Patents by Inventor Timothy C. Nichols

Timothy C. Nichols has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130012463
    Abstract: The present invention provides a novel method for inhibiting the cyclooxygenase enzyme COX-2. The method is comprised of administering a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 mediated diseases and conditions. The method for preventing and treating COX-2 mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: June 11, 2012
    Publication date: January 10, 2013
    Applicant: Unigen, Inc.
    Inventors: Qi Jia, Timothy C. Nichols, Eric E. Rhoden, Scott Waite
  • Publication number: 20120329863
    Abstract: The present disclosure provides compositions and methods for alleviating inflammatory-associated diseases and conditions. These methods include administering individual and/or a mixture of multiple flavans isolated from a single or multiple Acacia genus of plants. The present disclosure also includes methods for isolating and purifying from an Acacia genus of plants a composition of flavans having dual specificity for cyclooxygenase (COX-2) and 5-lipoxygenase (5-LO) enzymes.
    Type: Application
    Filed: January 20, 2012
    Publication date: December 27, 2012
    Applicant: Unigen, Inc.
    Inventors: Qi Jia, Timothy C. Nichols, Eric E. Rhoden, Scott Waite
  • Patent number: 8213857
    Abstract: Providing content to a device. Content stored on a device can be examined or searched based on the programming of channels that are available to the device over various networks. The content can be searched using other rules related to user preferences or content characteristics. Based on the results of the examination of the content, playlists are generated. Each playlist includes content from the device that matches or partially matches the content associated with one of the channels. Using the playlists, a user can load content from their device that has a theme consistent with a particular channel. When signal loss is detected for a given channel, the playlist associated with that channel can be loaded and played by the device. The device can resume playing the channel when the signal is again adequately detected.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: July 3, 2012
    Assignee: Dell Products L.P.
    Inventors: Timothy C. Nichols, Mark Andrew Ross, Clare Lawson, Arthur Anthonie van Hoff
  • Publication number: 20120128647
    Abstract: Fixed-dried blood cells carrying an active agent are described, along with methods of making the same, methods of using the same, and compositions containing the same. The blood cells are preferably blood platelets.
    Type: Application
    Filed: September 28, 2007
    Publication date: May 24, 2012
    Inventors: Timothy C. Nichols, Thomas Fischer, Marjorie S. Read
  • Publication number: 20120075664
    Abstract: The present disclosure is directed to systems and methods for configuring mobile communication devices to identify and communicate with wireless printing devices. These systems and methods may include determining available wireless printing devices, selecting a desired wireless printing device, attempting to establish communication between the mobile communication device and the wireless printing device using a first communication protocol, prompting a user to indicate the successfulness of the first communication protocol, and configuring the mobile communication device for printing to the wireless printing device using the first communication protocol if the first communication protocol successfully communicated with the wireless printing device.
    Type: Application
    Filed: December 6, 2010
    Publication date: March 29, 2012
    Applicant: Wellala, Inc.
    Inventors: Timothy C. Nichols, Geoffrey W. Chatterton, Ramaneek Khanna, Eric D. Bauswell, Anthony R. Chvala
  • Patent number: 8124134
    Abstract: The present invention provides a novel method for simultaneously inhibiting the cyclooxygenase COX-2 and 5-lipoxygenase (5-LO) enzymes. The method for the simultaneous dual inhibition of COX-2 and 5-LO is comprised of administering a composition containing an individual and/or a mixture of multiple flavans isolated from a single plant or multiple plants in the Acacia genus of plants to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 and 5-LO mediated diseases and conditions. The method for preventing and treating COX-2 and 5-LO mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition comprising an individual and/or a mixture of multiple flavans isolated from a single plant or multiple plants in the Acacia genus of plants and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: February 28, 2012
    Assignee: Unigen, Inc.
    Inventors: Qi Jia, Timothy C. Nichols, Eric Rhoden, Scott Waite
  • Publication number: 20110245333
    Abstract: The present invention provides a novel method for inhibiting the cyclooxygenase enzyme COX-2. The method is comprised of administering a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 mediated diseases and conditions. The method for preventing and treating COX-2 mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 11, 2011
    Publication date: October 6, 2011
    Applicant: Unigen, Inc.
    Inventors: Qi Jia, Timothy C. Nichols, Eric E. Rhoden, Scott Walte
  • Patent number: 7901674
    Abstract: Fixed-dried blood cells carrying an active agent are described, along with methods of making the same, methods of using the same, and compositions containing the sane. The blood cells may be red blood cells or blood platelets.
    Type: Grant
    Filed: May 21, 2007
    Date of Patent: March 8, 2011
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Timothy C. Nichols, Thomas Fischer, Marjorie S. Read
  • Patent number: 7886343
    Abstract: Authenticating a third party client system prior to providing Internet access via an Internet access point. In a distributed computing system including an Internet access point, an authentication service, and a third party client system, an authentication service receives an authorization request from a third party client system. The authorization request is initiated in response to a single action being performed by a user of the third party client system. The user is not required to manually submit any identification information. The authorization request includes a unique client identifier for identifying the third party client system. The method also includes verifying that the third party client system associated with the unique client identifier is authorized to access the Internet via the Internet access point. If the third party client system is authorized to access the Internet, Internet access is provided to the third party client system.
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: February 8, 2011
    Assignee: Dell Products L.P.
    Inventors: Timothy Sullivan, Timothy C. Nichols, Timothy Bucher, John S. Evans
  • Patent number: 7746895
    Abstract: Guided discovery of content in a device. A device such as a satellite radio can received multiple data streams at least over networks including a satellite network or other wireless networks. The device includes filters that are based on the history of the device, the advertising history of the device, or on lists obtained from other devices. The data streams available to the device are filtered using the filters to discover content in the data streams. Content, including metadata or a portion of the content itself, discovered by the results of the filters can be stored at the device. The device notifies the user of the discovered content. The filters guide the discovery of content that may be of interest to the user of the device.
    Type: Grant
    Filed: July 29, 2005
    Date of Patent: June 29, 2010
    Assignee: Dell Products L.P.
    Inventors: Timothy Bucher, Mark A. Ross, Timothy C. Nichols
  • Publication number: 20100056042
    Abstract: Providing content to a device. Content stored on a device can be examined or searched based on the programming of channels that are available to the device over various networks. The content can be searched using other rules related to user preferences or content characteristics. Based on the results of the examination of the content, playlists are generated. Each playlist includes content from the device that matches or partially matches the content associated with one of the channels. Using the playlists, a user can load content from their device that has a theme consistent with a particular channel. When signal loss is detected for a given channel, the playlist associated with that channel can be loaded and played by the device. The device can resume playing the channel when the signal is again adequately detected.
    Type: Application
    Filed: November 10, 2009
    Publication date: March 4, 2010
    Applicant: DELL PRODUCTS L.P.
    Inventors: Timothy C. Nichols, Mark Andrew Ross, Clare Lawson, Arthur Anthonie van Hoff
  • Patent number: 7653342
    Abstract: Providing content to a device. Content stored on a device can be examined or searched based on the programming of channels that are available to the device over various networks. The content can be searched using other rules related to user preferences or content characteristics. Based on the results of the examination of the content, playlists are generated. Each playlist includes content from the device that matches or partially matches the content associated with one of the channels. Using the playlists, a user can load content from their device that has a theme consistent with a particular channel. When signal loss is detected for a given channel, the playlist associated with that channel can be loaded and played by the device. The device can resume playing the channel when the signal is again adequately detected.
    Type: Grant
    Filed: February 16, 2006
    Date of Patent: January 26, 2010
    Assignee: Dell Products L.P.
    Inventors: Timothy C. Nichols, Mark Andrew Ross, Clare Lawson, Arthur Anthonie van Hoff
  • Patent number: 7427488
    Abstract: Isolated and purified platelet voltage dependent calcium channel (VDCC) ?1 subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids, and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to platelet VDCC ?1 subunit polypeptides, and methods of producing the same, are also disclosed. Platelet VDCC ?1 subunit polypeptides have biological activity in calcium transport. Thus, therapeutic and diagnostic methods involving this activity are also disclosed.
    Type: Grant
    Filed: December 2, 2003
    Date of Patent: September 23, 2008
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Timothy C. Nichols, Nadia Malouf, Elizabeth Merricks
  • Patent number: 7358039
    Abstract: Fixed-dried red blood cells (RBCs), and processes for preparing the same are disclosed. The red blood cells, upon reconstitution with distilled water or appropriate buffer: bind oxygen with native affinities, have partial deformability, present minimal thrombogenicity to platelets, and have oblated blood group antigens. The RBCs are preferably fixed by means of cross-linkers with aldehyde functions such as paraformaldehyde or glutaraldehyde either alone or in combination. Native oxygen kinetics are achieved by preparing the red blood cells with 1,6-diphosphofructose. Blood group antigens and chemical functions that render the lyophilized RBCs thrombogenic are occluded by chemically attaching polyoxyethylene glycol polymers to the surface membrane of the red blood cells. The cross-linked red blood cells are preferably died by lyophilization.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: April 15, 2008
    Assignees: University of North Carolina at Chapel Hill, East Carolina University
    Inventors: Thomas H. Fischer, Marjorie S. Read, Arthur P. Bode, Timothy C. Nichols
  • Patent number: 7294455
    Abstract: Fixed-dried blood cells carrying an active agent are described, along with methods of making the same, methods of using the same, and compositions containing the same. The blood cells may be red blood cells or blood platelets.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: November 13, 2007
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Timothy C. Nichols, Thomas Fischer, Marjorie S. Read
  • Patent number: 7192611
    Abstract: The present invention provides a novel method for inhibiting the cyclooxygenase enzyme COX-2. The method is comprised of administering a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 mediated diseases and conditions. The method for preventing and treating COX-2 mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: February 28, 2003
    Date of Patent: March 20, 2007
    Assignee: Unigen Pharmaceuticals, Inc.
    Inventors: Qi Jia, Timothy C. Nichols, Eric E. Rhoden, Scott Waite
  • Patent number: 7108868
    Abstract: The present invention provides a novel method for simultaneously inhibiting the cyclooxygenase COX-2 and 5-lipoxygenase (5-LO) enzymes. The method for the simultaneous dual inhibition of COX-2 and 5-LO is comprised of administering a composition containing an individual and/or a mixture of multiple flavans isolated from a single plant or multiple plants in the Acacia genus of plants to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 and 5-LO mediated diseases and conditions. The method for preventing and treating COX-2 and 5-LO mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition comprising an individual and/or a mixture of multiple flavans isolated from a single plant or multiple plants in the Acacia genus of plants and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 22, 2002
    Date of Patent: September 19, 2006
    Assignee: Unigen Pharmaceuticals, Inc.
    Inventors: Qi Jia, Timothy C. Nichols, Eric Rhoden, Scott Waite
  • Patent number: 7041475
    Abstract: Isolated and purified platelet voltage dependent calcium channel (VDCC) ?1 subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to platelet VDCC ?1 subunit polypeptides, and methods of producing the same, are also disclosed. Platelet VDCC ?1 subunit polypeptides have biological activity in calcium transport. Thus, therapeutic and diagnostic methods involving this activity are also disclosed.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: May 9, 2006
    Assignee: University of North Carolina at Chapel Hill
    Inventors: Nadia Malouf, Timothy C. Nichols
  • Patent number: 6884573
    Abstract: Fixed-dried red blood cells (RBCs), and processes for preparing the same are disclosed. The red blood cells, upon reconstitution with distilled water or appropriate buffer: bind oxygen with native affinities, have partial deformability, present minimal thrombogenicity to platelets, and have oblated blood group antigens. The RBCs are preferably fixed by means of cross-linkers with aldehyde functions such as paraformaldehyde or glutaraldehyde either alone or in combination. Native oxygen kinetics are achieved by preparing the red blood cells with 1,6-diphosphofructose. Blood group antigens and chemical functions that render the lyophilized RBCs thrombogenic are occluded by chemically attaching polyoxyethylene glycol polymers to the surface membrane of the red blood cells. The cross-linked red blood cells are preferably died by lyophilization.
    Type: Grant
    Filed: August 30, 2002
    Date of Patent: April 26, 2005
    Assignees: The University of North Carolina at Chapel Hill, East Carolina University
    Inventors: Thomas H. Fischer, Marjorie S. Read, Arthur P. Bode, Timothy C. Nichols
  • Publication number: 20040146851
    Abstract: Isolated and purified platelet voltage dependent calcium channel (VDCC) &agr;1 subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids, and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to platelet VDCC &agr;1 subunit polypeptides, and methods of producing the same, are also disclosed. Platelet VDCC &agr;1 subunit polypeptides have biological activity in calcium transport. Thus, therapeutic and diagnostic methods involving this activity are also disclosed.
    Type: Application
    Filed: December 2, 2003
    Publication date: July 29, 2004
    Inventors: Timothy C. Nichols, Nadia Malouf, ELizabeth Merricks