Patents by Inventor Timothy G. Helentjaris

Timothy G. Helentjaris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6713666
    Abstract: Methods and compositions for increasing yield in plants, particularly seed plants, are provided. The compositions comprise novel nucleic acid molecules encoding invertase inhibitors, antisense nucleotides corresponding to invertase inhibitors, and variants and fragments thereof. Such compositions find use in methods to modulate invertase activity in plants. The compositions are also useful in methods to modulate kernel development and for protecting plants against the harmful/detrimental effects of stress and adverse environmental conditions. The nucleotide sequences may be provided in constructs for temporal, developmental, and tissue preference. Transformed plants, plant cells, tissues, and seeds are additionally provided.
    Type: Grant
    Filed: February 9, 2001
    Date of Patent: March 30, 2004
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Timothy G. Helentjaris, Nicholas J. Bate, Stephen M. Allen
  • Patent number: 6677502
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase protein. The invention also relates to the construction of a chimeric gene encoding all or a substantial portion of the protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the protein in a transformed host cell.
    Type: Grant
    Filed: July 12, 2000
    Date of Patent: January 13, 2004
    Assignees: E.I. du Pont de Nemours and Company, Pioneer Hi-Bred International
    Inventors: Stephen M. Allen, Anthony J. Kinney, J. Antoni Rafalski, Emil M. Orozco, Jr., Guo-Hua Miao, Omolayo O. Famodu, Jian-Ming Lee, Karin N. Lohman, Alan R. Rendina, Hajime Sakai, Zude Weng, Perry G. Caimi, Yiwen Fang, Jennie Bih-Jien Shen, Ilham L. Zoughi, Shawn L. Anderson, Jinrui Shi, Guihua Lu, Timothy G. Helentjaris, Chun Ping Li
  • Publication number: 20030221224
    Abstract: The invention provides methods for enhancing maize silk exsertion under stress conditions and compositions relating to such methods, including nucleic acids and proteins. The invention further provides recombinant expression cassettes, host cells, and transgenic plants.
    Type: Application
    Filed: April 8, 2003
    Publication date: November 27, 2003
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Christopher Zinselmeier, Timothy G. Helentjaris
  • Publication number: 20030217393
    Abstract: The present invention provides a composition and method for regulating expression of heterologous nucleotide sequences in a plant. The method comprises transforming a plant cell to contain a heterologous nucleotide sequence operably linked to the stress-responsive promoter of the present invention and regenerating a stably transformed plant from the transformed plant cell.
    Type: Application
    Filed: February 12, 2003
    Publication date: November 20, 2003
    Applicants: Pioneer Hi-Bred International, Inc., North Carolina State University
    Inventors: Timothy G. Helentjaris, Hank W. Bass, Rebecca S. Boston
  • Publication number: 20030167528
    Abstract: The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase concentration and/or composition of plants. The invention further provides recombinant expression cassettes, host cells, and transgenic plants.
    Type: Application
    Filed: June 3, 2002
    Publication date: September 4, 2003
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Kanwarpal S. Dhugga, Timothy G. Helentjaris, Benjamin A. Bowen, Xun Wang
  • Publication number: 20030163839
    Abstract: The present invention provides methods and compositions relating to altering lignin biosynthesis content and/or composition of plants. The invention provides isolated nucleic acids and their encoded proteins which are involved in lignin biosynthesis. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
    Type: Application
    Filed: February 10, 2003
    Publication date: August 28, 2003
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Timothy G. Helentjaris, Benjamin A. Bowen, Xun Wang
  • Publication number: 20030163838
    Abstract: The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
    Type: Application
    Filed: July 31, 2002
    Publication date: August 28, 2003
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Kanwarpal S. Dhugga, Haiyin Wang, Dwight T. Tomes, Timothy G. Helentjaris
  • Publication number: 20030150014
    Abstract: The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
    Type: Application
    Filed: October 9, 2002
    Publication date: August 7, 2003
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Kanwarpal S. Dhugga, Timothy G. Helentjaris
  • Publication number: 20030140381
    Abstract: Compositions and methods for modulating gene expression in plants are provided. The compositions comprise novel genes and promoters as well as regulatory and binding elements therein. The methods comprise the modulation of gene expression using the compositions of the invention. Compositions and methods are provided to reduce the impact on plants of biotic and abiotic environmental stresses. Accordingly, the compositions and methods may also be used to decrease the necessary amounts of conventional stress reduction treatment as well as to increase plant yield.
    Type: Application
    Filed: December 19, 2002
    Publication date: July 24, 2003
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Nicholas J. Bate, Timothy G. Helentjaris, Xiping Niu
  • Publication number: 20030126638
    Abstract: The preparation and use of nucleic acid fragments useful in altering the oil phenotype in plants are disclosed. Recombinant DNA construct incorporating such nucleic acid fragments and suitable regulatory sequences can be used to create transgenic plants having altered lipid profiles. Methods for altering the oil phenotype in plants using such nucleic acid fragments also are disclosed.
    Type: Application
    Filed: June 26, 2002
    Publication date: July 3, 2003
    Inventors: William B. Allen, Rebecca E. Cahoon, Omolayo O. Famodu, Leslie T. Harvell, Timothy G. Helentjaris, Changjiang Li, Keith S. Lowe, Igor Cunha Oliveira, Bo Shen, Mitchell C. Tarczynski
  • Publication number: 20030005482
    Abstract: The invention provides a novel isolated sucrose synthase nucleic acid and its encoded protein. The present invention also provides methods and compositions relating to altering sucrose synthase levels in plants, and in particular, in plant stalks and/or plant seeds. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
    Type: Application
    Filed: February 21, 2002
    Publication date: January 2, 2003
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Kanwarpal S. Dhugga, Timothy G. Helentjaris, Xiaomu Niu
  • Publication number: 20020199217
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a sugar transport protein, more specifically an Arabidopsis-like or Beta-vulgaris-like sugar transport protein. The invention also relates to the construction of a recombinant DNA construct encoding all or a portion of the sugar transport protein, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels of the Arabidopsis-like or Beta-vulgaris-like sugar transport protein in a transformed host cell.
    Type: Application
    Filed: January 17, 2002
    Publication date: December 26, 2002
    Inventor: Timothy G. Helentjaris
  • Patent number: 6472185
    Abstract: Methods of genotyping amplified mixtures of DNAs, nucleic acid markers and methods of obtaining markers, kits, recombinant plants, positional cloning and integrated systems for making genotypes and assessing hybridizations are provided. These features are applicable to DNA fingerprinting, marker assisted selection, genotyping, cladistic analysis of variance, and high throughput laboratory screening methods.
    Type: Grant
    Filed: May 25, 2000
    Date of Patent: October 29, 2002
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Rhonda J. McCasky Feazel, Timothy G. Helentjaris, Sharon E. Malmberg, Barry A. Martin
  • Publication number: 20020120125
    Abstract: The present invention relates to polycomb genes and polypeptides isolated from Zea mays.
    Type: Application
    Filed: July 16, 2001
    Publication date: August 29, 2002
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Shawn M. Kaeppler, Nathan M. Springer, Timothy G. Helentjaris, Ronald L. Phillips
  • Publication number: 20010044941
    Abstract: Methods and compositions for increasing yield in plants, particularly seed plants, are provided. The compositions comprise novel nucleic acid molecules encoding invertase inhibitors, antisense nucleotides corresponding to invertase inhibitors, and variants and fragments thereof. Such compositions find use in methods to modulate invertase activity in plants. The compositions are also useful in methods to modulate kernel development and for protecting plants against the harmful/detrimental effects of stress and adverse environmental conditions. The nucleotide sequences may be provided in constructs for temporal, developmental, and tissue preference.
    Type: Application
    Filed: February 9, 2001
    Publication date: November 22, 2001
    Inventors: Timothy G. Helentjaris, Nicholas J. Bate, Stephen M. Allen
  • Publication number: 20010034059
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a GRR1 homolog. The invention also relates to the construction of a chimeric gene encoding all or a portion of the GRR1 homolog, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the GRR1 homolog in a transformed host cell.
    Type: Application
    Filed: December 1, 2000
    Publication date: October 25, 2001
    Inventors: Stephen M. Allen, Timothy G. Helentjaris
  • Patent number: 6100030
    Abstract: Methods of genotyping amplified mixtures of DNAs, nucleic acid markers and methods of obtaining markers, kits, recombinant plants, positional cloning and integrated systems for making genotypes and assessing hybridizations are provided. These features are applicable to DNA fingerprinting, marker assisted selection, genotyping, cladistic analysis of variance, and high throughput laboratory screening methods.
    Type: Grant
    Filed: January 9, 1998
    Date of Patent: August 8, 2000
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Rhonda J. McCasky Feazel, Timothy G. Helentjaris, Sharon E. Malmberg, Barry A. Martin