Patents by Inventor Timothy Grieme

Timothy Grieme has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fused bicyclic-substituted amines as histamine-3 receptor ligands
    Publication number: 20040248899
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: April 30, 2004
    Publication date: December 9, 2004
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach
  • Process for preparing amine-substituted benzofurans
    Patent number: 6822101
    Abstract: The present invention relates to processes for preparing amine substituted benzofurans, and more particularly 4-(2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile, and salts thereof. Compounds prepared by the processes of the invention have demonstrated activity as histamine-3 receptor ligands.
    Type: Grant
    Filed: September 5, 2003
    Date of Patent: November 23, 2004
    Assignee: Abbott Laboratories
    Inventors: Yi-Yin Ku, Yu-Ming Pu, Marlon D. Cowart, Timothy A. Grieme, Ashok K. Gupta, Daniel J. Plata
  • Fused bicyclic-substituted amines as histamine-3 receptor ligands
    Publication number: 20040224953
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: September 25, 2003
    Publication date: November 11, 2004
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach
  • Fused bicyclic-substituted amines as histamine-3 receptor ligands
    Publication number: 20040224952
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: May 7, 2003
    Publication date: November 11, 2004
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach
  • Fused cycloalkyl amides and acids and their therapeutic applications
    Publication number: 20040209859
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: October 22, 2003
    Publication date: October 21, 2004
    Inventors: Youssef L. Bennani, Sou-Jen Chang, Sanjay R. Chemburkar, Michael J. Dart, Dilinie P. Fernando, Timothy A. Grieme
  • Process for preparing amine-substituted benzofurans
    Publication number: 20040133007
    Abstract: The present invention relates to processes for preparing amine substituted benzofurans, and more particularly 4-(2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile, and salts thereof. Compounds prepared by the processes of the invention have demonstrated activity as histamine-3 receptor ligands.
    Type: Application
    Filed: September 5, 2003
    Publication date: July 8, 2004
    Inventors: Yi-Yin Ku, Yu-Ming Pu, Marlon D. Cowart, Timothy A. Grieme, Ashok K. Gupta, Daniel J. Plata
  • Fused cycloalkyl amides and acids and their therapeutic applications
    Publication number: 20040077617
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: October 22, 2002
    Publication date: April 22, 2004
    Inventors: Youssef L. Bennani, Sou-Jen Chang, Sanjay R. Chemburkar, Michael J. Dart, Dilinie P. Fernando, Timothy A. Grieme
  • Process for preparing amine-substituted benzofurans
    Publication number: 20040054185
    Abstract: The present invention relates to processes for preparing amine substituted benzofurans, and more particularly 4-(2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile, and salts thereof. Compounds prepared by the processes of the invention have demonstrated activity as histamine-3 receptor ligands.
    Type: Application
    Filed: July 2, 2003
    Publication date: March 18, 2004
    Inventors: Marlon D. Cowart, Yu-Ming Pu, Yi-Yin Ku, Timothy A. Grieme, Ashok K. Gupta, Daniel J. Plata, Ramin Faghih, Gregory A. Gfesser
  • Process for the preparation of 5-(substituted)-10 methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno [3,4-F] quinolines and derivatives thereof
    Patent number: 6673930
    Abstract: The present invention relates to an efficient process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinolines.
    Type: Grant
    Filed: November 7, 2002
    Date of Patent: January 6, 2004
    Inventors: Yi-Yin Ku, Timothy A. Grieme, Padam N. Sharma, Prasad S. Raje, Howard E. Morton, Mike A. Fitzgerald
  • Process for the preparation of 5-(substituted)-10 methoxy-2,2,4-trimethyl-2,5-dihydro- 1H-chromeno [3,4-f] quinolines and derivatives thereof
    Publication number: 20030069427
    Abstract: The present invention relates to an efficient process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinolines.
    Type: Application
    Filed: November 7, 2002
    Publication date: April 10, 2003
    Inventors: Yi-Yin Ku, Timothy A. Grieme, Padam N. Sharma, Prasad S. Raje, Howard E. Morton, Mike A. Fitzgerald
  • Process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-F]quinolines and derivatives thereof
    Patent number: 6518430
    Abstract: The present invention relates to an efficient process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinolines.
    Type: Grant
    Filed: September 21, 2001
    Date of Patent: February 11, 2003
    Assignee: Abbott Laboratories
    Inventors: Yi-Yin Ku, Timothy A. Grieme, Padam N. Sharma, Prasad S. Raje, Howard E. Morton, Mike A. Fitzgerald