Patents by Inventor Timothy J. Barberich

Timothy J. Barberich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5648396
    Abstract: A method and composition are utilizing the pure R(-) isomer of fluoxetine which is a potent antidepressant and appetite suppressant substantially free of adverse effects. In addition, a method and composition are disclosed utilizing the pure R(-) isomer of fluoxetine which is useful to treat migraine headaches, pain, in particular chronic pain, psychoactive substance abuse disorders and obsessive compulsive disorders.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 15, 1997
    Assignee: Sepracor Inc.
    Inventors: James W. Young, Timothy J. Barberich, Martin H. Teicher
  • Patent number: 5589511
    Abstract: Methods and compositions are disclosed utilizing the pure S(+) isomer of fluoxetine which is a potent antidepressant and appetite suppressant substantially free of unwanted, adverse toxic or psychological effects. In addition, methods and compositions are disclosed utilizing the pure S(+) isomer of fluoxetine which is useful in treating migraine headaches, pain, in particular chronic pain, obsessive-compulsive disorders, sexual dysfunction and memory disorders. Further, methods and compositions for treating a condition alleviated or improved by inhibition of serotonin uptake in serotonergic neurons and platelets in a human using optically pure S(+) fluoxetine are disclosed.
    Type: Grant
    Filed: April 15, 1994
    Date of Patent: December 31, 1996
    Assignee: Sepracor Inc.
    Inventors: James W. Young, Timothy J. Barberich
  • Patent number: 5571827
    Abstract: Methods and compositions are disclosed utilizing the optically pure S(-) isomer of nitrendipine. This compound is a potent drug for the treatment of hypertension while avoiding the concomitant liability of adverse effects associated with the administration of the racemic mixture of nitrendipine. The S(-) isomer of nitrendipine is also useful for the treatment of angina and such other conditions as may be related to the activity of S(-) nitrendipine as a calcium channel antagonist without the concomitant liability of adverse effects associated with the racemic mixture of nitrendipine.
    Type: Grant
    Filed: June 15, 1994
    Date of Patent: November 5, 1996
    Assignee: Sepracor Inc.
    Inventors: Timothy J. Barberich, James W. Young
  • Patent number: 5547994
    Abstract: The optically pure R(-) isomer of albuterol, which is substantially free of the S(+) isomer, is a potent bronchodilator for relieving the symptoms associated with asthma in individuals. A method is disclosed utilizing the optically pure R(-) isomer of albuterol for treating asthma while minimizing the side effects associated with albuterol.
    Type: Grant
    Filed: November 7, 1994
    Date of Patent: August 20, 1996
    Assignee: Sepracor, Inc.
    Inventors: Timothy J. Barberich, James W. Young
  • Patent number: 5382591
    Abstract: Methods are disclosed utilizing optically pure R-ketorolac for the treatment of pain, including but not limited to pain associated with toothaches, headaches, sprains, joint pain and surgical pain, for example dental pain (e.g., after periodontal surgery) and ophthalmic pain (e.g., after cataract surgery) while avoiding adverse effects which are associated with the administration of the racemic mixture of ketorolac. The optically pure R-ketorolac is also useful in treating pyrexia while avoiding the adverse effects associated with the administration of the racemic mixture of ketorolac.
    Type: Grant
    Filed: September 8, 1993
    Date of Patent: January 17, 1995
    Assignee: Sepracor Inc.
    Inventors: Timothy J. Barberich, Stephen L. Matson, William J. Wechter
  • Patent number: 5362755
    Abstract: The optically pure R(-) isomer of albuterol, which is substantially free of the S(+) isomer, is a potent bronchodilator for relieving the symptoms associated with asthma in individuals. A method is disclosed utilizing the optically pure R(-) isomer of albuterol for treating asthma while minimizing the side effects associated with chronic administration of racemic albuterol.
    Type: Grant
    Filed: December 7, 1993
    Date of Patent: November 8, 1994
    Assignee: Sepracor, Inc.
    Inventors: Timothy J. Barberich, James W. Young
  • Patent number: 5362757
    Abstract: Optically pure (S) metoprolol, which is substantially free of the (R) enantiomer, is a potent beta-blocker for treating myocardial infarction and for relieving the symptoms of angina pectoris, cardiac arrhythmia and hypertension in individuals. A method is disclosed utilizing the optically pure (S) configurational enantiomer of metoprolol for treating cardiovascular disorders while reducing undesirable side effects associated with the administration of beta-blockers.
    Type: Grant
    Filed: November 16, 1992
    Date of Patent: November 8, 1994
    Assignee: Sepracor, Inc.
    Inventors: James W. Young, Timothy J. Barberich
  • Patent number: 5190962
    Abstract: The optically pure isomer of nitrendipine having anti-hypertensive activity, is a potent anti-hypertensive drug for reducing blood pressure in individuals without the undesirable side effects associated with administration of a racemic mixture of nitrendipine. A method is disclosed utilizing an optically pure isomer of nitrendipine for treating hypertension while reducing undesirable side effects associated with nitrendipine.
    Type: Grant
    Filed: March 13, 1990
    Date of Patent: March 2, 1993
    Assignee: Sepracor, Inc.
    Inventors: Timothy J. Barberich, James W. Young
  • Patent number: 5104899
    Abstract: A method and composition are disclosed utilizing the pure S(+) isomer of fluoxetine, which is a potent antidepressant substantially free of adverse toxic or psychological effects, having a rapid onset of action and a high response rate.
    Type: Grant
    Filed: August 13, 1990
    Date of Patent: April 14, 1992
    Assignee: Sepracor, Inc.
    Inventors: James W. Young, Timothy J. Barberich