Abstract: An aerosol dispenser comprising a pressurised aerosol can and a closure comprising an aerosol valve held within a retention chassis, the retention chassis being associated with a flexible sealing collar designed to radially surround the retention chassis and to seal against the edge of an opening in the aerosol can, wherein the retention chassis is axially moveable relative to the sealing collar and wherein the sealing collar is of outer diameter greater than the inner diameter of the opening in the aerosol can and is sufficiently flexible to flex through the opening in the aerosol can when the retention chassis is in a first axial position relative to the sealing collar and wherein the sealing collar is firmly held against the edge of the opening in the aerosol can when the retention chassis is in a second axial position relative to the sealing collar.

Abstract: Data address management systems, methods, devices and uses for minimizing interaction with data consumers' data on data storage devices, an embodiment comprising an external bus for communicatively interfacing the data storage system and data consumers; at least one storage medium components, each storage medium component comprising a plurality of storage locations having a unique storage location indicators; a translation layer module comprising a data address space having data addresses associable with storage location indicators; and a controller configured to store data in the storage locations and creating associations in the translation layer module between data addresses and the physical location indicators; wherein the data address space is accessible by the data consumer for addressing requests relating to data stored on the storage device and wherein the controller is configured to manipulate the arrangement of the data addresses in the data address space.

Abstract: The invention is in the field of TNF signalling. Compounds have been identified which are capable of modulating signalling of TNF trimers through receptors. Methods of identifying such compounds are therefore provided. The compounds themselves have utility in therapy.

Abstract: An actuation interface for actuating a cover (e.g., a vehicle window, door, sun roof, partition, gate, etc.) that selectively covers an opening in a compartment may be configured for actuation based at least in part on a number of concurrent touch inputs. The cover may be controlled by receiving a touch input at the actuation interface, and detecting a number of concurrent touch inputs that are received as part of the touch input. The cover may be actuated to move based at least in part on a determination of the number of concurrent touch inputs that are received at the actuation interface.

Abstract: Disclosed herein are methods for making a thin film device and/or for reducing warp in a thin film device, the methods comprising applying at least one metal film to a convex surface of a glass substrate, wherein the glass substrate is substantially dome-shaped. Other methods disclosed include methods of determining the concavity of a glass sheet. The method includes determining the orientation of the concavity and measuring a magnitude of the edge lift of the sheet when the sheet is supported by a flat surface and acted upon by gravity. Thin film devices made according to these methods and display devices comprising such thin film devices are also disclosed herein.

Abstract: Systems and methods are provided for use with a thermoplastic road marking system (e.g., paint truck). The systems and methods control an insertion or replenishment rate of unmelted thermoplastic paint feed stock into a thermoplastic melter based, at least in part, on the rate that thermoplastic melt is being applied to a marking surface. By substantially matching the replenishment rate into the thermoplastic melter with the application rate, thermal variance within the thermoplastic melter is reduced, which improves the consistency of marking lines applied to surfaces.

Abstract: A supply item has toner for use in an imaging device. A chip has memory storing quanta indicating allowed usage of the supply item over its lifetime and a multiplier correlating the quanta to toner mass. The imaging device requires quanta to conduct imaging operations and loads the quanta and multiplier by way of a certificate stored in the memory. The imaging device retrieves quanta from the chip over time and both devices keep tally. Initialization between the supply item and imaging device includes providing encrypted and unencrypted instances of firmware versions and certificates from the supply item that the imaging device can compare for security. Alternatively, the supply item defines a fuser assembly, imaging unit, intermediate transfer member, or other component installed for use in the imaging device.

Abstract: It has been demonstrated that certain compounds bind to TNF and stabilise a conformation of trimeric TNF that binds to the TNF receptor. Accordingly, these compounds can be used as modulators of TNF. A new assay for identifying compounds with this mechanism of action is also disclosed.

Abstract: An automated tape applicator that applies pavement marking tape to a pavement surface. The automated tape applicator may include dual knives for cutting two or more patterns simultaneously, a hinged frame that permits an adhesion roller to be lifted off the ground when not in active use, an electronic clutch for selectively engaging a tape feed mechanism, a swiveling front tire, an automated controller for simultaneous application of multiple markings and accurate dimensioning, and/or replaceable knife inserts.

Abstract: Provided herein is technology relating to testing fluid specimens and particularly, but not exclusively, to apparatuses, devices, methods, systems, and kits for testing a fluid specimen, e.g. urine, saliva, or other body fluids, to detect specified chemical components in the specimen.

Abstract: A hypersonic propulsion engine includes: a turbine engine including a compressor section, a combustion section, and a turbine section arranged in serial flow order, the turbine engine defining a turbine engine inlet upstream of the compressor section and a turbine engine exhaust downstream of the turbine section; a ducting assembly defining a bypass duct having a substantially annular shape and extending around the turbine engine, an afterburning chamber located downstream of the bypass duct and at least partially aft of the turbine engine exhaust, and an inlet section located at least partially forward of the bypass duct and the turbine engine inlet; and an inlet precooler positioned at least partially within the inlet section of the ducting assembly and upstream of the turbine engine inlet, the bypass duct, or both for cooling an airflow provided through the inlet section of the ducting assembly to the turbine engine inlet, the bypass duct, or both.

Abstract: Embodiments herein are directed to moisturizing compositions comprising interpenetrating polymer networks, methods of making moisturizing compositions and methods of using moisturizing compositions.

Abstract: A method and system for determining and implementing weight distribution of payload on an aircraft for optimizing centre of gravity of the aircraft by providing an individual weight factor for each passenger and/or crew member and their respective hand luggage and allocating at least a portion of the passengers and/or crew members seats according to the effect of passenger and/or crew member's positions on the aircraft on centre of gravity position provides advantages in determining accurately cabin payload data and cabin payload distribution for optimum fuel efficiency of an aircraft on a flight. Thus, fuel may be saved and carbon dioxide emissions may be reduced.

Abstract: Compounds of formula (I), wherein Ar is an aryl group optionally further substituted with one or more groups R3; A is a lipophilic, hydrophobic moiety; R1 is a phosphodiester, phosphotriester, thioether or amide group; X is an unsubstituted or substituted C6 to C24 alkylene or alkenylene group, which is optionally interrupted by one or more —NR9—, —O— or —S— linkages, R2 is —YC(R4)(R5)CO2R6; and pharmaceutically acceptable salts or solvates thereof are useful as endosomolytic agents particularly for the delivery of nucleic acids useful in gene therapy.

Abstract: A common path interferometer is disclosed. The interferometer is arranged to divide an input beam into first and second beam portions directed in opposite directions around a cyclic path to form an interference pattern at a detector. The cyclic path is defined by at least two mirror regions curved in the plane of the cyclic path, such that the interference pattern represents path difference variations between the first and second beam portions. The interferometer further includes an input optic arranged in the beam path before division of the input beam into the beam portions. The input optic is configured to provide convergence to reduce the extent transversely to the plane of the cyclic path of the interference pattern at the detector. The beam and beam portions have different convergence requirements in the plane of, and transverse to the plane of, the cyclic path, which are addressed separately by the mirror regions and the input optic.

Abstract: Described are concepts, systems and techniques related to processing an input video signal intended for a first display to produce an output signal appropriate for a second display. The concepts, systems and techniques include converting using one or more transfer functions arranged to provide relative scene light values and remove or apply rendering intent of the input or output video signal, wherein the removing or applying rendering intent alters luminance.

Abstract: Systems and methods are involved with but are not limited to a semiflexible plastic piece including a device display receiving portion, a device keyboard receiving portion, and a spine portion extending therebetween, the device display receiving portion sized and shaped to receivably couple along one or more edges of a display portion of a portable electronic device, the device keyboard receiving portion sized and shaped to receivably couple along one or more edges of a keyboard portion of the portable electronic device, the semiflexible plastic piece having flexibility sufficient for the spine portion to accommodate hinged disposition between the display portion and the keyboard portion of the portable electronic device as received by the portable electronic device case. In addition, other aspects are described in the claims, drawings, and text forming a part of the present disclosure.

Abstract: A food recycler includes a base, at least one air intake opening, a gearbox, and a motor. An airflow component is on top of the motor. A fan is configured on the airflow component and a filter is positioned at an output port of the airflow component. A bucket receptacle is configured on the gearbox. The fan and the filter are configured adjacent to an upper portion of the bucket receptacle. A casing has a lower rim complimentary to a base rim. The casing has an interior volume complimentary to a fan module and an interior volume complimentary to an air filter module. A control switch and lid latch are configured in the casing and next to each other. A lid is hinged to the casing such that air flows from a bucket through the lid to the fan and back from the filter to the lid and out an exhaust vent in the lid.

Abstract: Compound of formula I: wherein: A is selected from: (i) where RF1 is H or F; (ii) (iii) a N-containing C6 heteroaryl group; and B is where X1 is either CRF2 or N, where RF2 is H or F; X2 is either CR3 or N, where R3 is selected from H, Me, Cl, F OMe; X3 is either CH or N; X4 is either CRF3 or N, where RF3 is H or F; where only one or two of X1, X2, X3 and X4 may be N; and R4 is selected from I, optionally substituted phenyl, optionally substituted C5-6 heteroaryl; optionally substituted C1-6 alkyl and optionally substituted C1-6 alkoxy, which are useful in the treatment of a condition ameliorated by the inhibition of MOZ.