Abstract: A system comprising a client device and a server network, the client device configured to receive a query; transmit the query; receive a populated response; and display the populated response. The server network may be configured to receive the query; tokenize the query; generate an intent-match likelihood for each of a plurality of supported question intents; classify the query based on the intent-match likelihoods; evaluate each of the intent-match likelihoods to a confidence threshold; extract, via a Named Entity Recognition model, one or more entities from the query; determine one or more entity values for each of the one or more entities; query the at least one database to incorporate intent to the one or more entities and the one or more entity values; populate a response template with the one or more entity values and one or more specifics; and store the query and the populated response.

Abstract: Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.

Abstract: The present invention provides a system and method for measuring an impedance of one or more target cells before and after an electroporation protocol has been applied to the one or more target cells. The result of the impedance measurement provides a feedback control that can be implemented during and/or after the electroporation protocol to customize the electrical treatment for a particular target cell or cellular tissue.

Abstract: An STM telecommunications switch comprising a plurality of parallel data switching planes and a parallel control planes, each plane having an equal number of input ports and output ports and a central switching unit to switch each input port to any output port and wherein the data is switched in octets.

Abstract: An apparatus for sensing data from a remote optical sensor 16 has its frequency stabilised by balancing the outputs of narrow band filter 28 30, spaced about a desired frequency 36 positioned at about the 3 db down points 40 of a broad band light source 10 using voltage control, current control or temperature control to vary the frequency of the wide band light source 10. Difference between the outputs through the two narrow band filters 28 30 can be used to drive an amplifier 48 to correct the frequency of the broad band light source. The outputs through the two narrow band filters 28 30 can be converted 52 to binary numbers and fed to a microprocessor 56 which is used, via analog conversion 60, to drive the amplifier 48. The broad band light source 10 can be pulse modulated 68 to provide temporally separate light pulses 92 94 through each of the narrow band filters 28 30, measured at separate times.

Abstract: An apparatus for sensing data from a remote optical sensor 16 has its frequency stabilised by balancing the outputs of narrow band filter 28 30, spaced about a desired frequency 36 positioned at about the 3db down points 40 of a broad band light source 10 using voltage control, current control or temperature control to vary the frequency of the wide band light source 10. Difference between the outputs through the two narrow band filters 28 30 can be used to drive an amplifier 48 to correct the frequency of the broad band light source. The outputs through the two narrow band filters 28 30 can be converted 52 to binary numbers and fed to a microprocessor 56 which is used, via analog conversion 60, to drive the amplifier 48. The broad band light source 10 can be pulse modulated 68 to provide temporally separate light pulses 92 94 through each of the narrow band filters 28 30, measured at separate times.

Abstract: Statistical multiplexing gain is desirable on ATM links, especially on high-cost international links, and is provided where STM traffic is carried as cells on an ATM bearer. The cells have a bit-stream based AAL format including a map for indicating any STM idle channels. The STM idle channels are not transmitted in the cells. Preferably, the format is AAL Type 1 for structured data, and the map is carried using an extension mechanism of that format.

Abstract: An ATM telecommunications switch includes a plurality of parallel data switching planes and a parallel central plane, each plane having an equal number of input ports and output ports and a central switching unit to switch each input port to any output port. The switch further includes a first rotator to connect each input port cyclically to each timeslot of the central switching unit and a second rotator to connect each timeslot of the central switching unit cyclically to each output port.