compounds are useful as antibiotic agents.
    Type: Grant
    Filed: April 2, 1993
    Date of Patent: December 6, 1994
    Assignee: American Cyanamid Company
    Inventors: Ving J. Lee, Brian L. Buckwalter, Timothy C. Barden
  • 13-alkyl-23-imino derivative of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
    Patent number: 5055486
    Abstract: There are provided certain 13-alkyl-23-imino-LL-F28249 compounds which are useful for controlling endo- and ectoparasites, insects, acarids and nematodes.
    Type: Grant
    Filed: December 22, 1989
    Date of Patent: October 8, 1991
    Assignee: American Cyanamid Company
    Inventors: Timothy C. Barden, Brian L. Buckwalter