Patents by Inventor Timothy C. Doyle

Timothy C. Doyle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8372597
    Abstract: The present invention provides methods of introducing a polynucleotide into a target cell, wherein the method employs a light generating protein coding sequence acting as a reporter. An important advantage of the methods described herein is that drug resistant target cells or target cells having no useful auxotrophic markers can be effectively transformed. The present invention also includes transformed cells produced by the methods described herein. Also described are light generating protein coding sequence modifications, a variety of vectors, and methods of using the transformed cells of the present invention.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: February 12, 2013
    Assignee: Xenogen Corporation
    Inventors: Kevin P. Francis, Timothy C. Doyle, Kevin A. Nawotka
  • Publication number: 20080033782
    Abstract: A method and system for product measurement validation is provided. The method includes receiving a product sales file from a number of retail entities, the product sales file including records of universal product code (UPC) data and measured values of products. The method also includes grouping the records in each of the product sales files by product and supplier identifiers and determining a consistency value for each product. The consistency value is determined by comparing the measured value of the product to a validation value assigned to the product via the UPC, the validation value representing a target measurement for the product. The consistency value is further determined by graphing measurement values and identifying any deviance resulting from the comparing and analyzing results of the graphing by product identifier and supplier identifier to determine whether the measured values of a product provided by a supplier are consistent with the validation value.
    Type: Application
    Filed: August 1, 2006
    Publication date: February 7, 2008
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Robin J. Doyle, Timothy C. Doyle
  • Patent number: 7090994
    Abstract: The present invention provides methods of introducing a polynucleotide into a target cell, wherein the method employs a light generating protein coding sequence acting as a reporter. An important advantage of the methods described herein is that drug resistant target cells or target cells having no useful auxotrophic markers can be effectively transformed. The present invention also includes transformed cells produced by the methods described herein. Also described are light generating protein coding sequence modifications, a variety of vectors, and methods of using the transformed cells of the present invention.
    Type: Grant
    Filed: March 7, 2002
    Date of Patent: August 15, 2006
    Assignee: Xenogen Corporation
    Inventors: Kevin P. Francis, Timothy C. Doyle, Kevin A. Nawotka
  • Publication number: 20020192755
    Abstract: The present invention provides methods of introducing a polynucleotide into a target cell, wherein the method employs a light generating protein coding sequence acting as a reporter. An important advantage of the methods described herein is that drug resistant target cells or target cells having no useful auxotrophic markers can be effectively transformed. The present invention also includes transformed cells produced by the methods described herein. Also described are light generating protein coding sequence modifications, a variety of vectors, and methods of using the transformed cells of the present invention.
    Type: Application
    Filed: March 7, 2002
    Publication date: December 19, 2002
    Inventors: Kevin P. Francis, Timothy C. Doyle, Kevin A. Nawotka