Abstract: Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.

Abstract: An apparatus for cleaning a surface, the apparatus including a body defining a chamber, an inlet for liquid flow into the chamber, an outlet for liquid flow from the chamber, a nozzle connected to the outlet for generating an output flow of liquid for cleaning a surface, an acoustic transducer associated with the body to introduce acoustic energy into the liquid within the chamber whereby the acoustic energy is present in the liquid flowing out of the nozzle, and a gas bubble generator for generating gas bubbles within the liquid flowing out of the nozzle.

Abstract: An apparatus for cleaning a surface, the apparatus including a body defining a chamber, an inlet for liquid flow into the chamber, an outlet for liquid flow from the chamber, a nozzle connected to the outlet for generating an output flow of liquid for cleaning a surface, an acoustic transducer associated with the body to introduce acoustic energy into the liquid within the chamber whereby the acoustic energy is present in the liquid flowing out of the nozzle, and a gas bubble generator for generating gas bubbles within the liquid flowing out of the nozzle.

Abstract: Disclosed is a SONAR system operable to transmit a pair of pulses including an up-chirp signal and a down-chirp signal wherein the down-chirp signal is a time-reversed version of the up-chirp signal. Also disclosed is a related method of operation.

Abstract: An apparatus for cleaning a surface includes a body defining a cavity and terminating in a distal end that is adapted, in use, to be in the vicinity of a surface to be cleaned such that the surface forms an end wall of a chamber including the cavity; at least one cleaning liquid inlet for flow of a cleaning liquid into the chamber; a divider located in or at the end of the cavity that divides the chamber into first and second portions, the second portion, in use, being in fluid communication with the surface to be cleaned; and an acoustic transducer associated with the first portion to introduce acoustic energy into the chamber; wherein the divider is adapted to permit the passage of acoustic energy therethrough from the first portion to the second portion of the chamber to thereby allow pressure fluctuations to be generated at the surface.

Abstract: An apparatus includes a conical body defining a chamber configured to contain a liquid and having a nozzle located a front end of the conical body and configured to discharge a stream of the liquid, a rear wall positioned at a rear of the conical body and at least partially defining the chamber, an inlet in communication with the chamber for introducing the liquid into the chamber, an acoustic transducer positioned at the rear wall, the acoustic transducer configured to generate acoustic energy and to introduce the acoustic energy into the liquid contained in the chamber, and an exhaust system including a vent in communication with the chamber to remove a mixture of liquid and gas bubbles from the chamber, an exhaust leading away from the vent, and an outlet in communication with the exhaust and configured to discharge the liquid and gas bubbles into or adjacent to the stream.

Abstract: An apparatus and method for prevention and treatment of marine biofouling on a surface to be treated by the apparatus includes a body defining a cavity, the body terminating in a distal open end that is adapted, in use, to be in the vicinity of a surface to be treated such that the surface forms a first end wall of a chamber within the cavity; an acoustic transducer mounted within the cavity to form an opposite second end wall of the chamber, the acoustic transducer being adapted to cause acoustic pressure fluctuations; and a reservoir for a liquid, the reservoir including an inlet passage and a plurality of mutually spaced outlet passages for liquid flow from the reservoir into the chamber, the outlet passages at least partially surrounding the chamber in the vicinity of the distal open end.

Abstract: An apparatus for cleaning a surface includes a body defining a cavity and terminating in a distal end that is adapted, in use, to be in the vicinity of a surface to be cleaned such that the surface forms an end wall of a chamber including the cavity; at least one cleaning liquid inlet for flow of a cleaning liquid into the chamber; a divider located in or at the end of the cavity that divides the chamber into first and second portions, the second portion, in use, being in fluid communication with the surface to be cleaned; and an acoustic transducer associated with the first portion to introduce acoustic energy into the chamber; wherein the divider is adapted to permit the passage of acoustic energy therethrough from the first portion to the second portion of the chamber to thereby allow pressure fluctuations to be generated at the surface.

Abstract: Disclosed is a SONAR system operable to transmit a pair of pulses including an up-chirp signal and a down-chirp signal wherein the down-chirp signal is a time-reversed version of the up-chirp signal. Also disclosed is a related method of operation.

Abstract: An apparatus and method for cleaning a surface, the apparatus comprising: a body defining a cavity, the body terminating in a distal end that is adapted, in use, to be in the vicinity of a surface to be cleaned such that the surface to be cleaned forms an end wall of a chamber including the cavity; at least one cleaning liquid inlet for flow of a cleaning liquid into the chamber; a divider located in or at the end of the cavity that divides the chamber into a first portion and a second portion, the second portion, in use, being in fluid communication with the surface to be cleaned; and an acoustic transducer associated with the first portion of the chamber to introduce acoustic energy into the chamber; wherein the divider is adapted to permit the passage of acoustic energy therethrough from the first portion of the chamber to the second portion of the chamber to thereby allow pressure fluctuations to be generated at the surface to be cleaned.

Abstract: An insert is provided for use on industry standard gratings to prevent wear and damage to rigging ropes passing through the insert.

Abstract: The invention provides binding agents and assays tor insulin signal peptide. The agents and assays are useful in methods tor predicting, diagnosing, assessing or monitoring acute cardiac disorders, glucose handling disorders and diabetes in a subject. Also provided are nucleotides, polypeptides, and kits useful in the methods of the invention.

Abstract: An apparatus and method for cleaning a surface, the apparatus comprising: a body defining a cavity, the body terminating in a distal end that is adapted, in use, to be in the vicinity of a surface to be cleaned such that the surface to be cleaned forms an end wall of a chamber including the cavity; at least one cleaning liquid inlet for flow of a cleaning liquid into the chamber; a divider located in or at the end of the cavity that divides the chamber into a first portion and a second portion, the second portion, in use, being in fluid communication with the surface to be cleaned; and an acoustic transducer associated with the first portion of the chamber to introduce acoustic energy into the chamber; wherein the divider is adapted to permit the passage of acoustic energy therethrough from the first portion of the chamber to the second portion of the chamber to thereby allow pressure fluctuations to be generated at the surface to be cleaned.

Abstract: The invention provides binding agents and assays tor insulin signal peptide. The agents and assays are useful in methods tor predicting, diagnosing, assessing or monitoring acute cardiac disorders, glucose handling disorders and diabetes in a subject. Also provided are nucleotides, polypeptides, and kits useful in the methods of the invention.

Abstract: An insert is provided for use on industry standard gratings to prevent wear and damage to rigging ropes passing through the insert.

Abstract: A system for securing at least two heating, ventilation, and air conditioning units stacked on each other for transportation includes corner brackets on at least the four corners of the lower unit and between the units. Each corner bracket has a banding channel, a plank-receiving channel, and a plurality of protrusions on a top side. The brackets are banded in place using the banding channels. On each longitudinal side, planks are used to extend between corner brackets to help control the loads and to distribute the loads. The corner brackets may be made from a synthetic material and the planks from wood or wood-like material. Other aspects are disclosed.

Abstract: The invention provides binding agents and assays for insulin signal peptide. The agents and assays are useful in methods for predicting, diagnosing, assessing or monitoring acute cardiac disorders, glucose handling disorders and diabetes in a subject. Also provided are nucleotides, polypeptides, and kits useful in the methods of the invention.

Abstract: The invention provides methods for predicting, diagnosing or monitoring acute cardiac disorders, cardiac transplant rejection, or distinguishing acute cardiac disorders from pulmonary disorders, by measuring BNP signal peptide levels in a sample taken from a subject shortly after onset of, or presentation with the disorder or transplant rejection.

Abstract: The present invention provides an apparatus for supporting stacking of a top heating, ventilation, and air conditioning (HVAC) unit on top of a bottom HVAC unit. The apparatus includes a base member configured to mount to a top cover of the bottom HVAC unit. The base member comprises an upper base portion with a top surface configured to receive at least a portion of a base rail of the top HVAC unit. The apparatus further comprises a stacking insert extending away from the base member. The stacking insert has one or more sloped surfaces extending above the top surface of the upper base portion. The top surface extends from a base of the one or more sloped surfaces in a plane substantially parallel to the top cover, when the base member is mounted to the top cover of the bottom HVAC unit.

Abstract: The invention provides methods for predicting, diagnosing or monitoring acute cardiac disorders, cardiac transplant rejection, or distinguishing acute cardiac disorders from pulmonary disorders, by measuring BNP signal peptide levels in a sample taken from a subject shortly after onset of, or presentation with the disorder or transplant rejection.