Patents by Inventor Timothy Edward Adams

Timothy Edward Adams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Structure of the insulin receptor ectodomain
    Patent number: 8301398
    Abstract: The present invention relates to the crystal structure of the insulin receptor ectodomain, to the nature of its N-linked glycans and to methods of using the crystal and related structural information to screen for and design compounds that interact with or modulate the insulin receptor and/or the closely-related insulin-like growth factor receptors or variants thereof.
    Type: Grant
    Filed: June 22, 2007
    Date of Patent: October 30, 2012
    Assignee: Walter and Eliza Hall Institute of Medical Research
    Inventors: Thomas P. J. Garrett, Timothy Edward Adams, George Lovrecz, Neil Moreton McKern, Michael Colin Lawrence, Lindsay Gale Sparrow, Colin Wesley Ward, Meizhen Lou, Victor Strelstov
  • Truncated EGF Receptor
    Publication number: 20090117134
    Abstract: The present invention relates to truncated EGF receptor molecules that exhibit increased binding affinities for EGFR ligands such as EGF and TGF1. The present invention also relates to methods of screening for EGF receptor ligands and methods of treatment which involve the use of these molecules.
    Type: Application
    Filed: October 20, 2008
    Publication date: May 7, 2009
    Applicants: Commonwealth Scientific and Industrial Research Organisation, Ludwig institute for Cancer Research
    Inventors: Colin Wesley WARD, Neil Moreton McKern, George Oscar Lovrecz, Robert Nicholas Jorissen, Thomas Peter John Garrett, Thomas Charles Elleman, Anthony Wilkes Burgess, Timothy Edward Adams, Teresa Anne Domagala, Edouard Nice
  • Truncated EGF receptor
    Patent number: 7449559
    Abstract: The present invention relates to truncated EGF receptor molecules that exhibit increased binding affinities for EGFR ligands such as EGF and TGF1. The present invention also relates to methods of screening for EGF receptor ligands and methods of treatment which involve the use of these molecules.
    Type: Grant
    Filed: August 22, 2005
    Date of Patent: November 11, 2008
    Assignees: Commonwealth Scientific and Industrial Research Organisation, Ludwig Insitutute for Cancer Research
    Inventors: Colin Wesley Ward, Neil Moreton McKern, George Oscar Lovrecz, Robert Nicholas Jorissen, Thomas Peter John Garrett, Thomas Charles Elleman, Antony Wilkes Burgess, Timothy Edward Adams, Teresa Anne Domagala, Edouard Collins Nice
  • Truncated EGF receptor
    Patent number: 6946543
    Abstract: The present invention relates to truncated EGF receptor molecules that exhibit increased binding affinities for EGFR ligands such as EGF and TGF-?. The present invention also relates to methods of screening for EGF receptor ligands and methods of treatment which involve the use of these molecules.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: September 20, 2005
    Assignees: Commonwealth Scientific and Industrial Research Organisation, Ludwig Institute for Cancer Research
    Inventors: Colin Wesley Ward, Neil Morton McKern, George Oscar Lovrecz, Robert Nicholas Jorissen, Thomas Peter John Garrett, Thomas Charles Elleman, Antony Wilkes Burgess, Timothy Edward Adams, Teresa Anne Domagala, Edouard Nice
  • Methods of screening based on the egf receptor crystal structure
    Publication number: 20040248196
    Abstract: This invention relates to the structure of members of the epidermal growth factor (EGF) receptor family and to receptor/ligand interactions. In particular, it relates to the field of using the EGF receptor family structure to select and screen for compounds that inhibit the formation of active receptor dimers.
    Type: Application
    Filed: July 14, 2004
    Publication date: December 9, 2004
    Inventors: Timothy Edward Adams, Antony Wilks Burgess, Thomas Charles Elleman, Thomas Peter John Garrett, Robert Nicholas Jorissen, Meizhen Lou, George Oscar Lovrecz, Neil Moreton Mckern, Edouard Collins Nice, Colin Wesley Ward
  • Truncated egf receptor
    Publication number: 20030108953
    Abstract: The present invention relates to truncated EGF receptor molecules that exhibit increased binding affinities for EGFR ligands such as EGF and TNFI. The present invention also relates to methods of screening for EGF receptor ligands and methods of treatment which involve the use of these molecules.
    Type: Application
    Filed: October 10, 2002
    Publication date: June 12, 2003
    Inventors: Colin Wesley Ward, Neil Moreton McKern, George Oscar Lovrecz, Robert Nicholas Jorissen, Thomas Peter John Garrett, Thomas Charles Elleman, Anthony Wilkes Burgess, Timothy Edward Adams, Teresa Anne Domagala, Edouard Nice