Patents by Inventor Timothy E. Weaver

Timothy E. Weaver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8124588
    Abstract: The present invention relates to recombinant chimeric proteins comprising a surfactant protein precursor N-terminally fused to a plasminogen activator or comprising a mature surfactant protein N-terminally or C-terminally fused to a plasminogen activator. The invention is also directed to the corresponding nucleic acid molecules encoding such fusion proteins as well as to a method for their production. The invention further refers to a pharmaceutical composition comprising such a fusion protein and to pharmacological uses of an inventive fusion protein for the prevention and/or treatment of inflammatory and interstitial lung diseases.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: February 28, 2012
    Assignee: Justus Liebig Universität Giessen
    Inventors: Werner Seeger, Andreas Günther, Clemens Ruppert, Philipp Markart, Viktor Magdolen, Timothy E. Weaver
  • Publication number: 20090305961
    Abstract: The present invention relates to recombinant chimeric proteins comprising a surfactant protein precursor N-terminally fused to a plasminogen activator or comprising a mature surfactant protein N-terminally or C-terminally fused to a plasminogen activator. The invention is also directed to the corresponding nucleic acid molecules encoding such fusion proteins as well as to a method for their production. The invention further refers to a pharmaceutical composition comprising such a fusion protein and to pharmacological uses of an inventive fusion protein for the prevention and/or treatment of inflammatory and interstitial lung diseases.
    Type: Application
    Filed: December 18, 2003
    Publication date: December 10, 2009
    Inventors: Werner Seeger, Andreas Günther, Clemens Ruppert, Philipp Markart, Viktor Magdolen, Timothy E. Weaver
  • Patent number: 6031075
    Abstract: Mature alveolar surfactant protein B and a process for producing the same is disclosed. The process includes the use of a fusion protein of SP-B having a propeptide only at its amino terminus. A propeptide at its carboxyl terminus is not necessary, and thus not included in the fusion protein, to produce the mature SP-B of this process. Cleavage of the amino-terminus propeptide results in the production of mature SP-B.
    Type: Grant
    Filed: February 5, 1996
    Date of Patent: February 29, 2000
    Assignee: Children's Hospital Medical Center
    Inventor: Timothy E. Weaver