Abstract: A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.

Abstract: A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.

Abstract: A dispenser includes an upper member having a slot and a lower member attached to the upper member thereby forming a housing, the lower member having an outer surface; a stack of sheets assembled in a fan-fold configuration disposed in the housing; and a polymeric holding film having a first surface attached to the outer surface of the lower member. The holding film having a flexural modulus less than about 50 MPa, as measured according to ASTMD790 standard, and a roughness parameter, Ra of less than about 1 micrometer, as calculated according to ASME B46.1 standard.

Abstract: A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.

Abstract: A dispenser includes an upper member having a slot and a lower member attached to the upper member thereby forming a housing, the lower member having an outer surface; a stack of sheets assembled in a fan-fold configuration disposed in the housing; and a polymeric holding film having a first surface attached to the outer surface of the lower member. The holding film having a flexural modulus less than about 50 MPa, as measured according to ASTMD790 standard, and a roughness parameter, Ra of less than about 1 micrometer, as calculated according to ASME B46.1 standard.

Abstract: A chlorine dioxide solution generator, which injects a chlorine dioxide solution into a pressurized fluid system, including an absorption loop for effecting the dissolution of chlorine dioxide into a liquid stream. The chlorine dioxide gas source can include an anolyte loop and a catholyte loop. The generator avoids or eliminates the introduction of air or other gases that can cause corrosion in the process distribution system.

Abstract: A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.

Abstract: Immunoliposomes and use thereof in highly specific and sensitive nucleic acid amplification assays relying on amplification of specific nucleic acid sequences released from encapsulation within a liposome after a receptor on the liposome couples with a targeted analyte/antigen immobilized on a select surface. The immunoliposome nucleic acid amplification assay permits both quantitative and qualitative analyte detection.

Abstract: Immunoliposomes and use thereof in highly specific and sensitive nucleic acid amplification assays relying on amplification of specific nucleic acid sequences released from encapsulation within a liposome after a receptor on the liposome couples with a targeted analyte/antigen immobilized on a select surface. The immunoliposome nucleic acid amplification assay permits both quantitative and qualitative analyte detection.

Abstract: Immunoliposomes and use thereof in highly specific and sensitive nucleic acid amplification assays relying on amplification of specific nucleic acid sequences released from encapsulation within a liposome after a receptor on the liposome couples with a targeted analyte/antigen immobilized on a select surface. The immunoliposome nucleic acid amplification assay permits both quantitative and qualitative analyte detection.

Abstract: A dispenser package for dispensing flexible sheets from a plurality of stacks of releasably adhered sheets. A carrier member supports the plurality of stacks, and a lowermost sheet of each of the plurality of stacks is adhered to the carrier member. The carrier member and stacks thereon are positioned within an enclosure having a bottom wall, a top wall, and transverse side walls. The top wall defines a transverse slot, with a first end of an uppermost sheet of each of the plurality of stacks projecting through the slot. The transverse side walls of the enclosure are spaced from transverse side edges of the carrier member to afford end-to-end movement of the carrier member and stacks of sheets thereon within the chamber as sheets are dispensed.

Abstract: A method of making a repositionable adhesive backed photo media is provided. The method includes the steps of (a) providing an imageable substrate or providing a photograph; (b) providing an attachment mechanism having a carrier film with opposing first and second surfaces; a thermally activating adhesive disposed on the first surface; a repositionable adhesive disposed on the second surface; and a liner disposed on the repositionable adhesive; (c) stacking the imageable substrate or stacking the photograph with the attachment mechanism; and (4) exposing the stack to heat causing the thermally activating adhesive to bond to the imageable substrate or the photograph.

Abstract: A stretch releasable adhesive strip includes an extensible backing layer including a first adhesive region and a flexible support layer attached to the backing layer adjacent the first adhesive region that includes a second adhesive region of a repositionable pressure sensitive adhesive. To make the adhesive strip easier to handle and write on, the support layer is stiffer than the backing layer.

Abstract: A label for applying to an optical recording media including a film or paper layer coated with an ink receptive coating on one major surface and a layer of repositionable non-pressure sensitive adhesive coated onto the other major surface.

Abstract: A dispenser package for durable index tabs includes a housing attached to a base, in which the housing consists of interconnected side walls and end walls and a cover. The housing and base define a chamber for holding a stack of durable index tabs. The cover comprises a pair of flanges, each of which has one end that is attached to one of the end walls. The flanges have a pair of opposing edges that are spaced from the side walls of the housing. The opposite end of the flanges define a relatively wide opening of the cover for dispensing index tabs made of a relatively inflexible material. The flange incorporates an elliptical relief adjacent to the opening by forming an arched step in the flange wall that extends from the end of the flange that defines the cover opening toward the end wall of the housing.

Abstract: A stretch releasable adhesive strip includes an extensible backing layer including a first adhesive region and a flexible support layer attached to the backing layer adjacent the first adhesive region that includes a second adhesive region of a repositionable pressure sensitive adhesive. To make the adhesive strip easier to handle and write on, the support layer is stiffer than the backing layer.