Abstract: In various embodiments, systems and methods are provided for increasing the likelihood of a sustained virological response or “cure” using a model of patient physiology incorporating a subjects race, gender, age, weight, concomitant medicines and disease state, immune response status, and responsiveness to drug therapies to simultaneously characterize the change in viral burden in the subject in terms of velocity of viral load decline. In an embodiment, once viral load in a subject is below a physical measurement limit, the model can extrapolate the subject's observed viral velocity toward a physiological target shown to be highly correlated with “cure.” In further embodiments, the model can be used for personalized medicine—“the right drug at the right dose for the right treatment duration for the right patient.” Accordingly, the model can provide optimal value for treatment and reducing the high cost of side effects.

Abstract: Disclosed herein is a method of making a corresponding lenticular image comprising: providing an output device in communication with a computer having a memory; receiving into the computer memory an interlaced image file; converting the interlaced image file into an output having an output resolution; varying the resolution of the output to define a varied output resolution; and creating a corresponding lenticular image using the output at the varied output resolution. In a preferred embodiment, the output device is a plate setter and the output is a plate. As such, in at least one embodiment, the method is suitable for use with a Computer-to-Plate (“CTP”) system.

Abstract: A method of producing a multidimensional image is disclosed. A plurality of planar images is layered in a desired sequence. A matrical image file is formed from the layered planar images and then printed. The resolution of the final matrical image is separate in both the X- and Y-directions, which provides for a high level of resolution for both movement and 3-D effects in the image.

Abstract: The present invention provides a lenticular lens and method for manufacturing the lens, and in particular when the lens is a lenticular lens web, such that finishing operations (e.g., cutting, laminating, etc.) and various end-use applications of the lens (e.g., labeling) can be achieved or accommodated in-line with the manufacture of the lens web. A lenticular pattern-forming device comprising a housing that is rotatable about a central longitudinal axis is disclosed. The housing has an outer surface having a groove pattern. The groove pattern includes circumferentially and longitudinally extending grooves on the outer surface and the grooves have substantially equal groove widths. The longitudinally extending grooves are substantially parallel with the central longitudinal axis and grooves cover the outer surface of the housing.

Abstract: Disclosed herein is a digitally imaged lenticular product comprising a lenticular lens having an array of lenticules defining a front surface, and a substantially flat back surface located opposite the front surface. The product further includes a digitally output interlaced image digitally printed and joined to the flat back surface of the lens so as to be in correspondence with the array of lenticules. The digitally output interlaced image includes at least one individually customizable element. The digitally imaged lenticular products can be part of a variety of consumer end products, such as a container, a cup, a label, and a package. This permits final digitally imaged lenticular products to have a wide range of variance and versions, both from one lenticular run to the next, as well as within a run, thereby accommodating individualized data.

Abstract: Disclosed herein is a method for determining a lenticular lens resolution for use in digital press printing. The method comprises determining a digital press machine resolution d, setting a master interlaced image resolution m for a master interlaced image such that the master interlaced image resolution is equal to the machine resolution, setting a number of frames f to be included in the master interlaced image, and determining a lenticular lens resolution L according to the relationship L=d/f. The result is a digitally output lenticular image that can be have many applications, including use in products such as containers, packages, labels, and the like. The selection process accounts for variations in digital press machine resolutions, lenticular lens resolution variations, various screening algorithms, to yield a high quality, commercial-grade digitally output lenticular image.

Abstract: Disclosed herein is a digitally imaged lenticular product comprising a lenticular lens having an array of lenticules defining a front surface, and a substantially flat back surface located opposite the front surface. The product further includes a digitally output interlaced image digitally printed and joined to the flat back surface of the lens so as to be in correspondence with the array of lenticules. The digitally output interlaced image includes at least one individually customizable element. The digitally imaged lenticular products can be part of a variety of consumer end products, such as a container, a cup, a label, and a package. This permits final digitally imaged lenticular products to have a wide range of variance and versions, both from one lenticular run to the next, as well as within a run, thereby accommodating individualized data.

Abstract: Disclosed herein is a digitally imaged lenticular product having a special effect feature. The product comprises a lenticular lens having an array of lenticules defining a front surface, and a substantially flat back surface located opposite the front surface. The product further comprises a digitally output interlaced image having a special effect feature, the image joined to the flat back surface of the lens so as to be in correspondence with the array of lenticules. Also disclosed is A digital dual-imaged lenticular product having an intermediate coating layer. Here, product comprises a lenticular lens having an array of lenticules defining a front surface, and a substantially flat back surface located opposite the front surface, a digitally output interlaced image having a first surface that is joined to the flat back surface of the lens and second surface that is opposite the first surface, the digitally output interlaced image in correspondence with the array of lenticules.

Abstract: Disclosed herein is a method for determining a lenticular lens resolution for use in digital press printing. The method comprises determining a digital press machine resolution d, setting a master interlaced image resolution m for a master interlaced image such that the master interlaced image resolution is equal to the machine resolution, setting a number of frames f to be included in the master interlaced image, and determining a lenticular lens resolution L according to the relationship L=d/f. The result is a digitally output lenticular image that can be have many applications, including use in products such as containers, packages, labels, and the like. The selection process accounts for variations in digital press machine resolutions, lenticular lens resolution variations, various screening algorithms, to yield a high quality, commercial-grade digitally output lenticular image.