Patents by Inventor Timothy Constandinou

Timothy Constandinou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230404423
    Abstract: Apparatus for discriminating between tumour tissue and non-tumorous tissue in real-time, the apparatus comprising: a handheld bioimpedance probe having an elongate body and at least four stimulator electrodes mounted on a distal end of the elongate body, the electrodes being arranged to be held against a region of tissue in use; a current source configured to generate a stimulation current; a voltage sensor; a multiplexer coupled between the current source, the voltage sensor and the stimulator electrodes and configured to changeably switch between a plurality of switching configurations, wherein, in each switching configuration, a first two of the electrodes are connected to the current source, and a second two of the electrodes are connected to the voltage sensor, the electrodes that constitute the first two electrodes and the electrodes that constitute the second two electrodes changing from one switching configuration to the next; and processor-controlled circuitry configured to: control the switching con
    Type: Application
    Filed: October 13, 2020
    Publication date: December 21, 2023
    Inventors: Timothy CONSTANDINOU, Jinendra EKANAYAKE, Yan LIU, Steven WONG
  • Publication number: 20230277192
    Abstract: An actuator handle for a hand-held surgical tool, the actuator handle comprising: a body part adapted to be gripped by a user's hand, the body part having an end effector mounted or mountable thereon; an actuating member alongside the body part and arranged to be operably moveable by a single finger of the said hand, in a substantially linear manner between first and second positions relative to the body part, for actuating the end effector in use; and one or more coupling components coupled to the actuating member, for mechanically transmitting motive force from the actuating member to the end effector upon movement of the actuating member between the first and second positions by the user in use.
    Type: Application
    Filed: July 19, 2021
    Publication date: September 7, 2023
    Inventors: Timothy CONSTANDINOU, Jinendra EKANAYAKE, Matthew L. CAVUTO
  • Publication number: 20230165499
    Abstract: A neural interface arrangement comprising: a plurality of probes for subdural implantation into or onto a human brain, each probe including at least one sensing electrode, a coil for receiving power via inductive coupling, signal processing circuitry coupled to the sensing electrode(s), and means for wirelessly transmitting data-carrying signals arising from the sensing electrode(s); an array of coils for implantation above the dura, beneath the skull, the array of coils being for inductively coupling with the coil of each of the plurality of probes, for transmitting power to the probes; and a primary (e.g.
    Type: Application
    Filed: January 26, 2023
    Publication date: June 1, 2023
    Applicant: Imperial College Innovations Limited
    Inventors: Timothy CONSTANDINOU, Andrew JACKSON
  • Patent number: 11589790
    Abstract: A neural interface arrangement has multiple probes for subdural implantation into or onto a human brain. Each probe has at least one sensing electrode, a coil for receiving power via inductive coupling, signal processing circuitry coupled to the electrode(s), and a transmitter for wirelessly transmitting data signals arising from the electrode(s). An array of coils is implanted above the dura beneath the skull, for inductively coupling with the coil of each probe, and for transmitting power to the probes. A primary coil is connected to the coil array, for inductively coupling with an external transmitter device, and for receiving power from the external transmitter device. In use, the primary coil is operable to receive power from the external transmitter device by inductive coupling and to cause the coil array to transmit power to the probes by inductive coupling, and the probes wirelessly transmit data signals arising from the electrodes.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: February 28, 2023
    Assignee: IMPERIAL COLLEGE INNOVATIONS LIMITED
    Inventors: Timothy Constandinou, Andrew Jackson
  • Publication number: 20210338127
    Abstract: A probe assembly comprising: an electrode-based probe comprising a probe head and one or more slender electrodes extending from the probe head for insertion into biological tissue; and a support element disposed around one or more of said electrodes, distal from the probe head, the support element comprising one or more apertures through which said one or more electrodes pass, the probe head and said electrode(s) being movable relative to the support element during insertion; wherein the support element is configured to constrain the angle of the end of the said electrode(s) at the point of insertion into the tissue.
    Type: Application
    Filed: October 30, 2019
    Publication date: November 4, 2021
    Inventors: Matthew L. CAVUTO, Timothy CONSTANDINOU, Amos G. WINTER
  • Publication number: 20210059547
    Abstract: A neural interface arrangement comprising: a plurality of probes for subdural implantation into or onto a human brain, each probe including at least one sensing electrode, a coil for receiving power via inductive coupling, signal processing circuitry coupled to the sensing electrode(s), and a means for wirelessly transmitting data-carrying signals arising from the electrode(s); an array of coils is implanted for implantation above the dura, beneath the skull, the array of coils being for inductively coupling with the coil of each of the plurality of probes, for transmitting power to the probes; and a primary (e.g.
    Type: Application
    Filed: May 19, 2017
    Publication date: March 4, 2021
    Inventors: Timothy CONSTANDINOU, Andrew JACKSON
  • Publication number: 20200315477
    Abstract: A neural interface arrangement has multiple probes for subdural implantation into or onto a human brain. Each probe has at least one sensing electrode, a coil for receiving power via inductive coupling, signal processing circuitry coupled to the electrode(s), and a transmitter for wirelessly transmitting data signals arising from the electrode(s). An array of coils is implanted above the dura beneath the skull, for inductively coupling with the coil of each probe, and for transmitting power to the probes. A primary coil is connected to the coil array, for inductively coupling with an external transmitter device, and for receiving power from the external transmitter device. In use, the primary coil is operable to receive power from the external transmitter device by inductive coupling and to cause the coil array to transmit power to the probes by inductive coupling, and the probes wirelessly transmit data signals arising from the electrodes.
    Type: Application
    Filed: May 19, 2017
    Publication date: October 8, 2020
    Inventors: Timothy CONSTANDINOU, Andrew JACKSON
  • Publication number: 20200057875
    Abstract: A method by which a hub unit can discover IDs from a plurality of satellite units across a shared communication link that connects each of the satellite units to the hub unit, each satellite unit having a satellite unit ID, the method comprising the hub unit broadcasting a message over the shared communication link, the message including an ID segment with a string of bits shorter than a bit length of the satellite unit IDs and an ID segment location; and each satellite unit receiving the broadcast message and comparing the ID segment with an ID portion of its own satellite unit ID starting at the ID segment location, if the ID portion for a satellite unit matches the ID segment, the satellite unit transmitting its complete satellite unit ID to the hub unit over the shared communication link.
    Type: Application
    Filed: February 15, 2018
    Publication date: February 20, 2020
    Applicant: University of Newcastle Upon Tyne
    Inventors: Timothy Constandinou, Sara Ghoreishizadeh
  • Publication number: 20130077965
    Abstract: A method of optically outputting information (e.g. digital data) from a semiconductor device, the method comprising: providing a semiconductor device having a semiconducting p-n junction, the p-n junction having a region of reduced free charge carrier density; applying an electrical signal to modulate the extent of the said region, the electrical signal being representative of the information to be outputted; arranging incident light to pass through at least part of the said region, such that the light is at least partially absorbed in dependence upon the modulated extent of the said region, thereby producing intensity-modulated output light; and detecting the intensity of the output light and thereby determining the outputted information. Also provided is an electro-optical assembly, a package module for mounting a semiconductor device on a printed circuit board, and an integrated circuit chip.
    Type: Application
    Filed: February 1, 2011
    Publication date: March 28, 2013
    Applicant: IMPERIAL INNOVATIONS LIMITED
    Inventors: Konstantin Nikolic, Timothy Constandinou, Christofer Toumazou