Abstract: The present disclosure pertains to sample preparation devices useful for affinity capture and purification that include one or more internal structures that comprise a reservoir, a well, a fluid passageway, sorbent particles, and a filter element that blocks passage of the affinity sorbent particles, which sample preparation devices combine the attributes of both dispersive and flow through designs into a single sample preparation device. The present disclosure also pertains to kits that contain and methods that use such sample preparation devices.

Abstract: The present disclosure pertains to sample preparation devices useful for affinity capture and purification that include one or more internal structures that comprise a reservoir, a well, a fluid passageway, sorbent particles, and a filter element that blocks passage of the affinity sorbent particles, which sample preparation devices combine the attributes of both dispersive and flow through designs into a single sample preparation device. The present disclosure also pertains to kits that contain and methods that use such sample preparation devices.

Abstract: A pressurized fluid turbulence system includes a component inlet that receives a liquid component, component outlet for expelling the liquid component and an adjustable ball valve arranged between and in fluid communication with the component inlet and component outlet, and can open and close a flow path between the two. The component inlet and outlet both have a cylindrical channel and the component inlet is upstream from the component outlet. A cylindrically shaped pressurized input receives a pressurized fluid and has a longitudinal axis aligned in a direction towards the adjustable ball valve such that a pressurized fluid may impact the adjustable ball valve when the pressurized input is in an open position. A system for mixing two liquid components includes two pressurized fluid turbulence systems in which the two liquid components are mixed downstream of the component outlets.

Abstract: An expansible shaft assembly has core-engagement shoes pivotally mounted to a shaft for pivoting outwardly into tight engagement with the interior of a roll core automatically in response to the application of torque to the shaft. The core-engagement shoes have core-engaging surfaces, some being pivotable outwardly in response to torque applied to the shaft in one axial direction and others being pivotable outwardly in response to torque applied in the opposite axial direction. The respective oppositely-actuated core-engaging surfaces can both be on the same engagement shoe or, alternatively, on different shoes spaced axially along the shaft. For maximizing the speed with which the core-engagement shoes engage the core in response to torque application, the core-engaging surfaces are preferably angularly offset significantly from a radial direction extending between the axis of rotation of the shaft and the pivot axis of the engagement shoe.

Abstract: An elongate expansible shaft for a roll core has a peripheral surface defining multiple separate elongate slots helically intertwined and oriented at a pitch angle no greater than about 30.degree. measured from a longitudinal axis. Each slot is T-shaped in cross section and contains a respective separate, elongate, resilient bladder pneumatically expandable into frictional engagement with the core. The bladder has a unitary construction with hinge portions for minimizing the loss of force due to expansion of the bladder. An air inlet fitting is inserted in one end of each bladder and is independently connected to a respective separate valve for preventing the escape of air from the bladder irrespective of the air pressure in any other bladder.

Abstract: An elongate expansible shaft for a roll core has a peripheral surface defining multiple separate elongate slots helically intertwined and oriented at a pitch angle no greater than about 30.degree. measured from a longitudinal axis. Each slot is T-shaped in cross section and contains a respective separate, elongate, resilient T-shaped bladder pneumatically expandable into frictional engagement with the core. The bladder has a unitary construction with hinge portions for minimizing the loss of force due to expansion of the bladder. An air inlet fitting is inserted in one end of each bladder and is independently connected to a respective separate valve for preventing the escape of air from the bladder irrespective of the air pressure in any other bladder.