Patents by Inventor Timothy James Miles

Timothy James Miles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for use in antibacterial applications
    Patent number: 10683307
    Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: June 16, 2020
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Haifeng Cui, Alan Hennessy, Qi Jin, Timothy James Miles, Stephen Frederick Moss, Neil David Pearson
  • Compounds
    Patent number: 10479792
    Abstract: A compound of Formula (I), or a salt thereof, compositions comprising the compound, processes for its preparation and its use in therapy, for example in the treatment of parasitic diseases such as Chagas disease, Human African Trypanosomiasis (HAT), Animal African trypanosomiasis (AAT) and leishmaniasis, particularly visceral leishmaniasis (VL).
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: November 19, 2019
    Assignees: GiaxoSmithKline Intellectual Property Development Limited, University of Dundee
    Inventors: Stephen Brand, Peter George Dodd, Eun Jung Ko, Maria Marco Martin, Timothy James Miles, Lars Henrik Sandberg, Michael George Thomas, Stephen Thompson
  • COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS
    Publication number: 20190270755
    Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.
    Type: Application
    Filed: May 17, 2019
    Publication date: September 5, 2019
    Inventors: Haifeng CUI, Alan Hennessy, Qi Jin, Timothy James Miles, Stephen Frederick Moss, Neil David Pearson
  • Compounds for use in antibacterial applications
    Patent number: 10364254
    Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: July 30, 2019
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Haifeng Cui, Alan Hennessy, Qi Jin, Timothy James Miles, Stephen Frederick Moss, Neil David Pearson
  • Pyrazolo[3,4-D]pyrimidin derivative and its use for the treatment of leishmaniasis
    Patent number: 10253028
    Abstract: The compound 3,3,3-trifluoro-N-((1,4-trans)-4-((3-((S)-2-methylmorpholino)-IH-pyrazolo[3,4-d]pyrimidin-6-yl)amino)cyclohexyl)propane-1-sulfonamide having the Formula (I) or a salt thereof, its opposite enantiomer, compositions comprising the compound and its use in the treatment or prevention of leishmaniasis, particularly visceral leishmaniasis.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: April 9, 2019
    Assignees: GlaxoSmithKline Intellectual Property Development Limited, University of Dundee
    Inventors: Timothy James Miles, Michael George Thomas
  • COMPOUNDS FOR US IN ANTIBACTERIAL APPLICATIONS
    Publication number: 20190031680
    Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.
    Type: Application
    Filed: August 15, 2016
    Publication date: January 31, 2019
    Inventors: Haifeng CUI, Alan HENNESSY, Qi JIN, Timothy James MILES, Stephen Frederick MOSS, Neil David PEARSON
  • Imidazo[1,2-B][1,2,4]triazine derivatives as antiparasitic agents
    Patent number: 10065965
    Abstract: A compound of Formula (I), or a salt thereof, compositions comprising the compound, processes for its preparation and its use in therapy, for example in the treatment of parasitic diseases such as Chagas disease, Human African Trypanosomiasis (HAT) and leishmaniasis, particularly visceral leishmaniasis (VL).
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: September 4, 2018
    Assignees: GlaxoSmithKline Intellectual Property Development Limited, The University of Dundee
    Inventors: Stephen Brand, Elisabet Viayna Gaza, Ian Gilbert, Eun Jung Ko, Maria Marco Martin, Timothy James Miles, Lars Henrik Sandberg, Michael George Thomas
  • COMPOUNDS
    Publication number: 20180222911
    Abstract: A compound of Formula (I), or a salt thereof, compositions comprising the compound, processes for its preparation and its use in therapy, for example in the treatment of parasitic diseases such as Chagas disease, Human African Trypanosomiasis (HAT), Animal African trypanosomiasis (AAT) and leishmaniasis, particularly visceral leishmaniasis (VL).
    Type: Application
    Filed: August 3, 2016
    Publication date: August 9, 2018
    Inventors: Stephen BRAND, Peter George DODD, Eun Jung KO, Maria MARCO MARTIN, Timothy James MILES, Lars Henrik SANDBERG, Michael George THOMAS, Stephen THOMPSON
  • IMIDAZO[1,2-B][1,2,4]TRIAZINE DERIVATIVES AS ANTIPARASITIC AGENTS
    Publication number: 20180141949
    Abstract: A compound of Formula (I), or a salt thereof, compositions comprising the compound, processes for its preparation and its use in therapy, for example in the treatment of parasitic diseases such as Chagas disease, Human African Trypanosomiasis (HAT) and leishmaniasis, particularly visceral leishmaniasis (VL).
    Type: Application
    Filed: May 26, 2016
    Publication date: May 24, 2018
    Inventors: Stephen BRAND, Elisabet Viayna GAZA, Ian GILBERT, Eun Jung KO, Maria MARCO MARTIN, Timothy James MILES, Lars Henrik SANDBERG, Michael George THOMAS
  • PYRAZOLO[3,4-D]PYRIMIDIN DERIVATIVE AND ITS USE FOR THE TREATMENT OF LEISHMANIASIS
    Publication number: 20170369496
    Abstract: The compound 3,3,3-trifluoro-N-((1,4-trans)-4-((3-((S)-2-methylmorpholino)-IH-pyrazolo[3,4-d]pyrimidin-6-yl)amino)cyclohexyl)propane-1-sulfonamide having the Formula (I) or a salt thereof, its opposite enantiomer, compositions comprising the compound and its use in the treatment or prevention of leishmaniasis, particularly visceral leishmaniasis.
    Type: Application
    Filed: January 21, 2016
    Publication date: December 28, 2017
    Inventors: Timothy James MILES, Michael George THOMAS
  • Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
    Patent number: 8071592
    Abstract: Bicyclic nitrogen containing compounds and their use as antibacterials.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: December 6, 2011
    Assignee: Glaxo Group Limited
    Inventors: Lluis Ballell, David Barros, Gerald Brooks, Julia Castro Pichel, Steven Dabbs, Robert A Daines, David Thomas Davies, Jose Maria Fiandor Roman, Israil Pendrak, Modesto J Remuiñan Blanco, Jason Anthony Rossi, Ilaria Giordano, Alan Joseph Hennessy, James B Hoffman, Graham Elgin Jones, Timothy James Miles, Neil David Pearson, Lihua(lily) Zhang
  • COMPOUNDS
    Publication number: 20100197679
    Abstract: Bicyclic nitrogen containing compounds and their use as antibacterials
    Type: Application
    Filed: April 17, 2008
    Publication date: August 5, 2010
    Inventors: Christopher Barfoot, David Thomas Davies, Timothy James Miles, Neil David Pearson
  • Heterocyclic compounds, their preparation and their use as antibacterials
    Patent number: 7732460
    Abstract: Tricyclic nitrogen containing compounds of formula (I) and their use as antibacterials.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: June 8, 2010
    Assignee: Glaxo Group Limited
    Inventors: Nathalie Cailleau, David Thomas Davies, Alan Joseph Hennessy, Graham Elgin Jones, Timothy James Miles, Neil David Pearson
  • Pyrrolo-quinoxalinone derivatives as antibacterials
    Patent number: 7709483
    Abstract: Tricyclic nitrogen containing compounds and their use as antibacterials.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: May 4, 2010
    Assignee: Glaxo Group Limited
    Inventors: Graham Elgin Jones, Timothy James Miles, Neil David Pearson
  • AZATRICYCLIC COMPOUNDS AND THEIR USE
    Publication number: 20100004230
    Abstract: Tricyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: July 3, 2007
    Publication date: January 7, 2010
    Applicant: GLAXO GROUP LIMITED
    Inventors: Gerald Brooks, Timothy James Miles, Neil David Pearson
  • DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES
    Publication number: 20090270374
    Abstract: Bicyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: July 18, 2007
    Publication date: October 29, 2009
    Inventors: Llius Ballell, David Barros, Gerald Brooks, Julia Castro Pichel, Steven Dabbs, Robert A. Daines, David Thomas Davies, Jose Maria Fiandor Roman, Israil Pendrak, Modesto J. Remuinan Blanco, Jason Anthony Rossi, Ilaria Giordano, Alan Joseph Hennessy, James B. Hoffman, Graham Elgin Jones, Timothy James Miles, Neil David Pearson, Lihua(lily) Zhang
  • Pyrrolo-Quinoxalinone Derivatives as Antibacterials
    Publication number: 20090062265
    Abstract: Tricyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: March 29, 2007
    Publication date: March 5, 2009
    Inventors: Graham Elgin Jones, Timothy James Miles, Neil David Pearson
  • Heterocyclic Compounds, their Preparation and their Use as Antibacterials
    Publication number: 20090036433
    Abstract: Tricyclic nitrogen containing compounds of formula (I) and their use as antibacterials.
    Type: Application
    Filed: December 15, 2006
    Publication date: February 5, 2009
    Inventors: Nathalie Caileau, David Thomas Davies, Alan Joseph Hennessy, Graham Elgin Jones, Timothy James Miles, Neil David Pearson
  • Compounds
    Publication number: 20080280892
    Abstract: Tricyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: October 17, 2006
    Publication date: November 13, 2008
    Inventors: Nathalie Cailleau, David Thomas Davies, Joel Michael Esken, Alan Joseph Hennessy, Senthil Kumar Kusalakumari Sukumar, Roger Edward Markwell, Timothy James Miles, Neil David Pearson
  • Compounds
    Publication number: 20080221110
    Abstract: Tricyclic nitrogen containing compounds and their use as antibacterials
    Type: Application
    Filed: October 17, 2006
    Publication date: September 11, 2008
    Inventors: Nathalie Cailleau, David Thomas Davies, Joel Michael Esken, Alan Joseph Hennessy, Senthil Kumar Kusalakumari Sukumar, Roger Edward Markwell, Timothy James Miles, Neil David Pearson