Abstract: Methods, systems and computer-readable storage media relate to image-guided treatment planning and treatment assessment. The methods, systems, and the computer-readable storage medias according to embodiments can analyze treatment response and can determine an accurate, outcome-based response assessment of treatment (e.g., radiation treatment). The methods may include a method for determining a treatment response. The method may include registering at least a first image data and a second image data of a subject, the first image data corresponding to a first time point, the second image data corresponding to a second time point, the first time point and the second time point being different with respect to a treatment session and/or treatment stage. The method may include processing the registered image to determine a treatment response. The registering may be based on deformable registration.

Abstract: Methods, systems and computer-readable storage media relate to generating a treatment plan for a patient having a patient record. The methods, systems, and the computer-readable storage medias according to embodiments can automatically generate a treatment plan for the patient using (reference) records from previous plans. The system may include: a comparison module configured to compare anatomical information of a plurality of reference records and the patient record; a comparison quantification module configured to determine a metric corresponding to a degree of matching between each reference record and patient record; a reference record selection module configured to select a reference record from the plurality of reference records based on the metric; and a treatment plan generation module configured to generate a treatment plan for the patient based on the selected reference record.

Abstract: Methods, systems and computer-readable storage media relate to image-guided treatment planning and treatment assessment. The methods, systems, and the computer-readable storage medias according to embodiments can analyze treatment response and can determine an accurate, outcome-based response assessment of treatment (e.g., radiation treatment). The methods may include a method for determining a treatment response. The method may include registering at least a first image data and a second image data of a subject, the first image data corresponding to a first time point, the second image data corresponding to a second time point, the first time point and the second time point being different with respect to a treatment session and/or treatment stage. The method may include processing the registered image to determine a treatment response. The registering may be based on deformable registration.

Abstract: A system and method for the prevention of restenosis uses a source of radiation to treat the blood vessel. An intra-vascular ultrasound system acquires precise two-dimensional images of a treatment volume. The intra-vascular ultrasound system enables medical personnel to obtain precise measurements of the distance between the radiation source and the lesion. Whereas conventional techniques for measuring this distance relied upon external imaging devices, the intra-vascular ultrasound system obtains in-vivo images allowing precise measurements to be taken at the point at which the radiation will be delivered. A computer-based treatment planner acquires the images from the imaging system and reconstructs a three-dimensional image of the treatment volume. From a dose prescription, the treatment planner calculates and optimizes the dose and also registers the dose with images of the treatment volume. A voice recognition unit allows medical personnel to provide voice commands for operating the system.

Abstract: A system and method for the prevention of restenosis uses a source of radiation to treat the blood vessel. An intra-vascular ultrasound system acquires precise two-dimensional images of a treatment volume. The intra-vascular ultrasound system enables medical personnel to obtain precise measurements of the distance between the radiation source and the lesion. Whereas conventional techniques for measuring this distance relied upon external imaging devices, the intra-vascular ultrasound system obtains in-vivo images allowing precise measurements to be taken at the point at which the radiation will be delivered. A computer-based treatment planner acquires the images from the imaging system and reconstructs a three-dimensional image of the treatment volume. From a dose prescription, the treatment planner calculates and optimizes the dose and also registers the dose with images of the treatment volume. A voice recognition unit allows medical personnel to provide voice commands for operating the system.