Abstract: The present invention relates to systems, compositions, and methods for using bone mineral density ratios as a predictor of osteoarthritis. In particular, the present invention relates to comparing ratios of bone mineral density involving bones that are periarticular to determine a risk assessment for features of osteoarthritis.

Abstract: A system, method and computer program product for predicting osteoarthritis pain based on changes in barometric pressure and ambient temperature, including inputting average temperature and barometric pressure values; calculating based on the input average temperature and barometric pressure values a pain difference value; interpreting the calculated pain difference value to determine one of a plurality of increasing pain or decreasing pain values; and displaying the determined one of the plurality of the increasing pain or decreasing pain values.

Abstract: The invention encompasses a method of conducting a clinical trial of a test substance from a primary site, via the internet. The internet is used in various phases of a clinical trial, including: recruiting and screening for candidates who are eligible to participate in a clinical trial of a test substance using the internet; obtaining, directly from a participant at a remote site, personal information as well as information allowing a determination of any effect(s) of the test substance on the participant after use (e.g., by evaluation forms completed and transmitted over the internet); compiling data from multiple participants.