Abstract: Methods and apparatus are presented for flexibly building a dynamic report using a heterogeneous mix of dimensions, segments, and metrics. Within a report building tool a user may introduce any number of dimensions and segments at any point within a generated report. Further within the report building tool, a user may break down existing dimensions and segments within a report with nested dimensions and segments, which may be added without limits on a nesting level. Given a generated report, a user may pivot the generated report, where the pivot includes pivoting any heterogeneous combination of dimensions, segments, and metrics within the generated report defined along each axis. Further, the pivot operation maintains the relative groupings and nestings of dimensions, dimension items, segments, and metrics in going from a column to a row or from a row to a column.

Abstract: Methods and apparatus are presented for flexibly building a dynamic report using a heterogeneous mix of dimensions, segments, and metrics. Within a report building tool a user may introduce any number of dimensions and segments at any point within a generated report. Further within the report building tool, a user may break down existing dimensions and segments within a report with nested dimensions and segments, which may be added without limits on a nesting level. Given a generated report, a user may pivot the generated report, where the pivot includes pivoting any heterogeneous combination of dimensions, segments, and metrics within the generated report defined along each axis. Further, the pivot operation maintains the relative groupings and nestings of dimensions, dimension items, segments, and metrics in going from a column to a row or from a row to a column.

Abstract: Methods and apparatus are presented for flexibly building a dynamic report using a heterogeneous mix of dimensions, segments, and metrics. Within a report building tool a user may introduce any number of dimensions and segments at any point within a generated report. Further within the report building tool, a user may break down existing dimensions and segments within a report with nested dimensions and segments, which may be added without limits on a nesting level. Given a generated report, a user may pivot the generated report, where the pivot includes pivoting any heterogeneous combination of dimensions, segments, and metrics within the generated report defined along each axis. Further, the pivot operation maintains the relative groupings and nestings of dimensions, dimension items, segments, and metrics in going from a column to a row or from a row to a column.

Abstract: Methods and apparatus are presented for flexibly building a dynamic report using a heterogeneous mix of dimensions, segments, and metrics. Within a report building tool a user may introduce any number of dimensions and segments at any point within a generated report. Further within the report building tool, a user may break down existing dimensions and segments within a report with nested dimensions and segments, which may be added without limits on a nesting level. Given a generated report, a user may pivot the generated report, where the pivot includes pivoting any heterogeneous combination of dimensions, segments, and metrics within the generated report defined along each axis. Further, the pivot operation maintains the relative groupings and nestings of dimensions, dimension items, segments, and metrics in going from a column to a row or from a row to a column.

Abstract: The present invention provides the nucleotide sequence of the M antigen gene of H. capsulatum, which is set forth in the Sequence Listing as SEQ ID NO:1, a nucleic acid having the nucleotide sequence complementary thereto, and nucleic acids having a nucleotide sequence which is substantially the same as the foregoing nucleotide sequences. The present invention also provides vectors and host expressions systems containing the foregoing nucleic acids, and isolated or recombinantly-produced antigens encoded by the foregoing nucleic acids. The present invention further provides antibodies generated against the foregoing antigens, and methods and kits for detecting a previous or current Histoplasma capsulatum infection in a subject, and for diagnosing histoplasmosis.

Abstract: The nucleic acid sequence encoding the internal transcribed spacer 2 region of Candida, the organism causing candidiasis, for various Candida species. Nucleic acid molecules useful as probes for detecting Candida species are described. The nucleic acid molecules are useful in methods for the detection and diagnosis of Candida infection in a sample or subject.

Abstract: Provided is an isolated double-stranded nucleic acid consisting essentially of the nucleotide sequences defined in the Sequence Listing by SEQ ID Nos:5-9. These are the ITS2 sequences for C. albicans, C. parapsilosis, C. tropicalis, C. glabrata and C. krusei. A method of diagnosing systemic candidiasis in a subject is also provided. The method comprises the steps of: (a) collecting blood from the subject into tubes containing detergent, polypropylene glycol, sodium poyantholesulfonate, and sodium ethylene diamine tetraacetic acid; (b) lysing Candida cells using ZYMOLYASE.RTM.-100T.TM.

Abstract: Provided is an isolated double-stranded nucleic acid consisting essentially of the nucleotide sequences defined in the Sequence Listing by SEQ ID Nos: 5-9. These are the ITS2 sequences for C. albicans, C. parapsilosis, C. tropicalis, C. glabrata and C. krusei. A method of diagnosing systemic candidiasis in a subject is also provided. The method comprises the steps of: (a) collecting blood from the subject into tubes containing detergent, polypropylene glycol, sodium poyantholesulfonate, and sodium ethylene diamine tetraacetic acid; (b) lysing Candida cells using ZYMOLYASE.RTM.-100T with agitation; (c) extracting and precipitating the DNA from the lysed cells; (d) amplifying the precipitated DNA using universal fungal primer pairs derived from the internal transcribed spacer regions of the Candida ribosomal DNA; and (e) detecting amplified DNA from Candida by hybridizing the amplified DNA with a probe that selectively hybridizes with Candida DNA, the presence of amplified DNA indicating systemic candidiasis.

Abstract: Provided is an isolated double-stranded nucleic acid consisting essentially of the nucleotide sequences defined in the Sequence Listing by SEQ ID Nos:5-9. These are the ITS2 sequences for C. albicans, C. parapsilosis, C. tropicalis, C. glabrata and C. krusei. A method of diagnosing systemic candidiasis in a subject is also provided. The method comprises the steps of: (a) collecting blood from the subject into tubes containing detergent, polypropylene glycol, sodium poyantholesulfonate, and sodium ethylene diamine tetraacetic acid; (b) lysing Candida cells using ZYMOLYASE.RTM.-100T with agitation; (c) extracting and precipitating the DNA from the lysed cells; (d) amplifying the precipitated DNA using universal fungal primer pairs derived from the internal transcribed spacer regions of the Candida ribosomal DNA; and (e) detecting amplified DNA from Candida by hybridizing the amplified DNA with a probe that selectively hybridizes with Candida DNA, the presence of amplified DNA indicating systemic candidiasis.

Abstract: Provided is an isolated double-stranded nucleic acid consisting essentially of the nucleotide sequences defined in the Sequence Listing by SEQ ID NOs: 5-9. These are the ITS2 sequences for C. albicans, C. parapsilosis, C. tropicalis, C. glabrata and C. krusei. A method of diagnosing systemic candidiasis in a subject is also provided. The method comprises the steps of: (a) collecting blood from the subject into tubes containing detergent, polypropylene glycol, sodium poyantholesulfonate, and sodium ethylene diamine tetraacetic acid; (b) lysing Candida cells using ZYMOLYASE.RTM.-100T with agitation; (c) extracting and precipitating the DNA from the lysed cells; (d) amplifying the precipitated DNA using universal fungal primer pairs derived from the internal transcribed spacer regions of the Candida ribosomal DNA; and (e) detecting amplified DNA from Candida by hybridizing the amplified DNA with a probe that selectively hybridizes with Candida DNA, the presence of amplified DNA indicating systemic candidiasis.

Abstract: Provided is an isolated double-stranded nucleic acid consisting essentially of the nucleotide sequence defined in the Sequence Listing by SEQ ID NO:5. This is the C. albicans ITS2 sequence and includes a nucleic acid comprising a nucleotide sequence that is specific for Candida albicans. Further examples of an isolated double stranded nucleic acid of the present invention consist essentially of the nucleotide sequences defined in the Sequence Listing by SEQ ID NOs:6-9. These are the ITS2 sequences for C. parapsilosis, C. tropicalis, C. glabrata and C. krusei. A method of diagnosing systemic candidiasis in a subject is also provided. The method comprises the steps of: (a) collecting blood from the subject into tubes containing detergent, polypropylene glycol, sodium polyanetholesulfonate, and sodium ethylene diamine.RTM. tetraacetic acid; (b) lysing Candida cells using ZYMOLYASE.RTM.