Patents by Inventor Timothy John Ritchie

Timothy John Ritchie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMPOUNDS
    Publication number: 20120238559
    Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
    Type: Application
    Filed: December 3, 2010
    Publication date: September 20, 2012
    Applicant: GLAXO GROUP LIMITED
    Inventors: Ian Robert Baldwin, Kenneth David Down, Paul Faulder, Simon Gaines, Julie Nicole Hamblin, Joelle Le, Christopher James Lunniss, Nigel James Parr, Timothy John Ritchie, John Edward Robinson, Juliet Kay Simpson, Christian Alan Paul Smethurst
  • AZA-BICYCLOALKYL ETHERS AND THEIR USE AS ALPHA7-NACHR AGONISTS
    Publication number: 20120220599
    Abstract: The present invention relates to 1-aza-bicycloalkyl derivatives of formula I, wherein X is CH2 or a single bond; Y is a group of formula and wherein R has the meanings as defined in the specification, which compounds are alpha 7 nicotinic acetylcholine receptor (nAChR) agonists; to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: May 2, 2012
    Publication date: August 30, 2012
    Inventors: Dominik FEUERBACH, Konstanze HURTH, Timothy John RITCHIE
  • Aza-bicycloalkyl ethers and their use as alpha7-nAChR agonists
    Patent number: 8236803
    Abstract: The present invention relates to 1-aza-bicycloalkyl derivatives of formula I, wherein X is CH2 or a single bond; Y is a group of formula and wherein R has the meanings as defined in the specification, which compounds are alpha 7 nicotinic acetylcholine receptor (nAChR) agonists; to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: August 7, 2012
    Assignee: Novartis AG
    Inventors: Dominik Feuerbach, Konstanze Hurth, Timothy John Ritchie
  • QUINAZOLINONE DERIVATIVES USEFUL AS VANILLOID ANTAGONISTS
    Publication number: 20120184571
    Abstract: The present invention relates to the use of a quinazolinone compound of the formula (I) wherein R1, R2, R3, R4, R5 and m are as defined in the specification and in the claims, in free form or in salt form, and, where possible, in acid addition salt form, as a vanilloid.
    Type: Application
    Filed: March 29, 2012
    Publication date: July 19, 2012
    Inventors: Timothy John RITCHIE, Andrew James Culshaw, Christopher Thomas Brain, Edward Karol Dziadulewicz, Terance William Hart
  • Quinazolinone derivatives useful as vanilloid antagonists
    Patent number: 8211902
    Abstract: The present invention relates to the use of a quinazolinone compound of the formula (I) wherein R1, R2, R3, R4, R5 and m are as defined in the specification and in the claims, in free form or in salt form, and, where possible, in acid addition salt form, as a vanilloid.
    Type: Grant
    Filed: April 19, 2011
    Date of Patent: July 3, 2012
    Assignee: Novartis AG
    Inventors: Timothy John Ritchie, Andrew James Culshaw, Christopher Thomas Brain, Edward Karol Dziadulewicz, Terance William Hart
  • 4-carboxamide indazole derivatives useful as inhibitors of PI3-kinases
    Patent number: 8163743
    Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of P13-kinase activity.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: April 24, 2012
    Assignee: GlaxoGroupLimited
    Inventors: Ian Robert Baldwin, Kenneth David Down, Paul Faulder, Simon Gaines, Julie Nicole Hamblin, Katherine Louise Jones, Joelle Le, Christopher James Lunniss, Nigel James Parr, Timothy John Ritchie, Christian Alan Paul Smethurst, Yoshiaki Washio
  • Pyrazole Derivatives Used as CCR4 Receptor Antagonists
    Publication number: 20120015932
    Abstract: Indazole compounds, processes for their preparation, intermediates usable in these processes, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: February 24, 2010
    Publication date: January 19, 2012
    Inventors: Heather Hobbs, Simon Teanby Hodgson, Yannick Maurice LaCroix, Deborah Needham, Nigel James Parr, Panayiotis Alexandrou Procopiou, Timothy John Ritchie, Michael David Woodrow
  • QUINAZOLINONE DERIVATIVES USEFUL AS VANILLOID ANTAGONISTS
    Publication number: 20110195983
    Abstract: The present invention relates to the use of a quinazolinone compound of the formula (I) wherein R1, R2, R3, R4, R5 and m are as defined in the specification and in the claims, in free form or in salt form, and, where possible, in acid addition salt form, as a vanilloid.
    Type: Application
    Filed: April 19, 2011
    Publication date: August 11, 2011
    Inventors: Timothy John Ritchie, Andrew James Culshaw, Christopher Thomas Brain, Edward Karol Dziadulewicz, Terance William Hart
  • Novel Compounds
    Publication number: 20110183973
    Abstract: The invention is directed to certain novel compounds directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
    Type: Application
    Filed: June 3, 2009
    Publication date: July 28, 2011
    Inventors: Ian Robert Baldwin, Kenneth David Down, Paul Faulder, Simon Gaines, Julie Nicole Hamblin, Paul Spencer Jones, Joelle Le, Nigel James Parr, Timothy John Ritchie, John Edward Robinson, Juliet Kay Simpson, Christian Alan Paul Smethurst
  • BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES
    Publication number: 20110178063
    Abstract: The invention is directed to certain novel compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
    Type: Application
    Filed: June 3, 2009
    Publication date: July 21, 2011
    Applicant: GLAXO GROUP LIMITED
    Inventors: Ian Robert Baldwin, Kenneth David Down, Paul Faulder, Simon Gaines, Julie Nicole Hamblin, Joelle Le, Christopher James Lunniss, Nigel James Parr, Timothy John Ritchie, John Edward Robinson, Juliet Kay Simpson, Christian Alan Paul Smethurst
  • Novel Compounds
    Publication number: 20110118246
    Abstract: The invention is directed to to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
    Type: Application
    Filed: June 3, 2009
    Publication date: May 19, 2011
    Inventors: Ian Robert Baldwin, Kenneth David Down, Paul Faulder, Simon Gaines, Julie Nicole Hamblin, Joelle Le, Christopher James Lunniss, Nigel James Parr, Timothy John Ritchie, Juliet Kay Simpson, Christian Alan Paul Smethurst
  • 4-CARBOXAMIDE INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF P13-KINASES
    Publication number: 20110112070
    Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of P13-kinase activity.
    Type: Application
    Filed: June 3, 2009
    Publication date: May 12, 2011
    Inventors: Ian Robert Baldwin, Kenneth David Down, Paul Faulder, Simon Gaines, Julie Nicole Hamblin, Katherine Louise Jones, Joelle Le, Christopher James Lunniss, Nigel James Parr, Timothy John Ritchie, Christian Alan Paul Smethurst, Yoshiaki Washio
  • Chromone derivatives useful as antagonists of VR1 receptors
    Patent number: 7732435
    Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to their use as medicaments and to medicaments comprising them.
    Type: Grant
    Filed: December 5, 2006
    Date of Patent: June 8, 2010
    Assignee: Novartis AG
    Inventors: Andrew James Culshaw, Christopher Thomas Brain, Edward Karol Dziadulewicz, Lee Edwards, Terance William Hart, Timothy John Ritchie
  • Trisubstituted Quinazolinone Derivatives as Vanilloid Antagonists
    Publication number: 20090082365
    Abstract: The present invention relates to quinazolinone compounds of the formula wherein R2, R3, R5, R6, R7 and R8 are as defined in the specification and in the claims, in free form or in salt form, processes for their preparation and their use as pharmaceuticals, particularly in the treatment of disorders ameliorated by administration of TRPV1 antagonists.
    Type: Application
    Filed: December 6, 2006
    Publication date: March 26, 2009
    Inventors: Gurdip Bhalay, Andrew James Culshaw, Edward Karol Dziadulewicz, Christopher Thomas Brain, Timothy John Ritchie, David Beattie, Kamlesh Jagdis Bala, Alice Brewer, Glyn Hughes
  • AZA-BICYCLOALKYL ETHERS AND THEIR USE AS ALPHA7-NACHR AGONISTS
    Publication number: 20090054446
    Abstract: The present invention relates to 1-aza-bicycloalkyl derivatives of formula I, wherein X is CH2 or a single bond; Y is a group of formula and wherein R has the meanings as defined in the specification, which compounds are alpha 7 nicotinic acetylcholine receptor (nAChR) agonists; to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: October 31, 2008
    Publication date: February 26, 2009
    Inventors: Dominik FEUERBACH, Konstanze Hurth, Timothy John Ritchie
  • Quinazolinone Derivatives as Vanilloid Antagonists
    Publication number: 20080318940
    Abstract: The invention relates to quinazolinone compounds of the formula wherein the R groups are defined in the specification, processes for their preparation and their use as pharmaceuticals, particularly in the treatment of disorders ameliorated by administration of TRPV1 antagonists.
    Type: Application
    Filed: December 6, 2006
    Publication date: December 25, 2008
    Inventors: Edward Karol Dziadulewicz, Christopher Thomas Brain, Timothy John Ritchie, Andrew James Culshaw
  • Chromone Derivatives Useful as Antagonists of Vr1 Receptors
    Publication number: 20080312316
    Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to their use as medicaments and to medicaments comprising them.
    Type: Application
    Filed: December 5, 2006
    Publication date: December 18, 2008
    Inventors: Andrew James Culshaw, Christopher Thomas Brain, Edward Karol Dziadulewicz, Lee Edwards, Terance William Hart, Timothy John Ritchie
  • Quinazolinone Derivatives Useful as Vanilloid Antagonists
    Publication number: 20080194595
    Abstract: The present invention relates to the use of a quinazolinone compound of the formula (I) wherein R1, R2, R3, R4, R5 and m are as defined in the specification and in the claims, in free form or in salt form, and, where possible, in acid addition salt form, as a vanilloid.
    Type: Application
    Filed: June 8, 2005
    Publication date: August 14, 2008
    Inventors: Timothy John Ritchie, Andrew James Culshaw, Christopher Thomas Brain, Edward Karol Dziadulewicz, Terance William Hart
  • Chromone Derivatives Useful as Vanilloid Antagonists
    Publication number: 20080114056
    Abstract: The present invention relates to the use of a chromone compound of the formula wherein R1, R2, R3, R4, R5 and m are as defined in the specification and in the claims, in free form or in salt form, and, where possible, in acid addition salt form, as a vanilloid antagonist.
    Type: Application
    Filed: June 8, 2005
    Publication date: May 15, 2008
    Inventors: Timothy John Ritchie, Andrew James Culshaw, Terance William Hart, Christopher Thomas Brain, Edward Karol Dziadulewicz
  • Bradykinin receptor antagonists
    Patent number: 6958331
    Abstract: The invention relates to sulfonyl amine derivatives of formula IA wherein R5A, X1, X2, R9 and R10 are as defined herein, which derivatives are useful as bradykinin B1 receptor antagonists.
    Type: Grant
    Filed: June 2, 2000
    Date of Patent: October 25, 2005
    Assignee: Novartis AG
    Inventors: Christopher Thomas Brain, William Cantrell, Andrew James Culshaw, Edward Karol Dziadulewicz, Terance William Hart, Timothy John Ritchie, Liladhar Waykole