Patents by Inventor Timothy James Jegla

Timothy James Jegla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Slo2, novel potassium channel proteins from human brain
    Patent number: 7893209
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Slo2 and Slo4, members of the Slo family of potassium channel proteins, also known as “maxi” or BK potassium channel proteins. Also provided herein are antibodies to Slo2 and Slo 4, methods of detecting Slo2 and Slo 4, methods of screening for potassium channel activators and inhibitors using biologically active Slo2 and Slo 4, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Slo2 and Slo 4.
    Type: Grant
    Filed: March 9, 2010
    Date of Patent: February 22, 2011
    Assignee: ICAgen, Inc.
    Inventors: Timothy James Jegla, Julie Dickson Witzel
  • SLO2 and SLO4, Novel Potassium Channel Proteins from Human Brain
    Publication number: 20100267930
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Slo2 and Slo4, members of the Slo family of potassium channel proteins, also known as “maxi” or BK potassium channel proteins. Also provided herein are antibodies to Slo2 and Slo 4, methods of detecting Slo2 and Slo 4, methods of screening for potassium channel activators and inhibitors using biologically active Slo2 and Slo 4, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Slo2 and Slo 4.
    Type: Application
    Filed: March 9, 2010
    Publication date: October 21, 2010
    Applicant: ICAgen, Inc.
    Inventors: Timothy James Jegla, Julie Dickson Witzel
  • SLO2 and SLO4, novel potassium channel proteins from human brain
    Patent number: 7767450
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Slo2 and Slo4, members of the Slo family of potassium channel proteins, also known as “maxi” or BK potassium channel proteins. Also provided herein are antibodies to Slo2 and Slo 4, methods of detecting Slo2 and Slo 4, methods of screening for potassium channel activators and inhibitors using biologically active Slo2 and Slo 4, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Slo2 and Slo 4.
    Type: Grant
    Filed: July 22, 2008
    Date of Patent: August 3, 2010
    Assignee: ICAgen, Inc.
    Inventors: Timothy James Jegla, Julie Dickson Witzel
  • Kv10.1, a novel voltage-gated potassium channel from human brain
    Patent number: 7528231
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Slo potassium family members such as, antibodies to Kv10 subfamily members such as Kv10.1, methods of detecting Kv10, subfamily members such as Kv10.1, methods of screening for potassium channel activators and inhibitors using biologically active Kv10 subfamily members such as Kv10.1, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Kv10 subfamily members such as Kv10.1.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: May 5, 2009
    Assignee: Icagen, Inc.
    Inventor: Timothy James Jegla
  • SLO2 AND SLO4, NOVEL POTASSIUM CHANNEL PROTEINS FROM HUMAN BRAIN
    Publication number: 20090017534
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Slo2 and Slo4, members of the Slo family of potassium channel proteins, also known as “maxi” or BK potassium channel proteins. Also provided herein are antibodies to Slo2 and Slo 4, methods of detecting Slo2 and Slo 4, methods of screening for potassium channel activators and inhibitors using biologically active Slo2 and Slo 4, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Slo2 and Slo 4.
    Type: Application
    Filed: July 22, 2008
    Publication date: January 15, 2009
    Applicant: ICAgen, Inc.
    Inventors: Timothy James Jegla, Julie Dickson Witzel
  • Slo4 potassium channel proteins
    Patent number: 7411043
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Slo2 and Slo4, members of the Slo family of potassium channel proteins, also known as “maxi” or BK potassium channel proteins. Also provided herein are antibodies to Slo2 and Slo 4, methods of detecting Slo2 and Slo 4, methods of screening for potassium channel activators and inhibitors using biologically active Slo2 and Slo 4, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Slo2 and Slo 4.
    Type: Grant
    Filed: January 4, 2006
    Date of Patent: August 12, 2008
    Assignee: Icagen, Inc.
    Inventors: Timothy James Jegla, Julie Dickson Witzel
  • BK beta subunits of Slo family potassium channels
    Patent number: 7351553
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of BK beta 2, BK beta 3, and BK beta 4, antibodies to the BK beta subunits, methods of detecting the BK beta subunits, methods of screening for modulators of Slo potassium channels comprising BK beta subunits, and kits for screening for activators and inhibitors of the Slo family potassium channels comprising BK beta subunits.
    Type: Grant
    Filed: September 2, 2005
    Date of Patent: April 1, 2008
    Assignee: Icagen, Inc.
    Inventors: Timothy James Jegla, Alan Wickenden, Yi Liu
  • KCNQ5, a novel potassium channel
    Patent number: 7309772
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of KCNQ5, antibodies to KCNQ5, methods of detecting KCNQ5, methods of screening for potassium channel activators and inhibitors using biologically active KCNQ5, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising KCNQ5.
    Type: Grant
    Filed: February 3, 2006
    Date of Patent: December 18, 2007
    Assignee: Icagen, Inc.
    Inventor: Timothy James Jegla
  • DNA encoding Slo2 and Slo4, potassium channel
    Patent number: 7041494
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Slo2 and Slo4, members of the Slo family of potassium channel proteins, also known as “maxi” or BK potassium channel proteins. Also provided herein are antibodies to Slo2 and Slo 4, methods of detecting Slo2 and Slo 4, methods of screening for potassium channel activators and inhibitors using biologically active Slo2 and Slo 4, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Slo2 and Slo 4.
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: May 9, 2006
    Assignee: ICAGEN, Inc.
    Inventors: Timothy James Jegla, Julie Dickson Witzel
  • BK beta subunits of Slo family potassium channels
    Patent number: 6994968
    Abstract: The invention provides isolated nucleic acid and amino sequences of BK beta 2, BK beta 3, and BK beta 4, antibodies to the BK beta subunits, methods of detecting the BK beta subunits, methods of screening for modulators of Slo family potassium channels comprising BK beta subunits.
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: February 7, 2006
    Assignee: Icagen, Inc.
    Inventors: Timothy James Jegla, Alan Wickenden, Yi Liu
  • Kv10.1, a novel voltage-gated potassium channel from human brain
    Publication number: 20040157261
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Slo potassium family members such as, antibodies to Kv10 subfamily members such as Kv10.1, methods of detecting Kv10, subfamily members such as Kv10.1, methods of screening for potassium channel activators and inhibitors using biologically active Kv10 subfamily members such as Kv10.1, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Kv10 subfamily members such as Kv10.1.
    Type: Application
    Filed: March 31, 2004
    Publication date: August 12, 2004
    Applicant: Icagen, Inc.
    Inventor: Timothy James Jegla
  • Nucleic acid encoding Kv10.1, a voltage-gated potassium channel from human brain
    Patent number: 6727353
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Slo potassium family members such as, antibodies to Kv10 subfamily members such as Kv10.1, methods of detecting Kv10, subfamily members such as Kv10.1, methods of screening for potassium channel activators and inhibitors using biologically active Kv10 subfamily members such as Kv10.1, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Kv10 subfamily members such as Kv10.1.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: April 27, 2004
    Assignee: Icagen, Inc.
    Inventor: Timothy James Jegla
  • NUCLEIC ACID ENCODING KV10.1 A VOLTAGE-GATED POTASSIUM CHANNEL FROM HUMAN BRAIN
    Publication number: 20040053357
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Slo potassium family members such as, antibodies to Kv10 subfamily members such as Kv10.1, methods of detecting Kv10, subfamily members such as Kv10.1, methods of screening for potassium channel activators and inhibitors using biologically active Kv10 subfamily members such as Kv10.1, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Kv10 subfamily members such as Kv10.1.
    Type: Application
    Filed: April 11, 2001
    Publication date: March 18, 2004
    Inventor: Timothy James Jegla
  • Slo2 and Slo4, novel potassium channel proteins from human brain
    Publication number: 20030017533
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Slo2 and Slo4, members of the Slo family of potassium channel proteins, also known as “maxi” or BK potassium channel proteins. Also provided herein are antibodies to Slo2 and Slo 4, methods of detecting Slo2 and Slo 4, methods of screening for potassium channel activators and inhibitors using biologically active Slo2 and Slo 4, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Slo2 and Slo 4.
    Type: Application
    Filed: August 1, 2001
    Publication date: January 23, 2003
    Applicant: ICAgen, Inc.
    Inventors: Timothy James Jegla, Julie Dickson Witzel