Patents by Inventor Timothy C. Nichols
Timothy C. Nichols has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130012463Abstract: The present invention provides a novel method for inhibiting the cyclooxygenase enzyme COX-2. The method is comprised of administering a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 mediated diseases and conditions. The method for preventing and treating COX-2 mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids and a pharmaceutically acceptable carrier.Type: ApplicationFiled: June 11, 2012Publication date: January 10, 2013Applicant: Unigen, Inc.Inventors: Qi Jia, Timothy C. Nichols, Eric E. Rhoden, Scott Waite
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Publication number: 20120329863Abstract: The present disclosure provides compositions and methods for alleviating inflammatory-associated diseases and conditions. These methods include administering individual and/or a mixture of multiple flavans isolated from a single or multiple Acacia genus of plants. The present disclosure also includes methods for isolating and purifying from an Acacia genus of plants a composition of flavans having dual specificity for cyclooxygenase (COX-2) and 5-lipoxygenase (5-LO) enzymes.Type: ApplicationFiled: January 20, 2012Publication date: December 27, 2012Applicant: Unigen, Inc.Inventors: Qi Jia, Timothy C. Nichols, Eric E. Rhoden, Scott Waite
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Patent number: 8213857Abstract: Providing content to a device. Content stored on a device can be examined or searched based on the programming of channels that are available to the device over various networks. The content can be searched using other rules related to user preferences or content characteristics. Based on the results of the examination of the content, playlists are generated. Each playlist includes content from the device that matches or partially matches the content associated with one of the channels. Using the playlists, a user can load content from their device that has a theme consistent with a particular channel. When signal loss is detected for a given channel, the playlist associated with that channel can be loaded and played by the device. The device can resume playing the channel when the signal is again adequately detected.Type: GrantFiled: November 10, 2009Date of Patent: July 3, 2012Assignee: Dell Products L.P.Inventors: Timothy C. Nichols, Mark Andrew Ross, Clare Lawson, Arthur Anthonie van Hoff
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Publication number: 20120128647Abstract: Fixed-dried blood cells carrying an active agent are described, along with methods of making the same, methods of using the same, and compositions containing the same. The blood cells are preferably blood platelets.Type: ApplicationFiled: September 28, 2007Publication date: May 24, 2012Inventors: Timothy C. Nichols, Thomas Fischer, Marjorie S. Read
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Publication number: 20120075664Abstract: The present disclosure is directed to systems and methods for configuring mobile communication devices to identify and communicate with wireless printing devices. These systems and methods may include determining available wireless printing devices, selecting a desired wireless printing device, attempting to establish communication between the mobile communication device and the wireless printing device using a first communication protocol, prompting a user to indicate the successfulness of the first communication protocol, and configuring the mobile communication device for printing to the wireless printing device using the first communication protocol if the first communication protocol successfully communicated with the wireless printing device.Type: ApplicationFiled: December 6, 2010Publication date: March 29, 2012Applicant: Wellala, Inc.Inventors: Timothy C. Nichols, Geoffrey W. Chatterton, Ramaneek Khanna, Eric D. Bauswell, Anthony R. Chvala
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Patent number: 8124134Abstract: The present invention provides a novel method for simultaneously inhibiting the cyclooxygenase COX-2 and 5-lipoxygenase (5-LO) enzymes. The method for the simultaneous dual inhibition of COX-2 and 5-LO is comprised of administering a composition containing an individual and/or a mixture of multiple flavans isolated from a single plant or multiple plants in the Acacia genus of plants to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 and 5-LO mediated diseases and conditions. The method for preventing and treating COX-2 and 5-LO mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition comprising an individual and/or a mixture of multiple flavans isolated from a single plant or multiple plants in the Acacia genus of plants and a pharmaceutically acceptable carrier.Type: GrantFiled: July 13, 2006Date of Patent: February 28, 2012Assignee: Unigen, Inc.Inventors: Qi Jia, Timothy C. Nichols, Eric Rhoden, Scott Waite
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Publication number: 20110245333Abstract: The present invention provides a novel method for inhibiting the cyclooxygenase enzyme COX-2. The method is comprised of administering a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 mediated diseases and conditions. The method for preventing and treating COX-2 mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids and a pharmaceutically acceptable carrier.Type: ApplicationFiled: April 11, 2011Publication date: October 6, 2011Applicant: Unigen, Inc.Inventors: Qi Jia, Timothy C. Nichols, Eric E. Rhoden, Scott Walte
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Patent number: 7901674Abstract: Fixed-dried blood cells carrying an active agent are described, along with methods of making the same, methods of using the same, and compositions containing the sane. The blood cells may be red blood cells or blood platelets.Type: GrantFiled: May 21, 2007Date of Patent: March 8, 2011Assignee: The University of North Carolina at Chapel HillInventors: Timothy C. Nichols, Thomas Fischer, Marjorie S. Read
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Patent number: 7886343Abstract: Authenticating a third party client system prior to providing Internet access via an Internet access point. In a distributed computing system including an Internet access point, an authentication service, and a third party client system, an authentication service receives an authorization request from a third party client system. The authorization request is initiated in response to a single action being performed by a user of the third party client system. The user is not required to manually submit any identification information. The authorization request includes a unique client identifier for identifying the third party client system. The method also includes verifying that the third party client system associated with the unique client identifier is authorized to access the Internet via the Internet access point. If the third party client system is authorized to access the Internet, Internet access is provided to the third party client system.Type: GrantFiled: April 6, 2007Date of Patent: February 8, 2011Assignee: Dell Products L.P.Inventors: Timothy Sullivan, Timothy C. Nichols, Timothy Bucher, John S. Evans
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Patent number: 7746895Abstract: Guided discovery of content in a device. A device such as a satellite radio can received multiple data streams at least over networks including a satellite network or other wireless networks. The device includes filters that are based on the history of the device, the advertising history of the device, or on lists obtained from other devices. The data streams available to the device are filtered using the filters to discover content in the data streams. Content, including metadata or a portion of the content itself, discovered by the results of the filters can be stored at the device. The device notifies the user of the discovered content. The filters guide the discovery of content that may be of interest to the user of the device.Type: GrantFiled: July 29, 2005Date of Patent: June 29, 2010Assignee: Dell Products L.P.Inventors: Timothy Bucher, Mark A. Ross, Timothy C. Nichols
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Publication number: 20100056042Abstract: Providing content to a device. Content stored on a device can be examined or searched based on the programming of channels that are available to the device over various networks. The content can be searched using other rules related to user preferences or content characteristics. Based on the results of the examination of the content, playlists are generated. Each playlist includes content from the device that matches or partially matches the content associated with one of the channels. Using the playlists, a user can load content from their device that has a theme consistent with a particular channel. When signal loss is detected for a given channel, the playlist associated with that channel can be loaded and played by the device. The device can resume playing the channel when the signal is again adequately detected.Type: ApplicationFiled: November 10, 2009Publication date: March 4, 2010Applicant: DELL PRODUCTS L.P.Inventors: Timothy C. Nichols, Mark Andrew Ross, Clare Lawson, Arthur Anthonie van Hoff
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Patent number: 7653342Abstract: Providing content to a device. Content stored on a device can be examined or searched based on the programming of channels that are available to the device over various networks. The content can be searched using other rules related to user preferences or content characteristics. Based on the results of the examination of the content, playlists are generated. Each playlist includes content from the device that matches or partially matches the content associated with one of the channels. Using the playlists, a user can load content from their device that has a theme consistent with a particular channel. When signal loss is detected for a given channel, the playlist associated with that channel can be loaded and played by the device. The device can resume playing the channel when the signal is again adequately detected.Type: GrantFiled: February 16, 2006Date of Patent: January 26, 2010Assignee: Dell Products L.P.Inventors: Timothy C. Nichols, Mark Andrew Ross, Clare Lawson, Arthur Anthonie van Hoff
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Patent number: 7427488Abstract: Isolated and purified platelet voltage dependent calcium channel (VDCC) ?1 subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids, and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to platelet VDCC ?1 subunit polypeptides, and methods of producing the same, are also disclosed. Platelet VDCC ?1 subunit polypeptides have biological activity in calcium transport. Thus, therapeutic and diagnostic methods involving this activity are also disclosed.Type: GrantFiled: December 2, 2003Date of Patent: September 23, 2008Assignee: The University of North Carolina at Chapel HillInventors: Timothy C. Nichols, Nadia Malouf, Elizabeth Merricks
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Patent number: 7358039Abstract: Fixed-dried red blood cells (RBCs), and processes for preparing the same are disclosed. The red blood cells, upon reconstitution with distilled water or appropriate buffer: bind oxygen with native affinities, have partial deformability, present minimal thrombogenicity to platelets, and have oblated blood group antigens. The RBCs are preferably fixed by means of cross-linkers with aldehyde functions such as paraformaldehyde or glutaraldehyde either alone or in combination. Native oxygen kinetics are achieved by preparing the red blood cells with 1,6-diphosphofructose. Blood group antigens and chemical functions that render the lyophilized RBCs thrombogenic are occluded by chemically attaching polyoxyethylene glycol polymers to the surface membrane of the red blood cells. The cross-linked red blood cells are preferably died by lyophilization.Type: GrantFiled: January 24, 2005Date of Patent: April 15, 2008Assignees: University of North Carolina at Chapel Hill, East Carolina UniversityInventors: Thomas H. Fischer, Marjorie S. Read, Arthur P. Bode, Timothy C. Nichols
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Patent number: 7294455Abstract: Fixed-dried blood cells carrying an active agent are described, along with methods of making the same, methods of using the same, and compositions containing the same. The blood cells may be red blood cells or blood platelets.Type: GrantFiled: May 13, 2004Date of Patent: November 13, 2007Assignee: The University of North Carolina at Chapel HillInventors: Timothy C. Nichols, Thomas Fischer, Marjorie S. Read
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Patent number: 7192611Abstract: The present invention provides a novel method for inhibiting the cyclooxygenase enzyme COX-2. The method is comprised of administering a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 mediated diseases and conditions. The method for preventing and treating COX-2 mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids and a pharmaceutically acceptable carrier.Type: GrantFiled: February 28, 2003Date of Patent: March 20, 2007Assignee: Unigen Pharmaceuticals, Inc.Inventors: Qi Jia, Timothy C. Nichols, Eric E. Rhoden, Scott Waite
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Patent number: 7108868Abstract: The present invention provides a novel method for simultaneously inhibiting the cyclooxygenase COX-2 and 5-lipoxygenase (5-LO) enzymes. The method for the simultaneous dual inhibition of COX-2 and 5-LO is comprised of administering a composition containing an individual and/or a mixture of multiple flavans isolated from a single plant or multiple plants in the Acacia genus of plants to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 and 5-LO mediated diseases and conditions. The method for preventing and treating COX-2 and 5-LO mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition comprising an individual and/or a mixture of multiple flavans isolated from a single plant or multiple plants in the Acacia genus of plants and a pharmaceutically acceptable carrier.Type: GrantFiled: March 22, 2002Date of Patent: September 19, 2006Assignee: Unigen Pharmaceuticals, Inc.Inventors: Qi Jia, Timothy C. Nichols, Eric Rhoden, Scott Waite
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Patent number: 7041475Abstract: Isolated and purified platelet voltage dependent calcium channel (VDCC) ?1 subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to platelet VDCC ?1 subunit polypeptides, and methods of producing the same, are also disclosed. Platelet VDCC ?1 subunit polypeptides have biological activity in calcium transport. Thus, therapeutic and diagnostic methods involving this activity are also disclosed.Type: GrantFiled: December 20, 2001Date of Patent: May 9, 2006Assignee: University of North Carolina at Chapel HillInventors: Nadia Malouf, Timothy C. Nichols
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Patent number: 6884573Abstract: Fixed-dried red blood cells (RBCs), and processes for preparing the same are disclosed. The red blood cells, upon reconstitution with distilled water or appropriate buffer: bind oxygen with native affinities, have partial deformability, present minimal thrombogenicity to platelets, and have oblated blood group antigens. The RBCs are preferably fixed by means of cross-linkers with aldehyde functions such as paraformaldehyde or glutaraldehyde either alone or in combination. Native oxygen kinetics are achieved by preparing the red blood cells with 1,6-diphosphofructose. Blood group antigens and chemical functions that render the lyophilized RBCs thrombogenic are occluded by chemically attaching polyoxyethylene glycol polymers to the surface membrane of the red blood cells. The cross-linked red blood cells are preferably died by lyophilization.Type: GrantFiled: August 30, 2002Date of Patent: April 26, 2005Assignees: The University of North Carolina at Chapel Hill, East Carolina UniversityInventors: Thomas H. Fischer, Marjorie S. Read, Arthur P. Bode, Timothy C. Nichols
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Publication number: 20040146851Abstract: Isolated and purified platelet voltage dependent calcium channel (VDCC) &agr;1 subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids, and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to platelet VDCC &agr;1 subunit polypeptides, and methods of producing the same, are also disclosed. Platelet VDCC &agr;1 subunit polypeptides have biological activity in calcium transport. Thus, therapeutic and diagnostic methods involving this activity are also disclosed.Type: ApplicationFiled: December 2, 2003Publication date: July 29, 2004Inventors: Timothy C. Nichols, Nadia Malouf, ELizabeth Merricks