Patents by Inventor Timothy J. McDonnell

Timothy J. McDonnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides
    Patent number: 7285288
    Abstract: The present invention provides novel compositions and methods for use in the treatment of Bcl-2-associated diseases like cancer, specifically, in the treatment of follicular lymphoma (FL). The compositions contain antisense oligonucleotides that hybridize to Bcl-2 nucleic acids, the gene products of which are known to interact with the tumorigenic protein Bcl-2. Used alone, or in conjunction with other antisense oligonucleotides, these compositions inhibit the proliferation of FL cancer cells.
    Type: Grant
    Filed: October 3, 1997
    Date of Patent: October 23, 2007
    Assignee: Board of Regents, the University of Texas System
    Inventors: Mar Tormo, Ana M Tari, Gabriel Lopez-Berestein, Timothy J McDonnell
  • Induction of apoptic or cytotoxic gene expression by adenoviral mediated gene codelivery
    Patent number: 6899870
    Abstract: The present invention generally relates to viral vectors and their use as expression vectors for transforming human cells, both in vitro and in vivo. More particularly, the present invention relates to adenoviral vectors containing propapoptotic genes and their use in cancer therapy.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: May 31, 2005
    Assignee: Board of Regents, The University of Texas System
    Inventors: Timothy J. McDonnell, Stephen G. Swisher, Bingliang Fang, Elizabeth M. Bruckheimer, Mona G. Sarkiss, Lin Ji, Jack A. Roth
  • Detachable bed legs
    Patent number: 5477571
    Abstract: A leg apparatus for convenient attachment to a conventional angle-brace bed frame such that the height of the bed may be increased thereby increasing the area for storage beneath and also for producing a more aesthetically pleasing appearance. The invention embodies one type of leg for attachment to the perimeter frame and a second type of leg for attachment to the frame cross-member.
    Type: Grant
    Filed: August 2, 1993
    Date of Patent: December 26, 1995
    Assignee: A-1 Manufacturing Corporation
    Inventors: Alvin W. Roggenkamp, Timothy J. McDonnell
  • Detachable bed legs
    Patent number: 5231713
    Abstract: A leg apparatus for convenient attachment to a conventional angle-brace bed frame such that the height of the bed may be increased thereby increasing the area for storage beneath and also for producing a more aesthetically pleasing appearance. The invention embodies one type of leg for attachment to the perimeter frame and a second type of leg for attachment to the frame cross-member.
    Type: Grant
    Filed: December 14, 1992
    Date of Patent: August 3, 1993
    Inventor: Timothy J. McDonnell