Abstract: The present invention is directed to methods of purifying viral proteins for use in vaccine compositions. The method includes a capture step and a polish step. The capture step includes passing a solution containing a protein over a hydrophobic interaction chromatography column and eluting a crude protein eluate from the column. The polish step includes passing the crude protein eluate over a ligand affinity chromatography column and recovering a first flow through intermediate, passing the first flow through intermediate over an anion exchange chromatography column and recovering a second flow through intermediate, and passing the second flow through intermediate over another ligand affinity chromatography column and recovering a purified protein eluate. The present invention also provides a purified protein having a hydrophobic membrane domain that is produced by a baculovirus expression system in cultured insect cells, wherein the purified protein has a purity of greater than 85%.

Abstract: A grinding machine for grinding food-products, such as meat or the like, includes an orifice plate at the outlet of a grinding head. The orifice plate has collection passages that discharge a mixture of soft material and hard material through the orifice plate. A separator assembly, including a separator screw, separation chamber, metering auger, and metering cone, is located downstream of the orifice plate for separating the soft material from the hard material. The metering auger is fixedly coupled to a distal end of the separator screw and has a reduced diameter relative to the separator screw. The metering auger advances in a downstream direction the hard material of the mixture of soft material and hard material.

Abstract: A grinding machine for grinding food-products, such as meat or the like, includes an orifice plate at the outlet of a grinding head. The orifice plate has collection passages that discharge a mixture of soft material and hard material through the orifice plate. A separator assembly, including a separator screw and separation chamber, is located downstream of the orifice plate for separating the soft material from the hard material. A ring adjustment assembly includes a ring valve having an internal conical portion in communication with a nose portion of the separator screw, and a ring valve carrier configured to reciprocally displace the ring valve in an axial direction relative to the separator screw so as to vary a gap between the nose portion of the separator screw and the internal conical portion of the ring valve. Adjustment of the gap distance determines an amount of the hard material that is passed toward the discharge outlet.

Abstract: A grinding machine for grinding food-products, such as meat or the like, includes an orifice plate at the outlet of a grinding head. The orifice plate has collection passages that discharge a mixture of soft material and hard material through the orifice plate. A separator assembly, including a separator screw and separation chamber, is located downstream of the orifice plate for separating the soft material from the hard material. A ring adjustment assembly includes a ring valve having an internal conical portion in communication with a nose portion of the separator screw, and a ring valve carrier configured to reciprocally displace the ring valve in an axial direction relative to the separator screw so as to vary a gap between the nose portion of the separator screw and the internal conical portion of the ring valve. Adjustment of the gap distance determines an amount of the hard material that is passed toward the discharge outlet.

Abstract: A grinding machine for grinding food-products, such as meat or the like, includes an orifice plate at the outlet of a grinding head. The orifice plate has collection passages that discharge a mixture of soft material and hard material through the orifice plate. A separator assembly, including a separator screw, separation chamber, metering auger, and metering cone, is located downstream of the orifice plate for separating the soft material from the hard material. The metering auger is fixedly coupled to a distal end of the separator screw and has a reduced diameter relative to the separator screw. The metering auger advances in a downstream direction the hard material of the mixture of soft material and hard material.

Abstract: Embodiments of the invention are directed to systems that detect maliciously formed TCP/IP retransmit packets attempting to pass through an intrusion detection system (IDS) and prevent them from reaching their destination by forcing early flow termination. The IDS may be configured to track a hash of certain fields in each packet. This set of hashes is maintained for all of the packets in the currently open TCP window for each flow. If the hash of a retransmit packet does not match the cached hash of the corresponding original packet, the system concludes that there is an attack under way and terminates the flow. The hash function may range in complexity and security from low complexity and relative insecurity to high complexity and high security. Hash algorithms may also be used in conjunction with a private seed value concatenated with the packet fields prior to hashing.

Abstract: Embodiments of the present invention address deficiencies of the art in respect to access control and provide a method, system and computer program product for access control management for a collection of heterogeneous application components. In a first embodiment, a data processing system for role-based access control management for multiple heterogeneous application components can include at least one business role descriptor associating a business role with multiple, different application roles for corresponding, disparate application components. The system also can include at least one access policy associating a user with the business role. Finally, the system can include policy deployment logic include program code enabled to process the access policy to assign the user to the different application roles in the disparate application components.

Abstract: An authenticated identity propagation and translation technique is provided based on a trust relationship between multiple user identification and authentication services resident on different computing components of a multi-component transaction processing computing environment including distributed and mainframe computing components. The technique includes, in one embodiment, forwarding, in association with transaction requests, identified and authenticated user identification and authentication information from a distributed component to a mainframe component, facilitating the selection of the appropriate mainframe user identity with which to execute the mainframe portion of the transaction, and creating the appropriate run-time security context.